Detail Information

Basic Information:


  VIRBase ID:  

HHID00025841

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-3182:           GBP3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-3182 GBP3
miRBase
Accession/Entrez ID
MIMAT0015062 2635
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-3182
rs1367036983 chr16:83508358    G/A
rs564683390 chr16:83508360    G/A
rs923654044 chr16:83508365    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR GBP3
chr1:89481375(-) A-I      intronic
chr1:89482530(-) A-I      intronic
chr1:89483645(-) A-I      intronic
chr1:89483680(-) A-I      intronic
chr1:89485109(-) A-I      intronic
chr1:89485144(-) A-I      intronic
chr1:89485153(-) A-I      intronic
chr1:89485148(-) A-I      intronic
chr1:89485915(-) A-I      intronic
chr1:89485914(-) A-I      intronic
chr1:89485256(-) A-I      intronic
chr1:89485189(-) A-I      intronic
chr1:89485165(-) A-I      intronic
chr1:89482002(-) A-I      intronic
chr1:89482078(-) A-I      intronic
chr1:89482133(-) A-I      intronic
chr1:89482513(-) A-I      intronic
chr1:89482522(-) A-I      intronic
chr1:89482531(-) A-I      intronic
chr1:89482336(-) A-I      intronic
chr1:89483559(-) A-I      intronic
chr1:89483748(-) A-I      intronic
chr1:89483527(-) A-I      intronic
chr1:89483577(-) A-I      intronic
chr1:89483593(-) A-I      intronic
chr1:89485147(-) A-I      intronic
chr1:89482363(-) A-I      intronic
chr1:89485068(-) A-I      intronic
chr1:89483558(-) A-I      intronic
chr1:89482446(-) A-I      intronic
chr1:89485136(-) A-I      intronic
chr1:89483758(-) A-I      intronic
chr1:89485039(-) A-I      intronic
chr1:89483640(-) A-I      intronic
chr1:89485751(-) A-I      intronic
chr1:89482537(-) A-I      intronic
chr1:89485040(-) A-I      intronic
chr1:89482396(-) A-I      intronic
chr1:89481956(-) A-I      intronic
chr1:89485083(-) A-I      intronic
chr1:89483654(-) A-I      intronic
chr1:89483650(-) A-I      intronic
chr1:89485074(-) A-I      intronic
chr1:89483557(-) A-I      intronic
chr1:89482021(-) A-I      intronic
chr1:89485917(-) A-I      intronic
chr1:89483710(-) A-I      intronic
chr1:89485146(-) A-I      intronic
chr1:89485757(-) A-I      intronic
chr1:89483729(-) A-I      intronic
chr1:89483667(-) A-I      intronic
chr1:89482552(-) A-I      intronic
chr1:89482015(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED GBP3
chr1:89482531(-) A-I intron -    15342557
chr1:89482552(-) A-I intron -    15342557
chr1:89483527(-) A-I intron -    15342557
chr1:89483557(-) A-I intron -    15342557
chr1:89483558(-) A-I intron -    15342557
chr1:89483559(-) A-I intron -    15342557
chr1:89483577(-) A-I intron -    15342557
chr1:89483593(-) A-I intron -    15342557
chr1:89483640(-) A-I intron -    15342557
chr1:89483650(-) A-I intron -    15342557
chr1:89483654(-) A-I intron -    15342557
chr1:89483667(-) A-I intron -    15342557
chr1:89483710(-) A-I intron -    15342557
chr1:89483729(-) A-I intron -    15342557
chr1:89483748(-) A-I intron -    15342557
chr1:89483758(-) A-I intron -    15342557
chr1:89482015(-) A-G intron -    22484847
chr1:89482537(-) A-G intron -    22484847
chr1:89483650(-) A-G intron -    22484847
chr1:89485039(-) A-G intron -    22484847
chr1:89485040(-) A-G intron -    22484847
chr1:89485083(-) A-G intron -    22484847
chr1:89485136(-) A-G intron -    22484847
chr1:89485146(-) A-G intron -    22484847
chr1:89485147(-) A-G intron -    22484847
chr1:89485827(-) A-G intron -    22484847
chr1:89485835(-) A-G intron -    22484847
chr1:89485836(-) A-G intron -    22484847
chr1:89485862(-) A-G intron -    22484847
chr1:89485870(-) A-G intron -    22484847
chr1:89485886(-) A-G intron -    22484847
chr1:89485917(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase GBP3
chr1:89473405-89473406(-) m6A 3'UTR//exon       27773535
chr1:89473441-89473442(-) m6A 3'UTR//CDS//exon       27773535
chr1:89473456-89473457(-) m6A 3'UTR//CDS//exon       27773535
chr1:89473532-89473533(-) m6A 3'UTR//CDS//exon       24981863//28052920//27773535
chr1:89474546-89474547(-) m6A 3'UTR//intron       24981863//28052920//27773535
chr1:89474565-89474566(-) m6A 3'UTR//intron       24981863//27773535
chr1:89474635-89474636(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr1:89474649-89474650(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr1:89474707-89474708(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr1:89474716-89474717(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr1:89475109-89475110(-) m6A 3'UTR//CDS//exon       24981863//27773535
chr1:89475113-89475114(-) m6A 3'UTR//CDS//exon       27773535//22575960
chr1:89475158-89475159(-) m6A 3'UTR//CDS//exon       27773535
chr1:89486344-89486345(-) m6A CDS//exon//intron       27773535
chr1:89486357-89486358(-) m6A CDS//exon//intron       27773535
chr1:89486405-89486406(-) m6A 5'UTR//exon//intron       24981863//27773535
chr1:89486417-89486418(-) m6A 5'UTR//exon//intron       24981863//27773535
chr1:89488384-89488385(-) m6A 5'UTR//exon       24981863//27773535
chr1:89488398-89488399(-) m6A 5'UTR//exon       24981863//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-3182
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
GBP3
Exosome Blood     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-3182
Interactor2: GBP3

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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