Basic Information:

  VIRBase ID:  

HHID00023452

  Virus:  

Zika virus (strain RIO-U1,ZIKV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6775

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26b-3p:  MIMAT0004500          NCAM2:  NM_001352592     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-26b-3p	NCAM2
miRBase Accession/Entrez ID	MIMAT0004500	4685
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	NCAM21

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-26b-3p	rs373131632 chr2:218402710    G/A rs752111841 chr2:218402711    C/G rs752111841 chr2:218402711    C/T rs752183955 chr2:218402700    C/G rs757962316 chr2:218402701    C/T rs912863478 chr2:218402692    C/A rs912863478 chr2:218402692    C/T rs1233068699 chr2:218402699    T/G rs1354053050 chr2:218402695    GTT/G

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	NCAM2	chr21:22861418(+) A-I      intronic chr21:22546418(+) A-I      intronic chr21:22546341(+) A-I      intronic chr21:22803157(+) A-I      intronic chr21:22861412(+) A-I      intronic chr21:22546421(+) A-I      intronic chr21:22803158(+) A-I      intronic chr21:22585201(+) A-I      intronic chr21:22546367(+) A-I      intronic chr21:22566000(+) A-I      intronic chr21:22823171(+) A-I      intronic chr21:22546342(+) A-I      intronic chr21:22861416(+) A-I      intronic chr21:22811340(+) A-I      intronic chr21:22811148(+) A-I      intronic chr21:22811139(+) A-I      intronic chr21:22803113(+) A-I      intronic chr21:22803112(+) A-I      intronic chr21:22782435(+) A-I      intronic chr21:22782270(+) A-I      intronic chr21:22782265(+) A-I      intronic chr21:22782256(+) A-I      intronic chr21:22683826(+) A-I      intronic chr21:22683802(+) A-I      intronic chr21:22683800(+) A-I      intronic chr21:22588012(+) A-I      intronic chr21:22547689(+) A-I      intronic chr21:22547674(+) A-I      intronic chr21:22547606(+) A-I      intronic chr21:22514777(+) A-I      intronic chr21:22509997(+) A-I      intronic chr21:22509980(+) A-I      intronic chr21:22509978(+) A-I      intronic chr21:22509850(+) A-I      intronic chr21:22509841(+) A-I      intronic chr21:22508909(+) A-I      intronic chr21:22508897(+) A-I      intronic chr21:22508879(+) A-I      intronic chr21:22496366(+) A-I      intronic chr21:22496331(+) A-I      intronic chr21:22496327(+) A-I      intronic chr21:22495601(+) A-I      intronic chr21:22495466(+) A-I      intronic chr21:22493100(+) A-I      intronic chr21:22452772(+) A-I      intronic chr21:22424583(+) A-I      intronic chr21:22420853(+) A-I      intronic chr21:22420811(+) A-I      intronic chr21:22397578(+) A-I      intronic chr21:22397532(+) A-I      intronic chr21:22397161(+) A-I      intronic chr21:22397149(+) A-I      intronic chr21:22397061(+) A-I      intronic chr21:22396938(+) A-I      intronic chr21:22389695(+) A-I      intronic chr21:22389472(+) A-I      intronic chr21:22896801(+) A-I      intronic chr21:22896821(+) A-I      intronic chr21:22763404(+) A-I      intronic chr21:22858570(+) A-I      intronic chr21:22858537(+) A-I      intronic chr21:22858478(+) A-I      intronic chr21:22452769(+) A-I      intronic chr21:22858465(+) A-I      intronic chr21:22858369(+) A-I      intronic chr21:22812728(+) A-I      intronic chr21:22811377(+) A-I      intronic chr21:22811347(+) A-I      intronic chr21:22851758(+) A-I      intronic chr21:22729096(+) A-I      intronic chr21:22507221(+) A-I      intronic chr21:22506579(+) A-I      intronic chr21:22587943(+) A-I      intronic chr21:22509399(+) A-I      intronic chr21:22389556(+) A-I      intronic chr21:22416007(+) A-I      intronic chr21:22452830(+) A-I      intronic chr21:22564487(+) A-I      intronic chr21:22724184(+) A-I      intronic chr21:22797245(+) A-I      intronic chr21:22416052(+) A-I      intronic chr21:22453964(+) A-I      intronic chr21:22415983(+) A-I      intronic chr21:22400364(+) A-I      intronic chr21:22591106(+) A-I      intronic chr21:22455768(+) A-I      intronic chr21:22398698(+) A-I      intronic chr21:22547603(+) A-I      intronic chr21:22399412(+) A-I      intronic chr21:22724451(+) A-I      intronic chr21:22723316(+) A-I      intronic chr21:22444491(+) A-I      intronic chr21:22444437(+) A-I      intronic chr21:22723322(+) A-I      intronic chr21:22728151(+) A-I      intronic chr21:22727595(+) A-I      intronic chr21:22395688(+) A-I      intronic chr21:22414547(+) A-I      intronic chr21:22388125(+) A-I      intronic chr21:22724200(+) A-I      intronic chr21:22811711(+) A-I      intronic chr21:22386088(+) A-I      intronic chr21:22386620(+) A-I      intronic chr21:22630029(+) A-I      intronic chr21:22389541(+) A-I      intronic chr21:22420878(+) A-I      intronic chr21:22728030(+) A-I      intronic chr21:22727604(+) A-I      intronic chr21:22397542(+) A-I      intronic chr21:22630092(+) A-I      intronic chr21:22727707(+) A-I      intronic chr21:22388101(+) A-I      intronic chr21:22453854(+) A-I      intronic chr21:22397676(+) A-I      intronic chr21:22546428(+) A-I      intronic chr21:22763431(+) A-I      intronic chr21:22388206(+) A-I      intronic chr21:22509345(+) A-I      intronic chr21:22861525(+) A-I      intronic chr21:22437426(+) A-I      intronic chr21:22452883(+) A-I      intronic chr21:22507375(+) A-I      intronic chr21:22724206(+) A-I      intronic chr21:22546515(+) A-I      intronic chr21:22851784(+) A-I      intronic chr21:22630175(+) A-I      intronic chr21:22454291(+) A-I      intronic chr21:22409405(+) A-I      intronic chr21:22587949(+) A-I      intronic chr21:22797235(+) A-I      intronic chr21:22420856(+) A-I      intronic chr21:22455922(+) A-I      intronic chr21:22416062(+) A-I      intronic chr21:22727491(+) A-I      intronic chr21:22452679(+) A-I      intronic chr21:22416008(+) A-I      intronic chr21:22400255(+) A-I      intronic chr21:22452705(+) A-I      intronic chr21:22688912(+) A-I      intronic chr21:22398721(+) A-I      intronic chr21:22397129(+) A-I      intronic chr21:22395694(+) A-I      intronic chr21:22503648(+) A-I      intronic chr21:22547598(+) A-I      intronic chr21:22507485(+) A-I      intronic chr21:22388150(+) A-I      intronic chr21:22495502(+) A-I      intronic chr21:22630032(+) A-I      intronic chr21:22587836(+) A-I      intronic chr21:22727605(+) A-I      intronic chr21:22861356(+) A-I      intronic chr21:22389485(+) A-I      intronic chr21:22546493(+) A-I      intronic chr21:22507060(+) A-I      intronic chr21:22454384(+) A-I      intronic chr21:22727634(+) A-I      intronic chr21:22454424(+) A-I      intronic chr21:22546371(+) A-I      intronic chr21:22503731(+) A-I      intronic chr21:22803287(+) A-I      intronic chr21:22400275(+) A-I      intronic chr21:22547740(+) A-I      intronic chr21:22629966(+) A-I      intronic chr21:22588022(+) A-I      intronic chr21:22723290(+) A-I      intronic chr21:22386010(+) A-I      intronic chr21:22896783(+) A-I      intronic chr21:22452748(+) A-I      intronic chr21:22415968(+) A-I      intronic chr21:22385978(+) A-I      intronic chr21:22724532(+) A-I      intronic chr21:22699542(+) A-I      intronic chr21:22591162(+) A-I      intronic chr21:22585266(+) A-I      intronic chr21:22388288(+) A-I      intronic chr21:22389566(+) A-I      intronic chr21:22388263(+) A-I      intronic chr21:22507453(+) A-I      intronic chr21:22388299(+) A-I      intronic chr21:22725313(+) A-I      intronic chr21:22397159(+) A-I      intronic chr21:22398795(+) A-I      intronic chr21:22861474(+) A-I      intronic chr21:22452813(+) A-I      intronic chr21:22386637(+) A-I      intronic chr21:22630020(+) A-I      intronic chr21:22385921(+) A-I      intronic chr21:22727711(+) A-I      intronic chr21:22861516(+) A-I      intronic chr21:22547675(+) A-I      intronic chr21:22861579(+) A-I      intronic chr21:22547597(+) A-I      intronic chr21:22487278(+) A-I      intronic chr21:22507298(+) A-I      intronic chr21:22397007(+) A-I      intronic chr21:22861422(+) A-I      intronic chr21:22630086(+) A-I      intronic chr21:22416026(+) A-I      intronic chr21:22547695(+) A-I      intronic chr21:22509868(+) A-I      intronic chr21:22416013(+) A-I      intronic chr21:22630100(+) A-I      intronic chr21:22506516(+) A-I      intronic chr21:22503721(+) A-I      intronic chr21:22385987(+) A-I      intronic chr21:22435722(+) A-I      intronic chr21:22861590(+) A-I      intronic chr21:22397006(+) A-I      intronic chr21:22509054(+) A-I      intronic chr21:22630068(+) A-I      intronic chr21:22385977(+) A-I      intronic chr21:22851650(+) A-I      intronic chr21:22455802(+) A-I      intronic chr21:22516616(+) A-I      intronic chr21:22797236(+) A-I      intronic chr21:22728037(+) A-I      intronic chr21:22388121(+) A-I      intronic chr21:22507144(+) A-I      intronic chr21:22861381(+) A-I      intronic chr21:22725251(+) A-I      intronic chr21:22507080(+) A-I      intronic chr21:22547700(+) A-I      intronic chr21:22399411(+) A-I      intronic chr21:22389658(+) A-I      intronic chr21:22542012(+) A-I      intronic chr21:22388287(+) A-I      intronic chr21:22400386(+) A-I      intronic chr21:22507514(+) A-I      intronic chr21:22398761(+) A-I      intronic chr21:22585179(+) A-I      intronic chr21:22495438(+) A-I      intronic chr21:22630048(+) A-I      intronic chr21:22507621(+) A-I      intronic chr21:22444397(+) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	NCAM2	chr21:22452813(+) A-I intron -    15342557 chr21:22453889(+) A-I intron -    15342557 chr21:22453964(+) A-I intron -    15342557 chr21:22629966(+) A-I intron -    15342557 chr21:22630020(+) A-I intron -    15342557 chr21:22630029(+) A-I intron -    15342557 chr21:22630032(+) A-I intron -    15342557 chr21:22630048(+) A-I intron -    15342557 chr21:22630068(+) A-I intron -    15342557 chr21:22630086(+) A-I intron -    15342557 chr21:22630092(+) A-I intron -    15342557 chr21:22630100(+) A-I intron -    15342557 chr21:22630113(+) A-I intron -    15342557 chr21:22454291(+) A-G intron -    22484847 chr21:22516616(+) A-G intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	NCAM2	chr21:22881349-22881350(+) m6A CDS       27773535 chr21:22906875-22906876(+) m6A CDS       27773535 chr21:22906894-22906895(+) m6A CDS       27773535 chr21:22906954-22906955(+) m6A CDS       27773535 chr21:22906971-22906972(+) m6A CDS       27773535 chr21:22910300-22910301(+) m6A 3'UTR       - chr21:22910345-22910346(+) m6A 3'UTR       - chr21:22910375-22910376(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-26b-3p	Exosome Breast milk     22211110 Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Follicular fluid     23666971 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
	NCAM2	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus K562 cells     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-26b-3p
Interactor2: NCAM2

Evidence Support:

Weak-Evidence	RNA-Seq//Small RNA sequencing
Prediction-Evidence	DIANA//miRanda//PicTar//Targetscan
Support Database	ViRBase

References:

PMID	31992777	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	TEC cells	Interactor2 expression	None
Description	The microRNA-target network (Fig. 4b,c) revealed 13 upregulated microRNAs that can modulate the expression of 12 downregulated target transcripts.