Detail Information

Basic Information:


  VIRBase ID:  

HHID00026355

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1343-3p:           APOL3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1343-3p APOL3
miRBase
Accession/Entrez ID		 MIMAT0019776 80833
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - apoL-III//APOLIII//CG121//CG12_1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1343-3p
rs1030024806 chr11:34941897    C/T
rs1228966720 chr11:34941904    T/G
rs1335261302 chr11:34941900    G/A
rs568333985 chr11:34941898    C/G
rs748356067 chr11:34941908    G/A
rs950497159 chr11:34941907    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR APOL3
chr22:36548946(-) A-I      intronic
chr22:36556045(-) A-I      intronic
chr22:36548953(-) A-I      intronic
chr22:36552310(-) A-I      intronic
chr22:36548900(-) A-I      intronic
chr22:36548913(-) A-I      intronic
chr22:36552315(-) A-I      intronic
chr22:36552313(-) A-I      intronic
chr22:36556106(-) A-I      intronic
chr22:36547780(-) A-I      intronic
chr22:36549035(-) A-I      intronic
chr22:36549027(-) A-I      intronic
chr22:36546055(-) A-I      intronic
chr22:36552341(-) A-I      intronic
chr22:36546141(-) A-I      intronic
chr22:36546059(-) A-I      intronic
chr22:36556132(-) A-I      intronic
chr22:36546846(-) A-I      intronic
chr22:36552254(-) A-I      intronic
chr22:36546725(-) A-I      intronic
chr22:36556189(-) A-I      intronic
chr22:36556173(-) A-I      intronic
chr22:36549076(-) A-I      intronic
chr22:36556110(-) A-I      intronic
chr22:36556107(-) A-I      intronic
chr22:36548952(-) A-I      intronic
chr22:36549038(-) A-I      intronic
chr22:36547889(-) A-I      intronic
chr22:36546811(-) A-I      intronic
chr22:36553930(-) A-I      intronic
chr22:36548994(-) A-I      intronic
chr22:36548991(-) A-I      intronic
chr22:36556026(-) A-I      intronic
chr22:36547818(-) A-I      intronic
chr22:36547799(-) A-I      intronic
chr22:36546106(-) A-I      intronic
chr22:36548945(-) A-I      intronic
chr22:36554678(-) A-I      intronic
chr22:36547782(-) A-I      intronic
chr22:36556109(-) A-I      intronic
chr22:36556068(-) A-I      intronic
chr22:36546887(-) A-I      intronic
chr22:36556108(-) A-I      intronic
chr22:36552271(-) A-I      intronic
chr22:36556158(-) A-I      intronic
chr22:36556067(-) A-I      intronic
chr22:36556032(-) A-I      intronic
chr22:36554772(-) A-I      intronic
chr22:36548922(-) A-I      intronic
chr22:36554700(-) A-I      intronic
chr22:36545957(-) A-I      intronic
chr22:36545969(-) A-I      intronic
chr22:36546090(-) A-I      intronic
chr22:36546900(-) A-I      intronic
chr22:36546149(-) A-I      intronic
chr22:36548891(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED APOL3
chr22:36547782(-) A-G intron -    22484847
chr22:36547818(-) A-G intron -    22484847
chr22:36547889(-) A-G intron -    22484847
chr22:36556002(-) A-G intron -    22484847
chr22:36556058(-) A-G intron -    22484847
chr22:36556067(-) A-G intron -    22484847
chr22:36556068(-) A-G intron -    22484847
chr22:36556110(-) A-G intron -    22484847
chr22:36556173(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase APOL3
chr22:36536392-36536393(-) m6A 3'UTR       28052920
chr22:36536454-36536455(-) m6A 3'UTR       28052920
chr22:36536484-36536485(-) m6A 3'UTR       28052920
chr22:36536518-36536519(-) m6A 3'UTR       28052920
chr22:36536532-36536533(-) m6A 3'UTR       28052920
chr22:36536554-36536555(-) m6A 3'UTR       28052920
chr22:36536560-36536561(-) m6A 3'UTR       28052920
chr22:36536577-36536578(-) m6A 3'UTR       28052920
chr22:36536624-36536625(-) m6A 3'UTR       -
chr22:36536849-36536850(-) m6A 3'UTR       28052920//27371828
chr22:36536871-36536872(-) m6A 3'UTR       28052920//27371828
chr22:36536932-36536933(-) m6A 3'UTR       28052920//27371828
chr22:36536978-36536979(-) m6A 3'UTR       28052920
chr22:36537019-36537020(-) m6A 3'UTR       28052920
chr22:36537240-36537241(-) m6A 3'UTR       27371828
chr22:36537588-36537589(-) m6A 3'UTR//CDS       28052920//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1343-3p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
APOL3
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1343-3p
Interactor2: APOL3

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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