Detail Information

Basic Information:


  VIRBase ID:  

HHID00026192

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3614-5p:           TTC39B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3614-5p TTC39B
miRBase
Accession/Entrez ID		 MIMAT0017992 158219
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C9orf52

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3614-5p
rs1276310586 chr17:56891320    G/A
rs1422621595 chr17:56891335    C/A
rs1422621595 chr17:56891335    C/G
rs533715139 chr17:56891339    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR TTC39B
chr9:15303726(-) A-I      intronic
chr9:15303706(-) A-I      intronic
chr9:15303703(-) A-I      intronic
chr9:15257612(-) A-I      intronic
chr9:15257585(-) A-I      intronic
chr9:15242481(-) A-I      intronic
chr9:15178489(-) A-I      intronic
chr9:15262329(-) A-I      intronic
chr9:15302103(-) A-I      intronic
chr9:15301707(-) A-I      intronic
chr9:15301590(-) A-I      intronic
chr9:15301561(-) A-I      intronic
chr9:15178490(-) A-I      intronic
chr9:15261289(-) A-I      intronic
chr9:15262324(-) A-I      intronic
chr9:15301508(-) A-I      intronic
chr9:15257549(-) A-I      intronic
chr9:15178547(-) A-I      intronic
chr9:15178535(-) A-I      intronic
chr9:15178516(-) A-I      intronic
chr9:15301509(-) A-I      intronic
chr9:15178326(-) A-I      intronic
chr9:15178134(-) A-I      intronic
chr9:15178070(-) A-I      intronic
chr9:15178006(-) A-I      intronic
chr9:15257605(-) A-I      intronic
chr9:15303665(-) A-I      intronic
chr9:15303811(-) A-I      intronic
chr9:15257609(-) A-I      intronic
chr9:15303738(-) A-I      intronic
chr9:15257641(-) A-I      intronic
chr9:15302567(-) A-I      intronic
chr9:15302612(-) A-I      intronic
chr9:15303431(-) A-I      intronic
chr9:15302104(-) A-I      intronic
chr9:15303445(-) A-I      intronic
chr9:15302158(-) A-I      intronic
chr9:15302116(-) A-I      intronic
chr9:15302117(-) A-I      intronic
chr9:15302118(-) A-I      intronic
chr9:15302141(-) A-I      intronic
chr9:15303794(-) A-I      intronic
chr9:15261374(-) A-I      intronic
chr9:15242323(-) A-I      intronic
chr9:15261259(-) A-I      intronic
chr9:15281813(-) A-I      intronic
chr9:15303057(-) A-I      intronic
chr9:15301691(-) A-I      intronic
chr9:15302212(-) A-I      intronic
chr9:15178430(-) A-I      intronic
chr9:15303812(-) A-I      intronic
chr9:15296923(-) A-I      intronic
chr9:15178452(-) A-I      intronic
chr9:15302261(-) A-I      intronic
chr9:15178312(-) A-I      intronic
chr9:15303544(-) A-I      intronic
chr9:15301589(-) A-I      intronic
chr9:15303471(-) A-I      intronic
chr9:15303466(-) A-I      intronic
chr9:15303534(-) A-I      intronic
chr9:15178511(-) A-I      intronic
chr9:15178551(-) A-I      intronic
chr9:15261232(-) A-I      intronic
chr9:15202588(-) A-I      intronic
chr9:15178462(-) A-I      intronic
chr9:15303508(-) A-I      intronic
chr9:15178521(-) A-I      intronic
chr9:15301710(-) A-I      intronic
chr9:15302720(-) A-I      intronic
chr9:15202624(-) A-I      intronic
chr9:15215433(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED TTC39B
chr9:15298396(-) A-I intron -    21960545
chr9:15301632(-) A-I intron -    21960545
chr9:15215433(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TTC39B
chr9:15171469-15171470(-) m6A 3'UTR       24981863//27773535//22608085
chr9:15171506-15171507(-) m6A 3'UTR       24981863//27773535//22608085
chr9:15171512-15171513(-) m6A 3'UTR       24981863//27773535//22608085
chr9:15171523-15171524(-) m6A 3'UTR       24981863//27773535//22608085
chr9:15171536-15171537(-) m6A 3'UTR       24981863//27773535
chr9:15171909-15171910(-) m6A 3'UTR//exon       24981863//22608085
chr9:15171917-15171918(-) m6A 3'UTR//exon       24981863//22608085
chr9:15172010-15172011(-) m6A 3'UTR//exon       24981863//22608085
chr9:15172031-15172032(-) m6A CDS//exon       24981863//22608085
chr9:15172073-15172074(-) m6A CDS//exon       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3614-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
TTC39B
Cytosol HCC cell line (HepG2)     -
Exosome Blood     -
Nucleus HCC cell line (HepG2)     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3614-5p
Interactor2: TTC39B

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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