Detail Information

Basic Information:


  VIRBase ID:  

HHID00026357

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1343-3p:           SLC25A28:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1343-3p SLC25A28
miRBase
Accession/Entrez ID		 MIMAT0019776 81894
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MFRN2//MRS3/4//MRS4L//NPD016

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1343-3p
rs1030024806 chr11:34941897    C/T
rs1228966720 chr11:34941904    T/G
rs1335261302 chr11:34941900    G/A
rs568333985 chr11:34941898    C/G
rs748356067 chr11:34941908    G/A
rs950497159 chr11:34941907    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLC25A28
chr10:101370339-101370340(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr10:101370791-101370792(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:101370807-101370808(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:101370841-101370842(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:101371071-101371072(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:101372310-101372311(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr10:101373296-101373297(-) m6A exon//intron       24284625
chr10:101373500-101373501(-) m6A CDS//exon//intron       24209618//24981863//26404942//22608085
chr10:101379907-101379908(-) m6A CDS//exon//intron       24284625//24209618//27371828
chr10:101379919-101379920(-) m6A CDS//exon//intron       24284625//24209618//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1343-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SLC25A28
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1343-3p
Interactor2: SLC25A28

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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