Detail Information

Basic Information:


  VIRBase ID:  

HHID00023451

  Virus:  

Zika virus (strain RIO-U1,ZIKV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6775

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-26b-3p:           KLRC2:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-26b-3p KLRC2
miRBase
Accession/Entrez ID		 MIMAT0004500 3822
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CD159c//NKG2-C//NKG2C

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-26b-3p
rs373131632 chr2:218402710    G/A
rs752111841 chr2:218402711    C/G
rs752111841 chr2:218402711    C/T
rs752183955 chr2:218402700    C/G
rs757962316 chr2:218402701    C/T
rs912863478 chr2:218402692    C/A
rs912863478 chr2:218402692    C/T
rs1233068699 chr2:218402699    T/G
rs1354053050 chr2:218402695    GTT/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR KLRC2
chr12:10591470(-) A-I      intronic
chr12:10591492(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KLRC2
chr12:10588480-10588481(-) m6A CDS//intron       24981863//27773535
chr12:10588485-10588486(-) m6A CDS//intron       24981863//27773535
chr12:10588516-10588517(-) m6A CDS//intron       24981863//27773535
chr12:10588538-10588539(-) m6A CDS//intron       24981863//27773535
chr12:10588566-10588567(-) m6A CDS//intron       24981863
chr12:10588576-10588577(-) m6A CDS//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-26b-3p
Exosome Breast milk     22211110
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Follicular fluid     23666971
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
KLRC2
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-26b-3p
Interactor2: KLRC2

Evidence Support:


Weak-Evidence RNA-Seq//Small RNA sequencing
Prediction-Evidence DIANA//miRanda//PicTar//Targetscan
Support Database ViRBase

References:


PMID 31992777 Target region None
Source ViRBase Interactor1 expression Downregulation
Tissue or cell line TEC cells Interactor2 expression None
Description The microRNA-target network (Fig. 4b,c) revealed 13 upregulated microRNAs that can modulate the expression of 12 downregulated target transcripts.

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