Detail Information

Basic Information:


  VIRBase ID:  

HHID00026010

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3182:           SLFN5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3182 SLFN5
miRBase
Accession/Entrez ID		 MIMAT0015062 162394
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3182
rs1367036983 chr16:83508358    G/A
rs564683390 chr16:83508360    G/A
rs923654044 chr16:83508365    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SLFN5
chr17:33590682(+) A-I      intronic
chr17:33590643(+) A-I      intronic
chr17:33590333(+) A-I      intronic
chr17:33590229(+) A-I      intronic
chr17:33589808(+) A-I      intronic
chr17:33590295(+) A-I      intronic
chr17:33590699(+) A-I      intronic
chr17:33590291(+) A-I      intronic
chr17:33590727(+) A-I      intronic
chr17:33590691(+) A-I      intronic
chr17:33590711(+) A-I      intronic
chr17:33590695(+) A-I      intronic
chr17:33590683(+) A-I      intronic
chr17:33590692(+) A-I      intronic
chr17:33590666(+) A-I      intronic
chr17:33589727(+) A-I      intronic
chr17:33589320(+) A-I      intronic
chr17:33589680(+) A-I      intronic
chr17:33578813(+) A-I      intronic
chr17:33589696(+) A-I      intronic
chr17:33571791(+) A-I      intronic
chr17:33589870(+) A-I      intronic
chr17:33571786(+) A-I      intronic
chr17:33589798(+) A-I      intronic
chr17:33590754(+) A-I      intronic
chr17:33590738(+) A-I      intronic
chr17:33578684(+) A-I      intronic
chr17:33590299(+) A-I      intronic
chr17:33578826(+) A-I      intronic
chr17:33590181(+) A-I      intronic
chr17:33578703(+) A-I      intronic
chr17:33578953(+) A-I      intronic
chr17:33571689(+) A-I      intronic
chr17:33590770(+) A-I      intronic
chr17:33589252(+) A-I      intronic
chr17:33579356(+) A-I      intronic
chr17:33588918(+) A-I      intronic
chr17:33590772(+) A-I      intronic
chr17:33588751(+) A-I      intronic
chr17:33588798(+) A-I      intronic
chr17:33588427(+) A-I      intronic
chr17:33589756(+) A-I      intronic
chr17:33590430(+) A-I      intronic
chr17:33578685(+) A-I      intronic
chr17:33590819(+) A-I      intronic
chr17:33590219(+) A-I      intronic
chr17:33589815(+) A-I      intronic
chr17:33578850(+) A-I      intronic
chr17:33578756(+) A-I      intronic
chr17:33590686(+) A-I      intronic
chr17:33589691(+) A-I      intronic
chr17:33590757(+) A-I      intronic
chr17:33588872(+) A-I      intronic
chr17:33588472(+) A-I      intronic
chr17:33590843(+) A-I      intronic
chr17:33590230(+) A-I      intronic
chr17:33579376(+) A-I      intronic
chr17:33588492(+) A-I      intronic
chr17:33590777(+) A-I      intronic
chr17:33588974(+) A-I      intronic
chr17:33571881(+) A-I      intronic
chr17:33588597(+) A-I      intronic
chr17:33590359(+) A-I      intronic
chr17:33588972(+) A-I      intronic
chr17:33590818(+) A-I      intronic
chr17:33590440(+) A-I      intronic
chr17:33590684(+) A-I      intronic
chr17:33590250(+) A-I      intronic
chr17:33588898(+) A-I      intronic
chr17:33588794(+) A-I      intronic
chr17:33588609(+) A-I      intronic
chr17:33589242(+) A-I      intronic
chr17:33588795(+) A-I      intronic
chr17:33588775(+) A-I      intronic
chr17:33589681(+) A-I      intronic
chr17:33590254(+) A-I      intronic
chr17:33588834(+) A-I      intronic
chr17:33590774(+) A-I      intronic
chr17:33579351(+) A-I      intronic
chr17:33590840(+) A-I      intronic
chr17:33589858(+) A-I      intronic
chr17:33588830(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SLFN5
chr17:33588472(+) A-G intron -    22484847
chr17:33590254(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SLFN5
chr17:33570101-33570102(+) m6A 5'UTR       -
chr17:33570153-33570154(+) m6A 5'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33585673-33585674(+) m6A 5'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33585737-33585738(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33585781-33585782(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:33585803-33585804(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:33585822-33585823(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085
chr17:33585899-33585900(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33585986-33585987(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33586016-33586017(+) m6A CDS       24284625//24209618//24981863//22608085
chr17:33586075-33586076(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085
chr17:33586129-33586130(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085
chr17:33586135-33586136(+) m6A CDS       24284625//24209618//24981863//26404942//22575960//22608085
chr17:33586266-33586267(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33586337-33586338(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33586411-33586412(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33586448-33586449(+) m6A CDS       24284625//24209618//24981863//22575960//22608085
chr17:33586658-33586659(+) m6A CDS       24284625//24209618//24981863//26404942//22608085
chr17:33586671-33586672(+) m6A CDS       24284625//24209618//24981863
chr17:33586693-33586694(+) m6A CDS       24284625//24209618//24981863
chr17:33591210-33591211(+) m6A CDS//intron       24284625//24209618//24981863//22608085
chr17:33591247-33591248(+) m6A CDS//intron       24284625//24981863//22608085
chr17:33591268-33591269(+) m6A CDS//intron       24284625//24981863//22608085
chr17:33591276-33591277(+) m6A CDS//intron       24284625//24981863//22608085
chr17:33591402-33591403(+) m6A CDS//intron       24284625//24981863
chr17:33591723-33591724(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33591739-33591740(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33591762-33591763(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33591773-33591774(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33591815-33591816(+) m6A CDS//intron       24284625//22575960
chr17:33591868-33591869(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33591897-33591898(+) m6A CDS//intron       24284625//24981863//22575960
chr17:33592104-33592105(+) m6A CDS       24284625//24209618//24981863//22575960
chr17:33592130-33592131(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960
chr17:33592143-33592144(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960
chr17:33592153-33592154(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960
chr17:33592209-33592210(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960
chr17:33592241-33592242(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22575960
chr17:33592281-33592282(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863
chr17:33592292-33592293(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863
chr17:33592332-33592333(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//22608085
chr17:33592471-33592472(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592518-33592519(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592524-33592525(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592644-33592645(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592675-33592676(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592758-33592759(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960
chr17:33592876-33592877(+) m6A 3'UTR//CDS       24284625//24209618//24981863//22575960//22608085
chr17:33592913-33592914(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33592928-33592929(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33592964-33592965(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33592978-33592979(+) m6A 3'UTR       24284625//24209618//24981863//22575960//22608085
chr17:33593073-33593074(+) m6A 3'UTR       24284625//24209618//24981863
chr17:33593100-33593101(+) m6A 3'UTR       24284625//24209618//24981863
chr17:33593144-33593145(+) m6A 3'UTR       24284625//24981863
chr17:33593152-33593153(+) m6A 3'UTR       24284625//24981863
chr17:33593280-33593281(+) m6A 3'UTR       24284625
chr17:33593314-33593315(+) m6A 3'UTR       24284625
chr17:33594757-33594758(+) m6A 3'UTR       24981863
chr17:33595353-33595354(+) m6A 3'UTR       24981863
chr17:33595402-33595403(+) m6A 3'UTR       24981863
chr17:33595433-33595434(+) m6A 3'UTR       24981863
chr17:33595440-33595441(+) m6A 3'UTR       24981863
chr17:33596511-33596512(+) m6A 3'UTR       24981863
chr17:33596547-33596548(+) m6A 3'UTR       24981863
chr17:33596618-33596619(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3182
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
SLFN5
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3182
Interactor2: SLFN5

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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