Basic Information:

  VIRBase ID:  

HHID00019805

  Virus:  

Japanese encephalitis virus (P3 strain)

  Host:  

Mus musculus

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      mmu-miR-124-3p:  MIMAT0000134          Cflar:  NR_149257     

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Interactor Information:

	Interactor1	Interactor2
Symbol	mmu-miR-124-3p	Cflar
miRBase Accession/Entrez ID	MIMAT0000134	12633
Organism	Mus musculus	Mus musculus
Category	miRNA	mRNA
Alias	-	2310024N18Rik//A430105C05Rik//c-F//c-Flip//Ca//Cash//Casper//CLARP//F//FLAME//FLAME-1//Flip//Gm9845//I-FLICE//MRIT

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	Cflar	chr1:58713459-58713460(+) m6A 5'UTR//exon//intron       24981863//25569111 chr1:58722483-58722484(+) m6A exon//intron       24981863 chr1:58722502-58722503(+) m6A exon//intron       24981863 chr1:58722561-58722562(+) m6A exon//intron       24981863 chr1:58722567-58722568(+) m6A exon//intron       24981863 chr1:58722605-58722606(+) m6A exon//intron       24981863 chr1:58722626-58722627(+) m6A exon//intron       24981863 chr1:58722654-58722655(+) m6A exon//intron       24981863 chr1:58723039-58723040(+) m6A exon//intron       24981863 chr1:58726402-58726403(+) m6A 5'UTR//exon       24981863 chr1:58726413-58726414(+) m6A 5'UTR//exon       24981863 chr1:58726434-58726435(+) m6A 5'UTR//exon       24981863 chr1:58726542-58726543(+) m6A CDS//exon       24981863 chr1:58726566-58726567(+) m6A CDS//exon       24981863 chr1:58731236-58731237(+) m6A CDS//exon       24981863 chr1:58731251-58731252(+) m6A CDS//exon       24981863 chr1:58731257-58731258(+) m6A CDS//exon       24981863 chr1:58752352-58752353(+) m6A CDS//exon       24981863 chr1:58752455-58752456(+) m6A CDS//exon       24981863//25569111//22608085 chr1:58752557-58752558(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr1:58752572-58752573(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr1:58752620-58752621(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr1:58752692-58752693(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr1:58752714-58752715(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085//22575960 chr1:58753800-58753801(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085 chr1:58753813-58753814(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085 chr1:58753821-58753822(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085 chr1:58753839-58753840(+) m6A CDS//exon       25683224//25456834//25412662//24981863//25569111//22608085 chr1:58753900-58753901(+) m6A CDS//exon       25456834//25412662//24981863//25569111//22608085 chr1:58753924-58753925(+) m6A 3'UTR//exon       25412662//24981863//25569111//22608085 chr1:58753931-58753932(+) m6A 3'UTR//exon       25412662//24981863//25569111//22608085 chr1:58754675-58754676(+) m6A 3'UTR       25412662 chr1:58754723-58754724(+) m6A 3'UTR       25412662 chr1:58755164-58755165(+) m6A 3'UTR       24981863 chr1:58755594-58755595(+) m6A 3'UTR       25412662 chr1:58755645-58755646(+) m6A 3'UTR       25412662 chr1:58755650-58755651(+) m6A 3'UTR       25412662 chr1:58755655-58755656(+) m6A 3'UTR       25412662 chr1:58755689-58755690(+) m6A 3'UTR       25412662 chr1:58755694-58755695(+) m6A 3'UTR       25412662 chr1:58756706-58756707(+) m6A 3'UTR       24981863 chr1:58756871-58756872(+) m6A 3'UTR       24981863 chr1:58756901-58756902(+) m6A 3'UTR       25412662//24981863 chr1:58756911-58756912(+) m6A 3'UTR       25412662//24981863 chr1:58756930-58756931(+) m6A 3'UTR       25412662//24981863 chr1:58757007-58757008(+) m6A 3'UTR       25412662//24981863//22608085 chr1:58758267-58758268(+) m6A 3'UTR       25683224//25412662//24981863 chr1:58758373-58758374(+) m6A 3'UTR       25683224//25412662 chr1:58758400-58758401(+) m6A 3'UTR       25683224//25412662

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	mmu-miR-124-3p	Axon Motor neurons     30233312 Cell body Motor neurons     30233312 Cell body Neuron ball cultures     23897634 Dendrite Hippocampal neurons     24784359 Exosome Serum     28160157 Exosome BV2 microglial cells     31190315 Exosome Mouse hypothalamic neuronal cell line (GT1-7)     22965126 Exosome Spinal motor neuron     32712030 Postsynaptic density ForeBrain     18410515 Synaptoneurosome ForeBrain     18410515

Interaction Network (The top 100 interactions):

Interactor1: mmu-miR-124-3p
Interactor2: Cflar

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	miRanda
Support Database	ViRBase

References:

PMID	32552669	Target region	None
Source	ViRBase	Interactor1 expression	Downregulation
Tissue or cell line	Mice brain tissues	Interactor2 expression	None
Description	The circRNA-miRNA-mRNA ceRNA network.In total, we detected 569 negatively regulated miRNA-circRNA pairs and 2719 negatively regulated miRNA-mRNA pairs (Additional file 6: Table S5).