Detail Information

Basic Information:


  VIRBase ID:  

HHID00026201

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3614-5p:           SUMF1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3614-5p SUMF1
miRBase
Accession/Entrez ID		 MIMAT0017992 285362
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AAPA3037//FGE//UNQ3037

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3614-5p
rs1276310586 chr17:56891320    G/A
rs1422621595 chr17:56891335    C/A
rs1422621595 chr17:56891335    C/G
rs533715139 chr17:56891339    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SUMF1
chr3:4484876(-) A-I      intronic
chr3:4484959(-) A-I      intronic
chr3:4485337(-) A-I      intronic
chr3:4485354(-) A-I      intronic
chr3:4454853(-) A-I      intronic
chr3:3750700(-) A-I      intronic
chr3:4457396(-) A-I      intronic
chr3:3750724(-) A-I      intronic
chr3:3750725(-) A-I      intronic
chr3:3750728(-) A-I      intronic
chr3:4454858(-) A-I      intronic
chr3:4480973(-) A-I      intronic
chr3:4454866(-) A-I      intronic
chr3:4487302(-) A-I      intronic
chr3:4487304(-) A-I      intronic
chr3:4497292(-) A-I      intronic
chr3:4497293(-) A-I      intronic
chr3:4504931(-) A-I      intronic
chr3:4457397(-) A-I      intronic
chr3:4485328(-) A-I      intronic
chr3:4455685(-) A-I      intronic
chr3:4485327(-) A-I      intronic
chr3:4455640(-) A-I      intronic
chr3:4455821(-) A-I      intronic
chr3:4457314(-) A-I      intronic
chr3:3770069(-) A-I      intronic
chr3:4454821(-) A-I      intronic
chr3:4457348(-) A-I      intronic
chr3:4446379(-) A-I      intronic
chr3:4446348(-) A-I      intronic
chr3:4457349(-) A-I      intronic
chr3:4479406(-) A-I      intronic
chr3:4480934(-) A-I      intronic
chr3:4404497(-) A-I      intronic
chr3:4418512(-) A-I      intronic
chr3:4481115(-) A-I      intronic
chr3:4481838(-) A-I      intronic
chr3:4484843(-) A-I      intronic
chr3:4484850(-) A-I      intronic
chr3:4484955(-) A-I      intronic
chr3:4454916(-) A-I      intronic
chr3:4346866(-) A-I      intronic
chr3:4502588(-) A-I      intronic
chr3:4479378(-) A-I      intronic
chr3:4446194(-) A-I      intronic
chr3:4446198(-) A-I      intronic
chr3:4447168(-) A-I      intronic
chr3:4456829(-) A-I      intronic
chr3:4455686(-) A-I      intronic
chr3:4479615(-) A-I      intronic
chr3:4479579(-) A-I      intronic
chr3:4456848(-) A-I      intronic
chr3:4484840(-) A-I      intronic
chr3:4479388(-) A-I      intronic
chr3:4454396(-) A-I      intronic
chr3:4454833(-) A-I      intronic
chr3:4446191(-) A-I      intronic
chr3:4484788(-) A-I      intronic
chr3:4479541(-) A-I      intronic
chr3:4349503(-) A-I      intronic
chr3:4479523(-) A-I      intronic
chr3:4487146(-) A-I      intronic
chr3:4479540(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SUMF1
chr3:4446191(-) A-G intron -    22484847
chr3:4446194(-) A-G intron -    22484847
chr3:4446198(-) A-G intron -    22484847
chr3:4447168(-) A-G intron -    22484847
chr3:4454833(-) A-G intron -    22484847
chr3:4454962(-) A-G intron -    22484847
chr3:4454965(-) A-G intron -    22484847
chr3:4456829(-) A-G intron -    22484847
chr3:4456848(-) A-G intron -    22484847
chr3:4479388(-) A-G intron -    22484847
chr3:4479507(-) A-G intron -    22484847
chr3:4479523(-) A-G intron -    22484847
chr3:4479538(-) A-G intron -    22484847
chr3:4479540(-) A-G intron -    22484847
chr3:4479541(-) A-G intron -    22484847
chr3:4479579(-) A-G intron -    22484847
chr3:4479615(-) A-G intron -    22484847
chr3:4480936(-) C-T intron -    22484847
chr3:4484766(-) A-G intron -    22484847
chr3:4484840(-) A-G intron -    22484847
chr3:4484930(-) A-G intron -    22484847
chr3:4484955(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SUMF1
chr3:3841411-3841412(-) m6A exon//intron       24209618
chr3:3841418-3841419(-) m6A exon//intron       24209618
chr3:3841493-3841494(-) m6A exon//intron       24209618
chr3:3841563-3841564(-) m6A exon//intron       24209618//25456834
chr3:3842533-3842534(-) m6A exon//intron       24209618//25456834
chr3:4403564-4403565(-) m6A 3'UTR//intron       27773535
chr3:4403676-4403677(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr3:4403689-4403690(-) m6A 3'UTR//intron       24284625//24981863//27773535//22608085
chr3:4403759-4403760(-) m6A 3'UTR//intron       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr3:4403831-4403832(-) m6A CDS//intron       24284625//24981863//27773535//27371828//22608085
chr3:4403897-4403898(-) m6A CDS//intron       24981863
chr3:4508933-4508934(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3614-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SUMF1
Chromatin K562 cells     -
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3614-5p
Interactor2: SUMF1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Downregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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