Detail Information

Basic Information:


  VIRBase ID:  

HHID00026176

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3614-5p:           BATF2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3614-5p BATF2
miRBase
Accession/Entrez ID		 MIMAT0017992 116071
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SARI

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3614-5p
rs1276310586 chr17:56891320    G/A
rs1422621595 chr17:56891335    C/A
rs1422621595 chr17:56891335    C/G
rs533715139 chr17:56891339    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BATF2
chr11:64761469(-) A-I      intronic
chr11:64758360(-) A-I      intronic
chr11:64760205(-) A-I      intronic
chr11:64758359(-) A-I      intronic
chr11:64760216(-) A-I      intronic
chr11:64760266(-) A-I      intronic
chr11:64761383(-) A-I      intronic
chr11:64761406(-) A-I      intronic
chr11:64761543(-) A-I      intronic
chr11:64761392(-) A-I      intronic
chr11:64760211(-) A-I      intronic
chr11:64760302(-) A-I      intronic
chr11:64761388(-) A-I      intronic
chr11:64760076(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BATF2
chr11:64755543-64755544(-) m6A 3'UTR//exon       27773535
chr11:64755574-64755575(-) m6A 3'UTR//exon       25456834//27773535
chr11:64755669-64755670(-) m6A 3'UTR//exon       25456834
chr11:64755703-64755704(-) m6A 3'UTR//exon       25456834
chr11:64755822-64755823(-) m6A 3'UTR//exon       27773535
chr11:64756125-64756126(-) m6A 3'UTR//exon       27371828
chr11:64756930-64756931(-) m6A CDS//exon       24981863//27371828
chr11:64757049-64757050(-) m6A CDS//exon       24981863//27371828//27773536
chr11:64757086-64757087(-) m6A CDS//exon       25456834//27371828//27773536
chr11:64757123-64757124(-) m6A CDS//exon       25456834//27371828//27773536
chr11:64757199-64757200(-) m6A 5'UTR//CDS//exon       25456834//27371828
chr11:64757261-64757262(-) m6A 5'UTR//CDS//exon       27371828//27773536
chr11:64757363-64757364(-) m6A exon//intron       27371828
chr11:64757414-64757415(-) m6A exon//intron       -
chr11:64757967-64757968(-) m6A exon//intron       27371828
chr11:64761941-64761942(-) m6A CDS       27371828
chr11:64761980-64761981(-) m6A CDS       25456834//27371828
chr11:64764349-64764350(-) m6A CDS       25456834//27371828
chr11:64764410-64764411(-) m6A 5'UTR       27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3614-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
BATF2
Chromatin K562 cells     -
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3614-5p
Interactor2: BATF2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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