Detail Information

Basic Information:


  VIRBase ID:  

HHID00025873

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3182:           PML:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3182 PML
miRBase
Accession/Entrez ID		 MIMAT0015062 5371
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MYL//PP8675//RNF71//TRIM19

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3182
rs1367036983 chr16:83508358    G/A
rs564683390 chr16:83508360    G/A
rs923654044 chr16:83508365    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PML
chr15:74295589(+) A-I      intronic
chr15:74295619(+) A-I      intronic
chr15:74295620(+) A-I      intronic
chr15:74295626(+) A-I      intronic
chr15:74296482(+) A-I      intronic
chr15:74296514(+) A-I      intronic
chr15:74298714(+) A-I      intronic
chr15:74298689(+) A-I      intronic
chr15:74298687(+) A-I      intronic
chr15:74298682(+) A-I      intronic
chr15:74296832(+) A-I      intronic
chr15:74301030(+) A-I      intronic
chr15:74296826(+) A-I      intronic
chr15:74302045(+) A-I      intronic
chr15:74302052(+) A-I      intronic
chr15:74306799(+) A-I      intronic
chr15:74306944(+) A-I      intronic
chr15:74306945(+) A-I      intronic
chr15:74301005(+) A-I      intronic
chr15:74306996(+) A-I      intronic
chr15:74307035(+) A-I      intronic
chr15:74321710(+) A-I      intronic
chr15:74321858(+) A-I      intronic
chr15:74321886(+) A-I      intronic
chr15:74322879(+) A-I      intronic
chr15:74323639(+) A-I      intronic
chr15:74294251(+) A-I      intronic
chr15:74295006(+) A-I      intronic
chr15:74295234(+) A-I      intronic
chr15:74323671(+) A-I      intronic
chr15:74323679(+) A-I      intronic
chr15:74323725(+) A-I      intronic
chr15:74323732(+) A-I      intronic
chr15:74292174(+) A-I      intronic
chr15:74323740(+) A-I      intronic
chr15:74295764(+) A-I      intronic
chr15:74294124(+) A-I      intronic
chr15:74294271(+) A-I      intronic
chr15:74296845(+) A-I      intronic
chr15:74294885(+) A-I      intronic
chr15:74310261(+) A-I      intronic
chr15:74298652(+) A-I      intronic
chr15:74309787(+) A-I      intronic
chr15:74306815(+) A-I      intronic
chr15:74321854(+) A-I      intronic
chr15:74306777(+) A-I      intronic
chr15:74300933(+) A-I      intronic
chr15:74302721(+) A-I      intronic
chr15:74323680(+) A-I      intronic
chr15:74308560(+) A-I      intronic
chr15:74294290(+) A-I      intronic
chr15:74307068(+) A-I      intronic
chr15:74322944(+) A-I      intronic
chr15:74323715(+) A-I      intronic
chr15:74317202(+) A-I      Syn:Ala->Ala
chr15:74295408(+) A-I      intronic
chr15:74321834(+) A-I      intronic
chr15:74322869(+) A-I      intronic
chr15:74294194(+) A-I      intronic
chr15:74295056(+) A-I      intronic
chr15:74323714(+) A-I      intronic
chr15:74302778(+) A-I      intronic
chr15:74302019(+) A-I      intronic
chr15:74309843(+) A-I      intronic
chr15:74295291(+) A-I      intronic
chr15:74294125(+) A-I      intronic
chr15:74322883(+) A-I      intronic
chr15:74309812(+) A-I      intronic
chr15:74296502(+) A-I      intronic
chr15:74321920(+) A-I      intronic
chr15:74294846(+) A-I      intronic
chr15:74322870(+) A-I      intronic
chr15:74295289(+) A-I      intronic
chr15:74293798(+) A-I      intronic
chr15:74294158(+) A-I      intronic
chr15:74302422(+) A-I      intronic
chr15:74295416(+) A-I      intronic
chr15:74293822(+) A-I      intronic
chr15:74302424(+) A-I      intronic
chr15:74295212(+) A-I      intronic
chr15:74292830(+) A-I      intronic
chr15:74295218(+) A-I      intronic
chr15:74294224(+) A-I      intronic
chr15:74296515(+) A-I      intronic
chr15:74322911(+) A-I      intronic
chr15:74302784(+) A-I      intronic
chr15:74298476(+) A-I      intronic
chr15:74321845(+) A-I      intronic
chr15:74295233(+) A-I      intronic
chr15:74302448(+) A-I      intronic
chr15:74323741(+) A-I      intronic
chr15:74295047(+) A-I      intronic
chr15:74296778(+) A-I      intronic
chr15:74322891(+) A-I      intronic
chr15:74310680(+) A-I      intronic
chr15:74295290(+) A-I      intronic
chr15:74309828(+) A-I      intronic
chr15:74295652(+) A-I      intronic
chr15:74314373(+) A-I      intronic
chr15:74293820(+) A-I      intronic
chr15:74309835(+) A-I      intronic
chr15:74302455(+) A-I      intronic
chr15:74302051(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PML
chr15:74317202(+) A-I exon CDS    19478186
chr15:74317854(+) A-I intron -    19478186
chr15:74317860(+) A-I intron -    19478186
chr15:74317861(+) A-I intron -    19478186
chr15:74319173(+) A-I intron -    22327324
chr15:74319236(+) A-I intron -    22327324
chr15:74319668(+) A-I intron -    21960545   //22327324
chr15:74319733(+) A-I intron -    22327324
chr15:74319734(+) A-I intron -    22327324
chr15:74319764(+) A-I intron -    22327324
chr15:74319794(+) A-I intron -    22327324
chr15:74319813(+) A-I intron -    22327324
chr15:74319851(+) A-I intron -    22327324
chr15:74319236(+) A-G intron -    21725310   //22484847
chr15:74337678(+) A-C intron -    21725310
chr15:74318562(+) A-G intron -    22484847
chr15:74319173(+) A-G intron -    22484847
chr15:74319268(+) A-G intron -    22484847
chr15:74319638(+) A-G intron -    22484847
chr15:74319668(+) A-G intron -    22484847
chr15:74319728(+) A-G intron -    22484847
chr15:74319732(+) A-G intron -    22484847
chr15:74319733(+) A-G intron -    22484847
chr15:74319734(+) A-G intron -    22484847
chr15:74319764(+) A-G intron -    22484847
chr15:74319770(+) A-G intron -    22484847
chr15:74319773(+) A-G intron -    22484847
chr15:74319786(+) A-G intron -    22484847
chr15:74319794(+) A-G intron -    22484847
chr15:74319813(+) A-G intron -    22484847
chr15:74319851(+) A-G intron -    22484847
chr15:74317854(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PML
chr15:74287054-74287055(+) m6A 5'UTR       24981863
chr15:74287066-74287067(+) m6A 5'UTR       24981863
chr15:74287125-74287126(+) m6A 5'UTR       24284625//24209618//24981863
chr15:74287138-74287139(+) m6A 5'UTR       24284625//24209618//24981863
chr15:74287193-74287194(+) m6A CDS       24284625//24981863
chr15:74287234-74287235(+) m6A CDS       24284625//24981863
chr15:74290764-74290765(+) m6A CDS//exon       -
chr15:74315388-74315389(+) m6A CDS//exon       -
chr15:74315590-74315591(+) m6A CDS//exon       25456834//24981863
chr15:74315605-74315606(+) m6A CDS//exon       25456834//24981863
chr15:74315719-74315720(+) m6A CDS//exon//intron       -
chr15:74317248-74317249(+) m6A CDS//exon       -
chr15:74325541-74325542(+) m6A CDS//exon//intron       24209618
chr15:74325669-74325670(+) m6A CDS//intron       24284625//24209618
chr15:74326851-74326852(+) m6A 3'UTR//CDS//intron       -
chr15:74326866-74326867(+) m6A 3'UTR//CDS//intron       -
chr15:74326898-74326899(+) m6A 3'UTR//CDS//intron       25456834
chr15:74326957-74326958(+) m6A 3'UTR//CDS//intron       25456834
chr15:74327016-74327017(+) m6A 3'UTR//intron       25456834
chr15:74327046-74327047(+) m6A 3'UTR//intron       25456834
chr15:74327455-74327456(+) m6A 3'UTR//intron       -
chr15:74327530-74327531(+) m6A 3'UTR//CDS//intron       -
chr15:74327854-74327855(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22575960
chr15:74327931-74327932(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863//22575960//22608085
chr15:74328127-74328128(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863
chr15:74328155-74328156(+) m6A 3'UTR//CDS//intron       24284625//24209618//25456834//24981863
chr15:74328445-74328446(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr15:74328461-74328462(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr15:74328548-74328549(+) m6A 3'UTR//intron       24284625//24209618//25456834//24981863
chr15:74328676-74328677(+) m6A 3'UTR//intron       24284625
chr15:74328691-74328692(+) m6A 3'UTR//intron       24284625
chr15:74328717-74328718(+) m6A 3'UTR//intron       -
chr15:74328728-74328729(+) m6A 3'UTR//intron       -
chr15:74336756-74336757(+) m6A CDS       24209618//25456834//24981863
chr15:74336777-74336778(+) m6A CDS       24284625//24209618//25456834//24981863
chr15:74336874-74336875(+) m6A CDS       24284625//24209618//25456834//24981863//22575960
chr15:74336882-74336883(+) m6A CDS       24209618//25456834//24981863//22575960
chr15:74336893-74336894(+) m6A CDS       24209618//25456834//24981863//22575960
chr15:74336909-74336910(+) m6A CDS       24209618//25456834//24981863//22575960
chr15:74337824-74337825(+) m6A 3'UTR       25456834
chr15:74337829-74337830(+) m6A 3'UTR       25456834
chr15:74337927-74337928(+) m6A 3'UTR       25456834
chr15:74337933-74337934(+) m6A 3'UTR       25456834
chr15:74338532-74338533(+) m6A 3'UTR       -
chr15:74338540-74338541(+) m6A 3'UTR       -
chr15:74338574-74338575(+) m6A 3'UTR       -
chr15:74338620-74338621(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3182
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
PML
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3182
Interactor2: PML

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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