Detail Information

Basic Information:


  VIRBase ID:  

HHID00019503

  Virus:  

Hepacivirus C (Hepatitis C virus subtype 1b,HCV)

  Host:  

Homo sapiens

  Confidence Score:  

0.1828

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-215-3p:           SIRT4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-215-3p SIRT4
miRBase
Accession/Entrez ID		 MIMAT0026476 23409
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - SIR2L4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-215-3p
rs1333471638 chr1:220117882    G/A
rs749489380 chr1:220117883    C/G
rs754286532 chr1:220117889    GA/G
rs1345487830 chr1:220117895    A/G
rs757646667 chr1:220117893    TGACA/T
rs768393822 chr1:220117898    G/A

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SIRT4
chr12:120749933(+) A-I      intronic
chr12:120749932(+) A-I      intronic
chr12:120749924(+) A-I      intronic
chr12:120749921(+) A-I      intronic
chr12:120743273(+) A-I      intronic
chr12:120749939(+) A-I      intronic
chr12:120749463(+) A-I      intronic
chr12:120741217(+) A-I      intronic
chr12:120742243(+) A-I      intronic
chr12:120742267(+) A-I      intronic
chr12:120742277(+) A-I      intronic
chr12:120742850(+) A-I      intronic
chr12:120743238(+) A-I      intronic
chr12:120743261(+) A-I      intronic
chr12:120742842(+) A-I      intronic
chr12:120745036(+) A-I      intronic
chr12:120745171(+) A-I      intronic
chr12:120748412(+) A-I      intronic
chr12:120742863(+) A-I      intronic
chr12:120749450(+) A-I      intronic
chr12:120742333(+) A-I      intronic
chr12:120743085(+) A-I      intronic
chr12:120743077(+) A-I      intronic
chr12:120743193(+) A-I      intronic
chr12:120742413(+) A-I      intronic
chr12:120744204(+) A-I      intronic
chr12:120747496(+) A-I      intronic
chr12:120744469(+) A-I      intronic
chr12:120742558(+) A-I      intronic
chr12:120742291(+) A-I      intronic
chr12:120747868(+) A-I      intronic
chr12:120749488(+) A-I      intronic
chr12:120745408(+) A-I      intronic
chr12:120745169(+) A-I      intronic
chr12:120743326(+) A-I      intronic
chr12:120743285(+) A-I      intronic
chr12:120747709(+) A-I      intronic
chr12:120742198(+) A-I      intronic
chr12:120748488(+) A-I      intronic
chr12:120747648(+) A-I      intronic
chr12:120741121(+) A-I      intronic
chr12:120742837(+) A-I      intronic
chr12:120749904(+) A-I      intronic
chr12:120744158(+) A-I      intronic
chr12:120743561(+) A-I      intronic
chr12:120743948(+) A-I      intronic
chr12:120747703(+) A-I      intronic
chr12:120742877(+) A-I      intronic
chr12:120742498(+) A-I      intronic
chr12:120742795(+) A-I      intronic
chr12:120741157(+) A-I      intronic
chr12:120746163(+) A-I      intronic
chr12:120746851(+) A-I      intronic
chr12:120743932(+) A-I      intronic
chr12:120742836(+) A-I      intronic
chr12:120741005(+) A-I      intronic
chr12:120747619(+) A-I      intronic
chr12:120747478(+) A-I      intronic
chr12:120742750(+) A-I      intronic
chr12:120748937(+) A-I      intronic
chr12:120744024(+) A-I      intronic
chr12:120746138(+) A-I      intronic
chr12:120742528(+) A-I      intronic
chr12:120741011(+) A-I      intronic
chr12:120748418(+) A-I      intronic
chr12:120748282(+) A-I      intronic
chr12:120742293(+) A-I      intronic
chr12:120743179(+) A-I      intronic
chr12:120746968(+) A-I      intronic
chr12:120747705(+) A-I      intronic
chr12:120744023(+) A-I      intronic
chr12:120746237(+) A-I      intronic
chr12:120743123(+) A-I      intronic
chr12:120746786(+) A-I      intronic
chr12:120747658(+) A-I      intronic
chr12:120745934(+) A-I      intronic
chr12:120742338(+) A-I      intronic
chr12:120742571(+) A-I      intronic
chr12:120749404(+) A-I      intronic
chr12:120743264(+) A-I      intronic
chr12:120749418(+) A-I      intronic
chr12:120743929(+) A-I      intronic
chr12:120743128(+) A-I      intronic
chr12:120742756(+) A-I      intronic
chr12:120747572(+) A-I      intronic
chr12:120746238(+) A-I      intronic
chr12:120744456(+) A-I      intronic
chr12:120744485(+) A-I      intronic
chr12:120742878(+) A-I      intronic
chr12:120748210(+) A-I      intronic
chr12:120747398(+) A-I      intronic
chr12:120747794(+) A-I      intronic
chr12:120749273(+) A-I      intronic
chr12:120746259(+) A-I      intronic
chr12:120748121(+) A-I      intronic
chr12:120745177(+) A-I      intronic
chr12:120748440(+) A-I      intronic
chr12:120745407(+) A-I      intronic
chr12:120742806(+) A-I      intronic
chr12:120743255(+) A-I      intronic
chr12:120742551(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SIRT4
chr12:120746870(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SIRT4
chr12:120741419-120741420(+) m6A 5'UTR//CDS       24284625//24981863//22608085
chr12:120741482-120741483(+) m6A 5'UTR//CDS       24284625//25456834//24981863//22608085
chr12:120741531-120741532(+) m6A 5'UTR//CDS       24284625//25456834//24981863//22608085
chr12:120741581-120741582(+) m6A CDS       24284625//25456834//24981863//22608085
chr12:120741689-120741690(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr12:120741762-120741763(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr12:120741857-120741858(+) m6A CDS//exon       24284625//25456834//24981863//22608085
chr12:120750282-120750283(+) m6A CDS//intron       24284625//25456834//24981863//22608085
chr12:120750326-120750327(+) m6A CDS//intron       24284625//25456834//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-215-3p
Exosome HCC cell line (Hep3B|HepG2|PLC/PRF/5)     21721029
Exosome Ovarian follicular fluid     22116803
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells     -
SIRT4
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-215-3p
Interactor2: SIRT4

Evidence Support:


Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 29749134 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line None Interactor2 expression None
Description Therefore, the miRNA target prediction tool Targetscan was used to search for the potential targets of miR-215.

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