Detail Information

Basic Information:


  VIRBase ID:  

HHID00025328

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-654-3p:           N4BP1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-654-3p N4BP1
miRBase
Accession/Entrez ID
MIMAT0004814 9683
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-654-3p
rs1236276147 chr14:101040288    C/T
rs1273890232 chr14:101040280    ACCATCACCTTTAGAAGC/A
rs1345261848 chr14:101040286    A/G
rs1421723544 chr14:101040280    A/G
rs1337045937 chr14:101040272    G/A
rs1410951502 chr14:101040270    A/G
rs371699284 chr14:101040271    T/C
rs764342883 chr14:101040276    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR N4BP1
chr16:48628556(-) A-I      intronic
chr16:48635651(-) A-I      intronic
chr16:48604949(-) A-I      intronic
chr16:48618603(-) A-I      intronic
chr16:48619880(-) A-I      intronic
chr16:48619896(-) A-I      intronic
chr16:48579692(-) A-I      intronic
chr16:48627710(-) A-I      intronic
chr16:48627789(-) A-I      intronic
chr16:48579937(-) A-I      intronic
chr16:48604840(-) A-I      intronic
chr16:48579674(-) A-I      intronic
chr16:48578972(-) A-I      intronic
chr16:48579389(-) A-I      intronic
chr16:48579402(-) A-I      intronic
chr16:48628534(-) A-I      intronic
chr16:48628430(-) A-I      intronic
chr16:48641984(-) A-I      intronic
chr16:48638244(-) A-I      intronic
chr16:48638243(-) A-I      intronic
chr16:48579013(-) A-I      intronic
chr16:48635859(-) A-I      intronic
chr16:48635714(-) A-I      intronic
chr16:48579045(-) A-I      intronic
chr16:48579122(-) A-I      intronic
chr16:48635673(-) A-I      intronic
chr16:48597171(-) A-I      intronic
chr16:48603346(-) A-I      intronic
chr16:48604422(-) A-I      intronic
chr16:48604506(-) A-I      intronic
chr16:48604507(-) A-I      intronic
chr16:48604818(-) A-I      intronic
chr16:48604819(-) A-I      intronic
chr16:48604896(-) A-I      intronic
chr16:48579143(-) A-I      intronic
chr16:48604906(-) A-I      intronic
chr16:48604916(-) A-I      intronic
chr16:48604934(-) A-I      intronic
chr16:48579359(-) A-I      intronic
chr16:48629138(-) A-I      intronic
chr16:48638205(-) A-I      intronic
chr16:48628509(-) A-I      intronic
chr16:48579259(-) A-I      intronic
chr16:48642187(-) A-I      intronic
chr16:48579069(-) A-I      intronic
chr16:48606812(-) A-I      intronic
chr16:48643122(-) A-I      intronic
chr16:48641901(-) A-I      intronic
chr16:48636782(-) A-I      intronic
chr16:48638407(-) A-I      intronic
chr16:48638342(-) A-I      intronic
chr16:48643074(-) A-I      intronic
chr16:48636799(-) A-I      intronic
chr16:48579426(-) A-I      intronic
chr16:48643043(-) A-I      intronic
chr16:48579450(-) A-I      intronic
chr16:48627718(-) A-I      intronic
chr16:48578930(-) A-I      intronic
chr16:48619382(-) A-I      intronic
chr16:48639040(-) A-I      intronic
chr16:48638217(-) A-I      intronic
chr16:48579365(-) A-I      intronic
chr16:48579771(-) A-I      intronic
chr16:48619376(-) A-I      intronic
chr16:48628351(-) A-I      intronic
chr16:48628403(-) A-I      intronic
chr16:48643004(-) A-I      intronic
chr16:48635746(-) A-I      intronic
chr16:48603431(-) A-I      intronic
chr16:48579745(-) A-I      intronic
chr16:48579079(-) A-I      intronic
chr16:48579481(-) A-I      intronic
chr16:48639214(-) A-I      intronic
chr16:48639012(-) A-I      intronic
chr16:48619844(-) A-I      intronic
chr16:48616945(-) A-I      intronic
chr16:48638352(-) A-I      intronic
chr16:48628386(-) A-I      intronic
chr16:48579293(-) A-I      intronic
chr16:48639082(-) A-I      intronic
chr16:48639011(-) A-I      intronic
chr16:48643031(-) A-I      intronic
chr16:48635883(-) A-I      intronic
chr16:48579488(-) A-I      intronic
chr16:48641869(-) A-I      intronic
chr16:48635875(-) A-I      intronic
chr16:48643010(-) A-I      intronic
chr16:48638264(-) A-I      intronic
chr16:48628363(-) A-I      intronic
chr16:48579148(-) A-I      intronic
chr16:48627813(-) A-I      intronic
chr16:48641905(-) A-I      intronic
chr16:48619289(-) A-I      intronic
chr16:48627830(-) A-I      intronic
chr16:48628542(-) A-I      intronic
chr16:48579855(-) A-I      intronic
chr16:48639137(-) A-I      intronic
chr16:48607497(-) A-I      intronic
chr16:48642000(-) A-I      intronic
chr16:48579367(-) A-I      intronic
chr16:48579843(-) A-I      intronic
chr16:48636121(-) A-I      intronic
chr16:48579354(-) A-I      intronic
chr16:48639136(-) A-I      intronic
chr16:48579932(-) A-I      intronic
chr16:48578905(-) A-I      intronic
chr16:48579403(-) A-I      intronic
chr16:48638355(-) A-I      intronic
chr16:48628485(-) A-I      intronic
chr16:48627801(-) A-I      intronic
chr16:48607337(-) A-I      intronic
chr16:48628406(-) A-I      intronic
chr16:48578978(-) A-I      intronic
chr16:48579774(-) A-I      intronic
chr16:48619801(-) A-I      intronic
chr16:48579113(-) A-I      intronic
chr16:48636861(-) A-I      intronic
chr16:48579905(-) A-I      intronic
chr16:48579734(-) A-I      intronic
chr16:48636842(-) A-I      intronic
chr16:48606838(-) A-I      intronic
chr16:48639016(-) A-I      intronic
chr16:48579901(-) A-I      intronic
chr16:48639032(-) A-I      intronic
chr16:48627994(-) A-I      intronic
chr16:48579118(-) A-I      intronic
chr16:48638265(-) A-I      intronic
chr16:48579236(-) A-I      intronic
chr16:48629211(-) A-I      intronic
chr16:48641911(-) A-I      intronic
chr16:48639081(-) A-I      intronic
chr16:48579014(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED N4BP1
chr16:48638265(-) A-G intron -    22484847
chr16:48638407(-) A-G intron -    22484847
chr16:48639081(-) A-G intron -    22484847
chr16:48639082(-) A-G intron -    22484847
chr16:48642000(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase N4BP1
chr16:48576510-48576511(-) m6A 3'UTR       27773535
chr16:48576562-48576563(-) m6A 3'UTR       27773535
chr16:48576651-48576652(-) m6A 3'UTR       24981863//27773535
chr16:48576720-48576721(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr16:48576735-48576736(-) m6A 3'UTR       24209618//24981863//27773535//22608085
chr16:48576768-48576769(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//22608085
chr16:48576881-48576882(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr16:48576892-48576893(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr16:48576945-48576946(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr16:48576980-48576981(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr16:48580024-48580025(-) m6A exon//intron       27773535
chr16:48587502-48587503(-) m6A CDS//exon       27773535
chr16:48594699-48594700(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr16:48594720-48594721(-) m6A CDS//exon       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr16:48594810-48594811(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr16:48594960-48594961(-) m6A CDS//exon       24284625//24209618//24981863//26404942//27773535//22608085
chr16:48595088-48595089(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595096-48595097(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595114-48595115(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595120-48595121(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595140-48595141(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr16:48595146-48595147(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr16:48595160-48595161(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//22575960//22608085
chr16:48595197-48595198(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22575960//22608085
chr16:48595265-48595266(-) m6A CDS//exon       24284625//24209618//24981863//28052920//27773535//22608085
chr16:48595328-48595329(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr16:48595337-48595338(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr16:48595372-48595373(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr16:48595425-48595426(-) m6A CDS//exon       24284625//24981863//28052920//27773535//22608085
chr16:48595437-48595438(-) m6A CDS//exon       24284625//24981863//27773535//22608085
chr16:48595487-48595488(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr16:48595498-48595499(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22608085
chr16:48595532-48595533(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr16:48595610-48595611(-) m6A CDS//exon       24284625//24209618//24981863//27773535//27371828//22608085
chr16:48595798-48595799(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22608085
chr16:48595806-48595807(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22608085
chr16:48595829-48595830(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595865-48595866(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595916-48595917(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595958-48595959(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48595998-48595999(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48596047-48596048(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48596070-48596071(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48596116-48596117(-) m6A CDS//exon       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr16:48596212-48596213(-) m6A CDS//exon       24284625//24209618//24981863//28052920//26404942//27773535//27371828//22608085
chr16:48596296-48596297(-) m6A 5'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr16:48596325-48596326(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085
chr16:48596331-48596332(-) m6A 5'UTR//CDS//exon       24284625//24209618//24981863//27773535//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-654-3p
Exosome Plasma     23663360
Exosome Endothelial cells     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -
N4BP1
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID
Function Link  
RNAInter hsa-miR-654-3p
D-Glucose 5793 Drug interaction    RC00007238
Vorinostat 5311 Drug interaction    RC00007237
Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-654-3p

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-654-3p
Interactor2: N4BP1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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