Detail Information

Basic Information:


  VIRBase ID:  

HHID00026558

  Virus:  

Hepatitis B virus (HBV genotype D)

  Host:  

Homo sapiens

  Confidence Score:  

0.9612

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-129-5p:           ZBTB20:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-129-5p ZBTB20
miRBase
Accession/Entrez ID		 MIMAT0000242 26137
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DPZF//HOF//ODA-8S//PRIMS//ZNF288

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-129-5p
rs1242359724 chr7:128207890    G/A
rs1263648656 chr7:128207889    G/A
rs1274463608 chr7:128207884    G/A
rs1279636719 chr7:128207895    G/C
rs1279636719 chr7:128207895    G/T
rs756117952 chr7:128207886    T/C
rs779889090 chr7:128207891    G/T
rs1229617898 chr11:43581416    G/A
rs1289973713 chr11:43581418    T/C
rs1320545184 chr11:43581421    G/A
rs765549410 chr11:43581422    G/T
rs1331459988 chr7:128207878    T/G
rs750308373 chr7:128207883    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR ZBTB20
chr3:114083198(-) A-I      intronic
chr3:114348935(-) A-I      intronic
chr3:114270978(-) A-I      intronic
chr3:114270945(-) A-I      intronic
chr3:114734769(-) A-I      intronic
chr3:114256771(-) A-I      intronic
chr3:114256859(-) A-I      intronic
chr3:114732675(-) A-I      intronic
chr3:114270950(-) A-I      intronic
chr3:114065641(-) A-I      intronic
chr3:114065661(-) A-I      intronic
chr3:114065701(-) A-I      intronic
chr3:114083136(-) A-I      intronic
chr3:114083150(-) A-I      intronic
chr3:114083179(-) A-I      intronic
chr3:114065590(-) A-I      intronic
chr3:114656436(-) A-I      intronic
chr3:114656389(-) A-I      intronic
chr3:114270934(-) A-I      intronic
chr3:114511894(-) A-I      intronic
chr3:114511892(-) A-I      intronic
chr3:114511887(-) A-I      intronic
chr3:114348985(-) A-I      intronic
chr3:114348980(-) A-I      intronic
chr3:114348937(-) A-I      intronic
chr3:114270979(-) A-I      intronic
chr3:114348925(-) A-I      intronic
chr3:114065593(-) A-I      intronic
chr3:114065563(-) A-I      intronic
chr3:114065616(-) A-I      intronic
chr3:114270966(-) A-I      intronic
chr3:114270977(-) A-I      intronic
chr3:114065630(-) A-I      intronic
chr3:114065609(-) A-I      intronic
chr3:114312317(-) A-I      intronic
chr3:114312299(-) A-I      intronic
chr3:114783568(-) A-I      intronic
chr3:114783563(-) A-I      intronic
chr3:114783427(-) A-I      intronic
chr3:114656951(-) A-I      intronic
chr3:114656837(-) A-I      intronic
chr3:114656437(-) A-I      intronic
chr3:114656401(-) A-I      intronic
chr3:114656371(-) A-I      intronic
chr3:114656298(-) A-I      intronic
chr3:114638521(-) A-I      intronic
chr3:114638495(-) A-I      intronic
chr3:114268909(-) A-I      intronic
chr3:114511934(-) A-I      intronic
chr3:114306017(-) A-I      intronic
chr3:114305982(-) A-I      intronic
chr3:114305968(-) A-I      intronic
chr3:114295327(-) A-I      intronic
chr3:114295296(-) A-I      intronic
chr3:114295157(-) A-I      intronic
chr3:114269735(-) A-I      intronic
chr3:114269726(-) A-I      intronic
chr3:114269695(-) A-I      intronic
chr3:114269694(-) A-I      intronic
chr3:114269683(-) A-I      intronic
chr3:114269633(-) A-I      intronic
chr3:114267569(-) A-I      intronic
chr3:114267503(-) A-I      intronic
chr3:114267457(-) A-I      intronic
chr3:114263631(-) A-I      intronic
chr3:114263625(-) A-I      intronic
chr3:114263624(-) A-I      intronic
chr3:114263603(-) A-I      intronic
chr3:114445501(-) A-I      intronic
chr3:114445515(-) A-I      intronic
chr3:114466402(-) A-I      intronic
chr3:114496202(-) A-I      intronic
chr3:114499528(-) A-I      intronic
chr3:114499559(-) A-I      intronic
chr3:114511871(-) A-I      intronic
chr3:114511879(-) A-I      intronic
chr3:114496269(-) A-I      intronic
chr3:114325862(-) A-I      intronic
chr3:114325776(-) A-I      intronic
chr3:114325751(-) A-I      intronic
chr3:114325726(-) A-I      intronic
chr3:114312510(-) A-I      intronic
chr3:114312487(-) A-I      intronic
chr3:114312482(-) A-I      intronic
chr3:114312404(-) A-I      intronic
chr3:114824858(-) A-I      intronic
chr3:114824825(-) A-I      intronic
chr3:114824821(-) A-I      intronic
chr3:114824793(-) A-I      intronic
chr3:114824776(-) A-I      intronic
chr3:114824741(-) A-I      intronic
chr3:114824725(-) A-I      intronic
chr3:114263547(-) A-I      intronic
chr3:114263436(-) A-I      intronic
chr3:114263418(-) A-I      intronic
chr3:114263398(-) A-I      intronic
chr3:114220723(-) A-I      intronic
chr3:114220391(-) A-I      intronic
chr3:114220365(-) A-I      intronic
chr3:114197059(-) A-I      intronic
chr3:114196978(-) A-I      intronic
chr3:114196974(-) A-I      intronic
chr3:114091998(-) A-I      intronic
chr3:114091990(-) A-I      intronic
chr3:114091596(-) A-I      intronic
chr3:114091431(-) A-I      intronic
chr3:114083241(-) A-I      intronic
chr3:114083215(-) A-I      intronic
chr3:114083214(-) A-I      intronic
chr3:114083211(-) A-I      intronic
chr3:114083119(-) A-I      intronic
chr3:114083116(-) A-I      intronic
chr3:114083107(-) A-I      intronic
chr3:114068000(-) A-I      intronic
chr3:114065789(-) A-I      intronic
chr3:114065665(-) A-I      intronic
chr3:114065618(-) A-I      intronic
chr3:114821786(-) A-I      intronic
chr3:114821781(-) A-I      intronic
chr3:114312378(-) A-I      intronic
chr3:114065625(-) A-I      intronic
chr3:114271052(-) A-I      intronic
chr3:114268896(-) A-I      intronic
chr3:114263443(-) A-I      intronic
chr3:114499450(-) A-I      intronic
chr3:114263584(-) A-I      intronic
chr3:114068006(-) A-I      intronic
chr3:114295345(-) A-I      intronic
chr3:114065736(-) A-I      intronic
chr3:114847328(-) A-I      intronic
chr3:114065713(-) A-I      intronic
chr3:114511909(-) A-I      intronic
chr3:114108555(-) A-I      intronic
chr3:114851529(-) A-I      intronic
chr3:114065673(-) A-I      intronic
chr3:114267477(-) A-I      intronic
chr3:114846245(-) A-I      intronic
chr3:114091821(-) A-I      intronic
chr3:114826089(-) A-I      intronic
chr3:114065671(-) A-I      intronic
chr3:114301502(-) A-I      intronic
chr3:114263553(-) A-I      intronic
chr3:114468144(-) A-I      intronic
chr3:114783366(-) A-I      intronic
chr3:114270889(-) A-I      intronic
chr3:114333721(-) A-I      intronic
chr3:114325708(-) A-I      intronic
chr3:114263555(-) A-I      intronic
chr3:114270886(-) A-I      intronic
chr3:114511958(-) A-I      intronic
chr3:114066030(-) A-I      intronic
chr3:114400190(-) A-I      intronic
chr3:114442854(-) A-I      intronic
chr3:114448748(-) A-I      intronic
chr3:114826215(-) A-I      intronic
chr3:114348745(-) A-I      intronic
chr3:114783436(-) A-I      intronic
chr3:114067867(-) A-I      intronic
chr3:114755488(-) A-I      intronic
chr3:114065806(-) A-I      intronic
chr3:114270877(-) A-I      intronic
chr3:114067854(-) A-I      intronic
chr3:114448858(-) A-I      intronic
chr3:114638443(-) A-I      intronic
chr3:114445647(-) A-I      intronic
chr3:114824762(-) A-I      intronic
chr3:114065635(-) A-I      intronic
chr3:114798373(-) A-I      intronic
chr3:114825352(-) A-I      intronic
chr3:114065640(-) A-I      intronic
chr3:114269709(-) A-I      intronic
chr3:114263515(-) A-I      intronic
chr3:114824803(-) A-I      intronic
chr3:114496189(-) A-I      intronic
chr3:114267625(-) A-I      intronic
chr3:114656834(-) A-I      intronic
chr3:114092033(-) A-I      intronic
chr3:114825219(-) A-I      intronic
chr3:114062645(-) A-I      intronic
chr3:114496268(-) A-I      intronic
chr3:114301500(-) A-I      intronic
chr3:114496164(-) A-I      intronic
chr3:114325755(-) A-I      intronic
chr3:114325777(-) A-I      intronic
chr3:114065729(-) A-I      intronic
chr3:114067961(-) A-I      intronic
chr3:114783367(-) A-I      intronic
chr3:114065611(-) A-I      intronic
chr3:114511999(-) A-I      intronic
chr3:114825177(-) A-I      intronic
chr3:114267462(-) A-I      intronic
chr3:114512022(-) A-I      intronic
chr3:114656963(-) A-I      intronic
chr3:114496239(-) A-I      intronic
chr3:114325883(-) A-I      intronic
chr3:114824802(-) A-I      intronic
chr3:114325845(-) A-I      intronic
chr3:114499508(-) A-I      intronic
chr3:114656463(-) A-I      intronic
chr3:114065765(-) A-I      intronic
chr3:114656433(-) A-I      intronic
chr3:114837196(-) A-I      intronic
chr3:114067802(-) A-I      intronic
chr3:114400105(-) A-I      intronic
chr3:114326287(-) A-I      intronic
chr3:114499463(-) A-I      intronic
chr3:114326332(-) A-I      intronic
chr3:114091604(-) A-I      intronic
chr3:114065728(-) A-I      intronic
chr3:114325683(-) A-I      intronic
chr3:114267463(-) A-I      intronic
chr3:114472316(-) A-I      intronic
chr3:114065647(-) A-I      intronic
chr3:114826151(-) A-I      intronic
chr3:114312330(-) A-I      intronic
chr3:114826253(-) A-I      intronic
chr3:114826127(-) A-I      intronic
chr3:114825148(-) A-I      intronic
chr3:114656407(-) A-I      intronic
chr3:114312396(-) A-I      intronic
chr3:114496186(-) A-I      intronic
chr3:114067790(-) A-I      intronic
chr3:114571375(-) A-I      intronic
chr3:114755285(-) A-I      intronic
chr3:114499562(-) A-I      intronic
chr3:114325725(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED ZBTB20
chr3:114258979(-) A-G intron -    22484847
chr3:114065611(-) A-G intron -    22484847
chr3:114065625(-) A-G intron -    22484847
chr3:114065671(-) A-G intron -    22484847
chr3:114065673(-) A-G intron -    22484847
chr3:114065713(-) A-G intron -    22484847
chr3:114067854(-) A-G intron -    22484847
chr3:114067985(-) A-G intron -    22484847
chr3:114068006(-) A-G intron -    22484847
chr3:114269780(-) G-A intron -    22484847
chr3:114271052(-) A-G intron -    22484847
chr3:114325708(-) A-G intron -    22484847
chr3:114325725(-) A-G intron -    22484847
chr3:114325845(-) A-G intron -    22484847
chr3:114325882(-) A-G intron -    22484847
chr3:114325883(-) A-G intron -    22484847
chr3:114406995(-) A-G intron -    22484847
chr3:114480598(-) G-A intron -    22484847
chr3:114496164(-) A-G intron -    22484847
chr3:114496169(-) A-G intron -    22484847
chr3:114496186(-) A-G intron -    22484847
chr3:114496189(-) A-G intron -    22484847
chr3:114496239(-) A-G intron -    22484847
chr3:114496268(-) A-G intron -    22484847
chr3:114499463(-) A-G intron -    22484847
chr3:114499508(-) A-G intron -    22484847
chr3:114499562(-) A-G intron -    22484847
chr3:114656433(-) A-G intron -    22484847
chr3:114656463(-) A-G intron -    22484847
chr3:114656755(-) A-G intron -    22484847
chr3:114656963(-) A-G intron -    22484847
chr3:114824762(-) A-G intron -    22484847
chr3:114824802(-) A-G intron -    22484847
chr3:114824803(-) A-G intron -    22484847
chr3:114824935(-) A-G intron -    22484847
chr3:114825213(-) A-G intron -    22484847
chr3:114825219(-) A-G intron -    22484847
chr3:114826089(-) A-G intron -    22484847
chr3:114826151(-) A-G intron -    22484847
chr3:114826215(-) A-G intron -    22484847
chr3:114826253(-) A-G intron -    22484847
chr3:114851529(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZBTB20
chr3:114057021-114057022(-) m6A 3'UTR       24981863//27773535
chr3:114057051-114057052(-) m6A 3'UTR       24981863//27773535//22608085
chr3:114057128-114057129(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr3:114057134-114057135(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr3:114057333-114057334(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr3:114057360-114057361(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr3:114057381-114057382(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr3:114057407-114057408(-) m6A 3'UTR       24284625//24981863//27773535//22575960//22608085
chr3:114057695-114057696(-) m6A 3'UTR       24981863//27773535
chr3:114057793-114057794(-) m6A 3'UTR       24981863//27773535
chr3:114057801-114057802(-) m6A 3'UTR       24981863//27773535
chr3:114057814-114057815(-) m6A 3'UTR       24981863//27773535
chr3:114057819-114057820(-) m6A 3'UTR       24981863//27773535
chr3:114057824-114057825(-) m6A 3'UTR       24981863//27773535
chr3:114057940-114057941(-) m6A CDS       24284625//24981863//27773535//22575960
chr3:114058009-114058010(-) m6A CDS       24284625//24981863//22575960
chr3:114058054-114058055(-) m6A CDS       24284625//24981863
chr3:114069149-114069150(-) m6A CDS//intron       24284625//24981863
chr3:114069154-114069155(-) m6A CDS//intron       24284625//24981863
chr3:114069168-114069169(-) m6A CDS//intron       24284625//24981863
chr3:114069315-114069316(-) m6A CDS//intron       24284625//24981863//27773535
chr3:114069480-114069481(-) m6A CDS//intron       24284625//27773535//22575960
chr3:114069486-114069487(-) m6A CDS//intron       24284625//27773535//22575960
chr3:114069599-114069600(-) m6A CDS//intron       24284625//27773535//22575960
chr3:114069642-114069643(-) m6A CDS//intron       27773535//27371828
chr3:114069657-114069658(-) m6A CDS//intron       27773535//27371828
chr3:114069709-114069710(-) m6A CDS//intron       24981863//27371828
chr3:114069722-114069723(-) m6A CDS//intron       24981863//27371828
chr3:114069842-114069843(-) m6A CDS//intron       24284625//24981863//27773535//27371828
chr3:114069848-114069849(-) m6A CDS//intron       24284625//24981863//27773535//27371828
chr3:114069960-114069961(-) m6A CDS//intron       24284625//24981863//27773535//27371828
chr3:114070002-114070003(-) m6A CDS//intron       24284625//24981863//27773535//27371828
chr3:114070073-114070074(-) m6A CDS//intron       24284625
chr3:114070110-114070111(-) m6A CDS//intron       24284625
chr3:114070202-114070203(-) m6A CDS//intron       24284625//24981863//27371828//27773536//22575960
chr3:114070295-114070296(-) m6A CDS//intron       24284625//24981863//27371828//27773536//22575960//22608085
chr3:114070307-114070308(-) m6A CDS//intron       24284625//24981863//27371828//27773536//22575960//22608085
chr3:114070374-114070375(-) m6A CDS//intron       24981863//27371828//27773536//22575960
chr3:114070647-114070648(-) m6A CDS//intron       27773535//22575960
chr3:114099092-114099093(-) m6A 5'UTR//CDS//exon       27773535
chr3:114099128-114099129(-) m6A 5'UTR//CDS//exon       27773535
chr3:114099152-114099153(-) m6A 5'UTR//CDS//exon       27773535
chr3:114099227-114099228(-) m6A 5'UTR//CDS//exon       27773535
chr3:114099237-114099238(-) m6A 5'UTR//CDS//exon       27773535
chr3:114107919-114107920(-) m6A 5'UTR//exon       27773535
chr3:114137927-114137928(-) m6A exon//intron       27773535
chr3:114137984-114137985(-) m6A exon//intron       27773535
chr3:114377413-114377414(-) m6A exon//intron       27773535
chr3:114377492-114377493(-) m6A exon//intron       27773535
chr3:114377587-114377588(-) m6A exon//intron       27773535
chr3:114377597-114377598(-) m6A exon//intron       27773535
chr3:114819061-114819062(-) m6A exon//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-129-5p
Exosome Jurkat-derived T cell line (J77cl20)     21505438
Exosome Renal cancer cells     21670082
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Blood     -
Microvesicle Cerebrospinal fluid     24797360
Microvesicle Blood|Fibroblasts|Mesenchymal stem cells|Urine     -
ZBTB20
Chromatin K562 cells     -
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm HCC cell line (HepG2)     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-TO cells     22532836
Nucleus HCC cell line (HepG2)|HeLa-S3 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-129-5p
Iodine Green 9956454 Drug sensitive
Kahalalide F 9898671 Drug resistant
Midostaurin 9829523 Drug resistant
2,5-Dimethyl-1,4-benzoquinone 8718 Drug sensitive
Acid Green 27 80837 Drug sensitive
L-2-Aminobutyric acid 80283 Drug sensitive
Coptisine chloride 72321 Drug sensitive
Ixabepilone 6445540 Drug sensitive
Verrucarin A 6326658 Drug sensitive
Tributyrin 6050 Drug sensitive
3-Deazauridine 54684286 Drug sensitive
Herveline O 5459269 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
Simvastatin 54454 Drug resistant
2-Methoxy-5-[(E)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenol 5386397 Drug sensitive
Centaureidin 5315773 Drug sensitive
Spiperone 5265 Drug resistant
Kekule 499328 Drug sensitive
Lychnopholide 49767028 Drug sensitive
(S)-(+)-Tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 46907787 Drug sensitive
1-(4-(Benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H-pyrazol-3-yl)phenyl)urea 44587530 Drug sensitive
2,6-Epoxy-2H-1-benzoxocin-5(6H)-one, 6,8-dimethyl- 434882 Drug sensitive
Di-n-octyl-secalonsaure A 430141 Drug sensitive
beta-Lapachone 3885 Drug sensitive
Lapachol 3884 Drug sensitive
2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Naphtho[2,3-f]quinoxaline-7,12-dione, 3-hydroxy-2-methyl- 371563 Drug resistant
Amchloramide 364434 Drug sensitive
2,7-Dicyanoxanthone 363841 Drug sensitive
1-Chloro-3-(3-chloropropylsulfonylsulfanyl)propane 355643 Drug sensitive
5-Fluorocytosine arabinoside 352938 Drug sensitive
Dichloroallyl lawsone 277767 Drug sensitive
2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-N-[2-(methylamino)ethyl]-1H-imidazo[4,5-c]pyridine-7-carboxamide 25023715 Drug resistant
2-(4-((Oxiran-2-yl)methoxy)styryl)-4,5-dihydrooxazole 24206038 Drug sensitive
Prumycin HCl 24197905 Drug resistant
Methyl 1,6,8,14a-tetrahydroxy-11-[(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)amino]-6a-methoxy-3-methyl-7,9,12,14-tetraoxo-5,6-dihydrobenzo[a]tetracene-2-carboxylate 197261 Drug sensitive
Diphenyltin dichloride 14342 Drug sensitive
C8, Carbonyl prodigiosine 135540857 Drug sensitive
(2Z)-3-Ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)-2-methylprop-2-enylidene]-1,3-benzothiazole;hydroiodide 129893658 Drug sensitive
15-Deacetylsergeolide 125729 Drug sensitive
(2S,4S,5R)-20-De(1-hydroxypropyl)-6-demethyl-2,6-diethyl-5-hydroxy-20-(1-hydroxybutyl)lysocellin 124081057 Drug sensitive
Unii-C616DV5Y11 117587576 Drug sensitive
N-(2-Aminophenyl)-4-{1-[(benzylamino)methyl]vinyl}benzamide 11588476 Drug sensitive
Acetylenedicarboxamide 10971 Drug sensitive
(1R,5S,7R,13R,20R)-11-Hydroxy-5,10,13,14,15-pentamethoxy-7,20-diphenyl-2,8,21-trioxapentacyclo[11.8.0.01,17.03,12.04,9]henicosa-3,9,11,14,17-pentaen-16-one 101664521 Drug sensitive
Chimaphilin 101211 Drug sensitive
[(1S,2S,4Z,8Z,12R,13S)-12-Hydroxy-4,8,12-trimethyl-16-methylidene-15-oxo-14-oxabicyclo[11.3.1]heptadeca-4,8-dien-2-yl] acetate 100921072 Drug sensitive
1-[(2-cyclohexymethoxy)methyl]-5-ethyl-6-iodouracil - Drug resistant
toxin .delta.53l - Drug resistant
tp4ek - Drug resistant
1,6,7,8-tetra-o-phenylcarbamoylcastnospermine - Drug sensitive
1,8-naphthyridin-4(1h)-one, 2-(3-chlorophenyl)-5-methyl- - Drug sensitive
3,4-diphenylisoxazolo[3,4-d]pyridazin-7(6h)-one - Drug sensitive
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug sensitive
4-[3-(3,4-dihydro-1H-isoquinolin-2-yl)prop-1-en-2-yl]-N-pyrazin-2-ylbenzamide - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
4-thiomorpholinecarbodithioic acid, antimony complex - Drug sensitive
7h-5,6-dithioleno[4,3-d]uracil - Drug sensitive
benzo[1,2-b:4,5-b']dithiophene-4,8-diol, dipropionate - Drug sensitive
benzo[1,2-c:4,5-c']dipyrrole-1,3,5,7(2h,6h)-tetraimine - Drug sensitive
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
phosphonium, (3-bromopropyl)triphenyl- bromide - Drug sensitive
propanedinitrile, [(3,5-dibromo-2-ethoxyphenyl)methylene]- - Drug sensitive
purine, 2,6,8-tris(hexylamino)- - Drug sensitive
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug sensitive
1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug sensitive
antibiotic a54556 - Drug sensitive
chlorambucil-spermidine - Drug sensitive
chlorobis(4-ethyltropolonato)bismuth(iii) - Drug sensitive
dolavaline - Drug sensitive
geldanamycin analog - Drug sensitive
hyperforinacetate - Drug sensitive
pancratium littorale - Drug sensitive
streptorubrin - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-129-5p
Vincristine 5978 Drug interaction    RC00001560
Prednisone 5865 Drug interaction    RC00001559
D-Glucose 5793 Drug interaction    RC00001558
Decitabine 451668 Drug interaction    RC00001567
Trichostatin A 444732 Drug interaction    RC00001566
Bortezomib 387447 Drug interaction    RC00001565
Etoposide 36462 Drug interaction    RC00001563
Paclitaxel 36314 Drug interaction    RC00001562
5-Fluorouracil 3385 Drug interaction    RC00001557
Doxorubicin 31703 Drug interaction    RC00001561
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00001556
Docetaxel 148124 Drug interaction    RC00001564
Chemotherapy - Drug interaction    RC00008829
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-129-5p
Gemcitabine 60750       30117016
Cisplatin 5702198       28619508
Paclitaxel 36314       23627607
Paclitaxel 36314       27831649
Doxorubicin 31703       25344911
Doxorubicin 31703       27831649
Doxorubicin 31703       29802821
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       20162574
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       25344911
Methyl (9R,10S,11S,12R,19R)-11-acetyloxy-12-ethyl-4-[(13S,15R,17S)-17-ethyl-17-hydroxy-13-methoxycarbonyl-1,11-diazatetracyclo[13.3.1.04,12.05,10]nonadeca-4(12),5,7,9-tetraen-13-yl]-8-formyl-10-hydroxy-5-methoxy-8,16-diazapentacyclo[10.6.1.01,9.02,7.016,19]nonadeca-2,4,6,13-tetraene-10-carboxylate 134755071       27831649
Trastuzumab -       29258115
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-129-5p
Irinotecan       60838

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-129-5p
Interactor2: ZBTB20

Evidence Support:


Strong-Evidence Dual luciferase reporter assay//qRT-PCR//Western blot
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 32703411 Target region None
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line HepAD38 cells//HepG2 cells Interactor2 expression None
Description Here, we found that the common sequences of all HBV RNAs and that encoding the X protein (HBx) have similarities with the sequences of a host cellular microRNA (miRNA), miR129-5p. HBx inhibits miR129-5p function, resulting in increased expression of ZBTB20, a target gene of miR129-5p.

Starting a new search, please wait ...