Basic Information:

  VIRBase ID:  

HHID00019564

  Virus:  

Hepacivirus C (Hepatitis C virus subtype 2a,HCV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-501-3p:  MIMAT0004774          RNF144A:  NR_146069     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-501-3p	RNF144A
miRBase Accession/Entrez ID	MIMAT0004774	9781
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	hUIP4//RNF144//UBCE7IP4

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-501-3p	rs112489955 chrX:50009781    G/A rs112489955 chrX:50009781    G/T rs1557182212 chrX:50009793    T/C rs376696825 chrX:50009787    G/A rs376696825 chrX:50009787    G/T rs781947379 chrX:50009780    C/T rs782814071 chrX:50009784    C/T rs149912461 chrX:50009773    A/G rs1557182197 chrX:50009774    T/C rs367629841 chrX:50009778    C/T rs782056456 chrX:50009775    G/A

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	RNF144A	chr2:7062787(+) A-I      intronic chr2:7110098(+) A-I      intronic chr2:7165651(+) A-I      intronic chr2:7110032(+) A-I      intronic chr2:7115807(+) A-I      intronic chr2:7115699(+) A-I      intronic chr2:7070996(+) A-I      intronic chr2:7183052(+) A-I      3'UTR chr2:7062940(+) A-I      intronic chr2:7110022(+) A-I      intronic chr2:7115846(+) A-I      intronic chr2:7165585(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	RNF144A	chr2:7180186-7180187(+) m6A 3'UTR//intron       24981863 chr2:7180215-7180216(+) m6A 3'UTR//intron       24981863 chr2:7180271-7180272(+) m6A 3'UTR//intron       24981863 chr2:7180288-7180289(+) m6A 3'UTR//intron       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-501-3p	Exosome Primary dendritic cells     21505438 Exosome Plasma     23663360 Exosome Human mast cell line (HMC-1)     24009880 Exosome Blood     - Microvesicle Seminal plasma     23539611 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     - Mitochondrion Myotube     27396686 Mitochondrion Skeletal muscle cells     27563705 Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	RNF144A	Chromatin K562 cells     - Exosome Blood     - Membrane HCC cell line (HepG2)     - Nucleolus K562 cells     - Nucleoplasm K562 cells     - Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:

Resource	Symbol	Drug Name	PubChem ID	PMID
NoncoRNA	hsa-miR-501-3p	Cisplatin 5702198       30221699

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-501-3p
Interactor2: RNF144A

Evidence Support:

Weak-Evidence	Microarray
Prediction-Evidence	DIANA//miRDB//Targetscan
Support Database	ViRBase

References:

PMID	31076402	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	Huh7.5.1 cells	Interactor2 expression	None
Description	Table 1. Computational analysis of miR-501-3p and miR-619-3p targets and pathway enrichment.