Detail Information

Basic Information:


  VIRBase ID:  

HHID00025064

  Virus:  

Hantaan orthohantavirus (Hantaan virus 76-118)

  Host:  

Homo sapiens

  Confidence Score:  

0.6040

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-330-5p:           MOB3C:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-330-5p MOB3C
miRBase
Accession/Entrez ID		 MIMAT0004693 148932
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - MOB1E//MOBKL2C

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-330-5p
rs1349824380 chr19:45639070    A/G
rs1359949384 chr19:45639062    G/A
rs760888385 chr19:45639051    C/G
rs761051145 chr19:45639055    GAC/G
rs1450351295 chr19:45639066    A/T
rs562108564 chr19:45639069    G/T
rs768769902 chr19:45639068    A/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR MOB3C
chr1:47076167(-) A-I      intronic
chr1:47076153(-) A-I      intronic
chr1:47076152(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase MOB3C
chr1:47073615-47073616(-) m6A 3'UTR       -
chr1:47073653-47073654(-) m6A 3'UTR       -
chr1:47073801-47073802(-) m6A 3'UTR       24284625//24981863//27773535
chr1:47073813-47073814(-) m6A 3'UTR       24284625//24981863//27773535//27371828
chr1:47073882-47073883(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr1:47073925-47073926(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr1:47073953-47073954(-) m6A 3'UTR       25456834//24981863//27773535//27371828
chr1:47073999-47074000(-) m6A 3'UTR       24981863//27773535//27371828
chr1:47074059-47074060(-) m6A 3'UTR       27773535//27371828
chr1:47074071-47074072(-) m6A 3'UTR       27773535//27371828
chr1:47074087-47074088(-) m6A 3'UTR       27773535//27371828
chr1:47074147-47074148(-) m6A 3'UTR       24284625//24981863//27773535//27371828
chr1:47074256-47074257(-) m6A 3'UTR       24284625//24981863//27773535
chr1:47074310-47074311(-) m6A 3'UTR       24284625//24981863//27773535
chr1:47074323-47074324(-) m6A 3'UTR       24284625//24981863
chr1:47074385-47074386(-) m6A 3'UTR       24284625//24981863
chr1:47075096-47075097(-) m6A 3'UTR       27773535//27371828
chr1:47075117-47075118(-) m6A 3'UTR       27773535//27371828
chr1:47075197-47075198(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828
chr1:47075260-47075261(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr1:47075283-47075284(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr1:47075313-47075314(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr1:47075695-47075696(-) m6A CDS//exon       24284625//25456834//24981863//27371828//22608085
chr1:47075857-47075858(-) m6A CDS//exon       24284625//27773535
chr1:47078625-47078626(-) m6A CDS//exon       24284625//27371828
chr1:47078740-47078741(-) m6A CDS//exon       24209618//25456834//24981863//27371828//22575960
chr1:47078796-47078797(-) m6A CDS//exon       24209618//25456834//24981863//27371828//22575960
chr1:47078829-47078830(-) m6A CDS//exon       24284625//24209618//24981863//27371828//22575960
chr1:47078865-47078866(-) m6A CDS//exon       24284625//27371828
chr1:47078958-47078959(-) m6A CDS//exon       24284625//25456834//27371828//27773536
chr1:47079017-47079018(-) m6A 5'UTR//CDS//exon       24284625//25456834//27371828//27773536
chr1:47079175-47079176(-) m6A 5'UTR//intron       25456834//27371828
chr1:47079190-47079191(-) m6A 5'UTR//intron       25456834//24981863//27371828
chr1:47079224-47079225(-) m6A 5'UTR//intron       25456834//24981863
chr1:47079247-47079248(-) m6A 5'UTR//intron       25456834//24981863
chr1:47079265-47079266(-) m6A 5'UTR//intron       25456834//24981863
chr1:47079516-47079517(-) m6A 5'UTR//intron       25456834
chr1:47079573-47079574(-) m6A 5'UTR//intron       -
chr1:47080566-47080567(-) m6A 5'UTR//intron       -
chr1:47080622-47080623(-) m6A 5'UTR//intron       -
chr1:47080697-47080698(-) m6A 5'UTR//CDS//intron       -
chr1:47080717-47080718(-) m6A 5'UTR//CDS//intron       -
chr1:47080896-47080897(-) m6A 5'UTR//intron       -
chr1:47080948-47080949(-) m1A 5'UTR//intron       26863196
chr1:47080993-47080994(-) m6A 5'UTR//intron       27773535
chr1:47081117-47081118(-) m6A 5'UTR//intron       -
chr1:47082385-47082386(-) m6A 5'UTR//exon       24209618//25456834//24981863
chr1:47082442-47082443(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828
chr1:47082456-47082457(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828
chr1:47082476-47082477(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828
chr1:47082488-47082489(-) m6A 5'UTR//exon       24209618//25456834//24981863//27371828

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-330-5p
Exosome HCC tissues     30542726
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
MOB3C
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-330-5p
D-Glucose 5793 Drug interaction    RC00007082
Mistletoe lectin-I - Drug interaction    RC00007083
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-330-5p
Etoposide 36462       23028896

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-330-5p
Interactor2: MOB3C

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB//miRTarBase//miRWalk//Targetscan
Support Database ViRBase

References:


PMID 32232013 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line HUVEC cells Interactor2 expression Upregulation
Description Then we predicted 320 target genes of these 16 DE miRNAs and constructed a miRNA-mRNA interaction network (Figure 5B, Table S5).

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