Detail Information

Basic Information:


  VIRBase ID:  

HHID00025111

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-411-3p:           MX2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-411-3p MX2
miRBase
Accession/Entrez ID		 MIMAT0004813 4600
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MXB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-411-3p
rs1437940946 chr14:101023393    A/G
rs200209446 chr14:101023384    C/T
rs368977912 chr14:101023392    T/G
rs566979073 chr14:101023391    C/T
rs748033801 chr14:101023385    G/A
rs759656399 chr14:101023395    C/A
rs772106334 chr14:101023390    A/T
rs111835650 chr14:101023377    T/C
rs1285882332 chr14:101023382    C/A
rs1353902015 chr14:101023380    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MX2
chr21:42777078(+) A-I      intronic
chr21:42777026(+) A-I      intronic
chr21:42763388(+) A-I      intronic
chr21:42763435(+) A-I      intronic
chr21:42763436(+) A-I      intronic
chr21:42764798(+) A-I      intronic
chr21:42764822(+) A-I      intronic
chr21:42764856(+) A-I      intronic
chr21:42764870(+) A-I      intronic
chr21:42764886(+) A-I      intronic
chr21:42764912(+) A-I      intronic
chr21:42764913(+) A-I      intronic
chr21:42764918(+) A-I      intronic
chr21:42762670(+) A-I      intronic
chr21:42765012(+) A-I      intronic
chr21:42766621(+) A-I      intronic
chr21:42776981(+) A-I      intronic
chr21:42763337(+) A-I      intronic
chr21:42777011(+) A-I      intronic
chr21:42777127(+) A-I      intronic
chr21:42763382(+) A-I      intronic
chr21:42748437(+) A-I      intronic
chr21:42762754(+) A-I      intronic
chr21:42762878(+) A-I      intronic
chr21:42763449(+) A-I      intronic
chr21:42764878(+) A-I      intronic
chr21:42763378(+) A-I      intronic
chr21:42777020(+) A-I      intronic
chr21:42777883(+) A-I      intronic
chr21:42761405(+) A-I      intronic
chr21:42778158(+) A-I      intronic
chr21:42766614(+) A-I      intronic
chr21:42777090(+) A-I      intronic
chr21:42777169(+) A-I      intronic
chr21:42777841(+) A-I      intronic
chr21:42778177(+) A-I      intronic
chr21:42755128(+) A-I      intronic
chr21:42763529(+) A-I      intronic
chr21:42776958(+) A-I      intronic
chr21:42777996(+) A-I      intronic
chr21:42757987(+) A-I      intronic
chr21:42762818(+) A-I      intronic
chr21:42777812(+) A-I      intronic
chr21:42766747(+) A-I      intronic
chr21:42777060(+) A-I      intronic
chr21:42762786(+) A-I      intronic
chr21:42778150(+) A-I      intronic
chr21:42762812(+) A-I      intronic
chr21:42762769(+) A-I      intronic
chr21:42777021(+) A-I      intronic
chr21:42763350(+) A-I      intronic
chr21:42763439(+) A-I      intronic
chr21:42777203(+) A-I      intronic
chr21:42761435(+) A-I      intronic
chr21:42778149(+) A-I      intronic
chr21:42764981(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED MX2
chr21:42735274(+) A-G intron -    22484847
chr21:42762812(+) A-G intron -    22484847
chr21:42762818(+) A-G intron -    22484847
chr21:42763444(+) A-G intron -    22484847
chr21:42763449(+) A-G intron -    22484847
chr21:42763489(+) A-G intron -    22484847
chr21:42763492(+) A-G intron -    22484847
chr21:42777020(+) A-G intron -    22484847
chr21:42777059(+) A-G intron -    22484847
chr21:42777169(+) A-G intron -    22484847
chr21:42777170(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MX2
chr21:42738742-42738743(+) m6A exon//intron       -
chr21:42738835-42738836(+) m6A exon//intron       -
chr21:42738857-42738858(+) m6A exon//intron       -
chr21:42738908-42738909(+) m6A exon//intron       -
chr21:42738928-42738929(+) m6A exon//intron       -
chr21:42738947-42738948(+) m6A exon//intron       -
chr21:42738953-42738954(+) m6A exon//intron       -
chr21:42738961-42738962(+) m6A exon//intron       -
chr21:42738979-42738980(+) m6A exon//intron       -
chr21:42742141-42742142(+) m6A 5'UTR//intron       -
chr21:42742162-42742163(+) m6A 5'UTR//intron       -
chr21:42742228-42742229(+) m6A 5'UTR//intron       -
chr21:42742443-42742444(+) m6A 5'UTR//intron       -
chr21:42749017-42749018(+) m6A CDS       -
chr21:42749038-42749039(+) m6A CDS       -
chr21:42749059-42749060(+) m6A CDS       -
chr21:42749725-42749726(+) m6A CDS       -
chr21:42762564-42762565(+) m6A CDS//exon       -
chr21:42762606-42762607(+) m6A CDS//exon       -
chr21:42762618-42762619(+) m6A CDS//exon       -
chr21:42771144-42771145(+) m6A CDS//exon//intron       27773535
chr21:42771191-42771192(+) m6A CDS//exon//intron       27773535
chr21:42771228-42771229(+) m6A CDS//exon//intron       27773535
chr21:42771292-42771293(+) m6A exon//intron       27773535
chr21:42780064-42780065(+) m6A CDS//exon       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-411-3p
Exosome Plasma     23663360
Exosome B cell lymphoma cell lines|EBV-transformed lymphoblastoid B cells     25242326
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells|Urine     -
MX2
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-411-3p
Interactor2: MX2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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