Basic Information:

  VIRBase ID:  

HHID00023527

  Virus:  

Zika virus (strain SZ01,ZIKV)

  Host:  

Mus musculus

  Confidence Score:  

0.7311

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-9-5p:  MIMAT0000142          Rest:  NM_011263     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-9-5p	Rest
miRBase Accession/Entrez ID	MIMAT0000142	19712
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	2610008J04Rik//AA407358//D14Mgi1//N//NRSF//REST4

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Rest	chr5:77265545-77265546(+) m6A 5'UTR       25683224//25412662//25569111 chr5:77265578-77265579(+) m6A 5'UTR       25683224//25412662//24981863//25569111 chr5:77265593-77265594(+) m6A 5'UTR       25683224//25412662//24981863//25569111 chr5:77265610-77265611(+) m6A 5'UTR       25683224//25412662//24981863//25569111 chr5:77265765-77265766(+) m6A 5'UTR       25683224//25412662//24981863//25456834//25569111 chr5:77266233-77266234(+) m6A 5'UTR//intron       25683224//25412662//24981863//25456834//25569111 chr5:77266289-77266290(+) m6A 5'UTR//intron       25683224//25412662//25569111 chr5:77268059-77268060(+) m6A CDS       25683224//25412662//24981863//25569111 chr5:77268181-77268182(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268247-77268248(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268254-77268255(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268284-77268285(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268354-77268355(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268370-77268371(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77268506-77268507(+) m6A CDS       25683224//25412662//25569111 chr5:77268719-77268720(+) m6A CDS       25683224//25569111 chr5:77268730-77268731(+) m6A CDS       25683224//25569111 chr5:77268781-77268782(+) m6A CDS       25683224//25569111 chr5:77268813-77268814(+) m6A CDS       25683224//25569111 chr5:77275255-77275256(+) m6A CDS       25683224//25569111 chr5:77275283-77275284(+) m6A CDS       25683224//25569111 chr5:77275307-77275308(+) m6A CDS       25683224//25569111 chr5:77280775-77280776(+) m6A CDS       25683224//24981863//25569111 chr5:77280796-77280797(+) m6A CDS       25683224//24981863//25569111 chr5:77280827-77280828(+) m6A CDS       24981863//25569111 chr5:77280974-77280975(+) m6A CDS       25683224//25456834//24981863//25569111 chr5:77281007-77281008(+) m6A CDS       25683224//25456834//24981863//25412662//25569111 chr5:77281073-77281074(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281079-77281080(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281103-77281104(+) m1A CDS       26863196 chr5:77281114-77281115(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281154-77281155(+) m1A CDS       26863196 chr5:77281196-77281197(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281223-77281224(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281243-77281244(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77281255-77281256(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281266-77281267(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281299-77281300(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281354-77281355(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281502-77281503(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281508-77281509(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281528-77281529(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281553-77281554(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281558-77281559(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281599-77281600(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281646-77281647(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77281759-77281760(+) m6A CDS       25683224//25456834//24981863//25412662//25569111 chr5:77281894-77281895(+) m6A CDS       25683224//25412662//24981863//25569111 chr5:77281924-77281925(+) m6A CDS       25683224//25412662//24981863//25569111 chr5:77282136-77282137(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77282223-77282224(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282244-77282245(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282259-77282260(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282295-77282296(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282309-77282310(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282319-77282320(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085 chr5:77282348-77282349(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282377-77282378(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282449-77282450(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282454-77282455(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282498-77282499(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282526-77282527(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282540-77282541(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282562-77282563(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282604-77282605(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282755-77282756(+) m6A CDS       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr5:77282893-77282894(+) m6A CDS       25683224//25456834//25412662//24981863//25569111 chr5:77283011-77283012(+) m6A 3'UTR       25683224//25456834//25412662//24981863//25569111 chr5:77283041-77283042(+) m6A 3'UTR       25683224//25456834//24981863//25412662//25569111 chr5:77283106-77283107(+) m6A 3'UTR       25683224//24981863//25569111 chr5:77283171-77283172(+) m6A 3'UTR       25683224//24981863//25569111 chr5:77283227-77283228(+) m6A 3'UTR       25683224//25569111 chr5:77283437-77283438(+) m6A 3'UTR       - chr5:77284164-77284165(+) m6A 3'UTR       25683224 chr5:77284181-77284182(+) m6A 3'UTR       25683224 chr5:77284188-77284189(+) m6A 3'UTR       25683224 chr5:77284302-77284303(+) m6A 3'UTR       25683224 chr5:77284725-77284726(+) m6A 3'UTR       25683224 chr5:77284775-77284776(+) m6A 3'UTR       25683224 chr5:77284820-77284821(+) m6A 3'UTR       25683224 chr5:77284872-77284873(+) m6A 3'UTR       25683224 chr5:77285123-77285124(+) m6A 3'UTR       25683224 chr5:77285129-77285130(+) m6A 3'UTR       25683224 chr5:77285146-77285147(+) m6A 3'UTR       25683224 chr5:77285170-77285171(+) m6A 3'UTR       25683224 chr5:77285195-77285196(+) m6A 3'UTR       25683224 chr5:77285220-77285221(+) m6A 3'UTR       25683224 chr5:77285226-77285227(+) m6A 3'UTR       25683224 chr5:77285319-77285320(+) m6A 3'UTR       25683224 chr5:77285328-77285329(+) m6A 3'UTR       25683224 chr5:77285354-77285355(+) m6A 3'UTR       25683224 chr5:77285580-77285581(+) m6A 3'UTR       25569111 chr5:77285696-77285697(+) m6A 3'UTR       25569111 chr5:77285717-77285718(+) m6A 3'UTR       25569111 chr5:77285818-77285819(+) m6A 3'UTR       25683224//25569111 chr5:77285867-77285868(+) m6A 3'UTR       25683224//25569111 chr5:77285917-77285918(+) m6A 3'UTR       25683224//24981863//25569111 chr5:77286012-77286013(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr5:77286082-77286083(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr5:77286092-77286093(+) m6A 3'UTR       25683224//25456834//24981863//25569111 chr5:77286137-77286138(+) m6A 3'UTR       25569111 chr5:77286175-77286176(+) m6A 3'UTR       25569111

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-9-5p	Axon Motor neurons     30233312 Cell body Motor neurons     30233312 Exosome Serum     28160157 Exosome B6 BMDCs     22031862 Exosome Mouse hypothalamic neuronal cell line (GT1-7)     22965126
	Rest	Nucleus Neuroblastoma cell line (N2A)     22406755

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-9-5p
Interactor2: Rest

Evidence Support:

Strong-Evidence	RT-PCR
Support Database	ViRBase

References:

PMID	30264295	Target region	None
Source	ViRBase	Interactor1 expression	Upregulation
Tissue or cell line	Mouse Brain	Interactor2 expression	None
Description	Furthermore, to test whether other known miR-9 target genes also were affected by miR-9 upregulation due to ZIKV infection, we examined expression levels of Bcl2l11, Rest, Hes1, Hdac5, and Foxp2 using real-time RT-PCR. Except Hdac5, expression levels of Bcl2l11, Rest, Hes1, and Foxp2 were decreased (Fig. S5A-E).