Basic Information:

  VIRBase ID:  

HHID00020474

  Virus:  

Japanese encephalitis virus (P3 strain)

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-122-5p:  MIMAT0000246          Pik3ap1:  NM_031376     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-122-5p	Pik3ap1
miRBase Accession/Entrez ID	MIMAT0000246	83490
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	1810044J04Rik//BC//BCAP

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Pik3ap1	chr19:41274255-41274256(-) m6A 3'UTR       25683224//24981863 chr19:41274264-41274265(-) m6A 3'UTR       25683224//24981863 chr19:41281905-41281906(-) m6A CDS       25683224//24981863 chr19:41281916-41281917(-) m6A CDS       25683224//24981863 chr19:41281928-41281929(-) m6A CDS       25683224//24981863 chr19:41287489-41287490(-) m6A CDS       25683224//24981863 chr19:41287501-41287502(-) m6A CDS       25683224//24981863 chr19:41287520-41287521(-) m6A CDS       25683224//24981863 chr19:41292810-41292811(-) m6A CDS       25683224//24981863 chr19:41375881-41375882(-) m6A CDS       24981863 chr19:41375946-41375947(-) m6A CDS       24981863 chr19:41376029-41376030(-) m6A CDS       24981863 chr19:41376108-41376109(-) m6A CDS       24981863 chr19:41376148-41376149(-) m6A CDS       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-122-5p	Cytoplasm Hepatocytes     29253196 Exosome Serum     28160157 Exosome B6 BMDCs     22031862 Mitochondrion Liver tissue     27396686 Mitochondrion Liver cells     27563705 Mitochondrion Liver tissue     20733615 Nucleus Hepatic carcinoma cells (Hepa1-6)|Hepatocytes     29253196 Nucleus Liver cells     21862971

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-122-5p
Interactor2: Pik3ap1

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32552669	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	Mice brain tissues	Interactor2 expression	None
Description	The circRNA-miRNA-mRNA ceRNA network.In total, we detected 569 negatively regulated miRNA-circRNA pairs and 2719 negatively regulated miRNA-mRNA pairs (Additional file 6: Table S5).