Detail Information

Basic Information:


  VIRBase ID:  

HHID00026385

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1343-3p:           SESN3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1343-3p SESN3
miRBase
Accession/Entrez ID		 MIMAT0019776 143686
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SEST3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1343-3p
rs1030024806 chr11:34941897    C/T
rs1228966720 chr11:34941904    T/G
rs1335261302 chr11:34941900    G/A
rs568333985 chr11:34941898    C/G
rs748356067 chr11:34941908    G/A
rs950497159 chr11:34941907    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SESN3
chr11:94907804(-) A-I      intronic
chr11:94943099(-) A-I      intronic
chr11:94940216(-) A-I      intronic
chr11:94907817(-) A-I      intronic
chr11:94907812(-) A-I      intronic
chr11:94939997(-) A-I      intronic
chr11:94907745(-) A-I      intronic
chr11:94907870(-) A-I      intronic
chr11:94960478(-) A-I      intronic
chr11:94907740(-) A-I      intronic
chr11:94960472(-) A-I      intronic
chr11:94916770(-) A-I      intronic
chr11:94951904(-) A-I      intronic
chr11:94916763(-) A-I      intronic
chr11:94950716(-) A-I      intronic
chr11:94954216(-) A-I      intronic
chr11:94950813(-) A-I      intronic
chr11:94950635(-) A-I      intronic
chr11:94951978(-) A-I      intronic
chr11:94950632(-) A-I      intronic
chr11:94960552(-) A-I      intronic
chr11:94960481(-) A-I      intronic
chr11:94908494(-) A-I      intronic
chr11:94940098(-) A-I      intronic
chr11:94951982(-) A-I      intronic
chr11:94907831(-) A-I      intronic
chr11:94954446(-) A-I      intronic
chr11:94907825(-) A-I      intronic
chr11:94950603(-) A-I      intronic
chr11:94951888(-) A-I      intronic
chr11:94956576(-) A-I      intronic
chr11:94954360(-) A-I      intronic
chr11:94951887(-) A-I      intronic
chr11:94950650(-) A-I      intronic
chr11:94940038(-) A-I      intronic
chr11:94951953(-) A-I      intronic
chr11:94942993(-) A-I      intronic
chr11:94908445(-) A-I      intronic
chr11:94907828(-) A-I      intronic
chr11:94907759(-) A-I      intronic
chr11:94908311(-) A-I      intronic
chr11:94940215(-) A-I      intronic
chr11:94908459(-) A-I      intronic
chr11:94907823(-) A-I      intronic
chr11:94960421(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SESN3
chr11:94898907-94898908(-) m6A 3'UTR       26404942
chr11:94898924-94898925(-) m6A 3'UTR       26404942
chr11:94898939-94898940(-) m6A 3'UTR       26404942
chr11:94901820-94901821(-) m6A 3'UTR       24284625//27773535
chr11:94901892-94901893(-) m6A 3'UTR       24284625//24981863//27773535
chr11:94901963-94901964(-) m6A 3'UTR       24284625//24981863//27773535
chr11:94901968-94901969(-) m6A 3'UTR       24284625//24981863//27773535
chr11:94902259-94902260(-) m6A 3'UTR       24981863
chr11:94902266-94902267(-) m6A 3'UTR       24981863
chr11:94906363-94906364(-) m6A 3'UTR       24981863//27773535//22608085
chr11:94906381-94906382(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr11:94906460-94906461(-) m6A CDS       26404942//22608085
chr11:94908673-94908674(-) m6A CDS       22608085
chr11:94917707-94917708(-) m6A CDS       24981863
chr11:94918643-94918644(-) m6A CDS       24284625//22608085
chr11:94918653-94918654(-) m6A CDS       24284625//22608085
chr11:94923014-94923015(-) m6A CDS//intron       24284625//22608085
chr11:94923064-94923065(-) m6A CDS//intron       24284625
chr11:94923090-94923091(-) m6A CDS//intron       24284625
chr11:94964019-94964020(-) m6A CDS//intron       27773536
chr11:94964066-94964067(-) m6A 5'UTR//intron       27371828//27773536
chr11:94964099-94964100(-) m6A 5'UTR//intron       27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1343-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SESN3
Exosome Blood     -
Nucleoplasm K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1343-3p
Interactor2: SESN3

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Downregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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