Detail Information

Basic Information:


  VIRBase ID:  

HHID00026183

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3614-5p:           SPIN4:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3614-5p SPIN4
miRBase
Accession/Entrez ID		 MIMAT0017992 139886
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - TDRD28

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3614-5p
rs1276310586 chr17:56891320    G/A
rs1422621595 chr17:56891335    C/A
rs1422621595 chr17:56891335    C/G
rs533715139 chr17:56891339    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SPIN4
chrX:62569647-62569648(-) m6A 3'UTR       27773535
chrX:62569685-62569686(-) m6A 3'UTR       27773535
chrX:62569956-62569957(-) m6A CDS       24981863//27773535//22608085
chrX:62570052-62570053(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:62570128-62570129(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chrX:62570308-62570309(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:62570434-62570435(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:62570440-62570441(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chrX:62570582-62570583(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chrX:62570811-62570812(-) m6A 5'UTR       24284625//24981863//27371828//22608085
chrX:62570850-62570851(-) m6A 5'UTR       24284625//25456834//24981863//27371828//22608085
chrX:62570987-62570988(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chrX:62571023-62571024(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chrX:62571153-62571154(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chrX:62571164-62571165(-) m6A 5'UTR       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3614-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
SPIN4
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3614-5p
Interactor2: SPIN4

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Downregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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