Detail Information

Basic Information:


  VIRBase ID:  

HHID00019434

  Virus:  

Hepacivirus C (Hepatitis C virus JFH-1,HCV)

  Host:  

Homo sapiens

  Confidence Score:  

0.7802

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-130a-5p:           CD80:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-130a-5p CD80
miRBase
Accession/Entrez ID		 MIMAT0004593 941
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - B7//B7-1//B7.1//BB1//CD28LG//CD28LG1//LAB7

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-130a-5p
rs746985078 chr11:57641223    A/G
rs779670380 chr11:57641222    C/T
rs758215186 chr11:57641219    T/G

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR CD80
chr3:119250622(-) A-I      intronic
chr3:119256562(-) A-I      intronic
chr3:119256481(-) A-I      intronic
chr3:119256461(-) A-I      intronic
chr3:119256423(-) A-I      intronic
chr3:119255474(-) A-I      intronic
chr3:119255428(-) A-I      intronic
chr3:119255359(-) A-I      intronic
chr3:119259691(-) A-I      intronic
chr3:119259645(-) A-I      intronic
chr3:119259030(-) A-I      intronic
chr3:119259001(-) A-I      intronic
chr3:119258991(-) A-I      intronic
chr3:119267034(-) A-I      intronic
chr3:119267870(-) A-I      intronic
chr3:119250632(-) A-I      intronic
chr3:119248024(-) A-I      intronic
chr3:119247998(-) A-I      intronic
chr3:119247953(-) A-I      intronic
chr3:119247918(-) A-I      intronic
chr3:119247912(-) A-I      intronic
chr3:119267693(-) A-I      intronic
chr3:119267056(-) A-I      intronic
chr3:119267004(-) A-I      intronic
chr3:119250648(-) A-I      intronic
chr3:119263007(-) A-I      intronic
chr3:119262934(-) A-I      intronic
chr3:119262928(-) A-I      intronic
chr3:119262480(-) A-I      intronic
chr3:119262464(-) A-I      intronic
chr3:119262463(-) A-I      intronic
chr3:119262457(-) A-I      intronic
chr3:119259857(-) A-I      intronic
chr3:119259786(-) A-I      intronic
chr3:119267725(-) A-I      intronic
chr3:119267776(-) A-I      intronic
chr3:119259678(-) A-I      intronic
chr3:119258976(-) A-I      intronic
chr3:119258964(-) A-I      intronic
chr3:119258961(-) A-I      intronic
chr3:119258932(-) A-I      intronic
chr3:119255309(-) A-I      intronic
chr3:119255060(-) A-I      intronic
chr3:119255011(-) A-I      intronic
chr3:119251183(-) A-I      intronic
chr3:119251144(-) A-I      intronic
chr3:119250778(-) A-I      intronic
chr3:119250738(-) A-I      intronic
chr3:119256580(-) A-I      intronic
chr3:119247911(-) A-I      intronic
chr3:119255052(-) A-I      intronic
chr3:119267005(-) A-I      intronic
chr3:119259864(-) A-I      intronic
chr3:119262908(-) A-I      intronic
chr3:119253822(-) A-I      intronic
chr3:119254949(-) A-I      intronic
chr3:119259730(-) A-I      intronic
chr3:119255458(-) A-I      intronic
chr3:119259881(-) A-I      intronic
chr3:119259693(-) A-I      intronic
chr3:119255015(-) A-I      intronic
chr3:119255457(-) A-I      intronic
chr3:119251095(-) A-I      intronic
chr3:119256605(-) A-I      intronic
chr3:119259692(-) A-I      intronic
chr3:119262842(-) A-I      intronic
chr3:119259773(-) A-I      intronic
chr3:119255012(-) A-I      intronic
chr3:119262409(-) A-I      intronic
chr3:119271147(-) A-I      intronic
chr3:119272183(-) A-I      intronic
chr3:119259746(-) A-I      intronic
chr3:119262954(-) A-I      intronic
chr3:119258938(-) A-I      intronic
chr3:119250784(-) A-I      intronic
chr3:119255303(-) A-I      intronic
chr3:119255476(-) A-I      intronic
chr3:119259723(-) A-I      intronic
chr3:119247925(-) A-I      intronic
chr3:119267716(-) A-I      intronic
chr3:119254998(-) A-I      intronic
chr3:119259813(-) A-I      intronic
chr3:119254854(-) A-I      intronic
chr3:119256446(-) A-I      intronic
chr3:119266992(-) A-I      intronic
chr3:119247549(-) A-I      intronic
chr3:119264109(-) A-I      intronic
chr3:119267108(-) A-I      intronic
chr3:119255290(-) A-I      intronic
chr3:119255356(-) A-I      intronic
chr3:119254864(-) A-I      intronic
chr3:119251253(-) A-I      intronic
chr3:119277470(-) A-I      intronic
chr3:119254950(-) A-I      intronic
chr3:119255404(-) A-I      intronic
chr3:119251092(-) A-I      intronic
chr3:119255051(-) A-I      intronic
chr3:119262986(-) A-I      intronic
chr3:119262953(-) A-I      intronic
chr3:119259812(-) A-I      intronic
chr3:119247725(-) A-I      intronic
chr3:119267801(-) A-I      intronic
chr3:119255422(-) A-I      intronic
chr3:119262905(-) A-I      intronic
chr3:119248000(-) A-I      intronic
chr3:119271227(-) A-I      intronic
chr3:119256432(-) A-I      intronic
chr3:119255250(-) A-I      intronic
chr3:119247603(-) A-I      intronic
chr3:119255452(-) A-I      intronic
chr3:119256567(-) A-I      intronic
chr3:119259747(-) A-I      intronic
chr3:119247683(-) A-I      intronic
chr3:119255242(-) A-I      intronic
chr3:119267007(-) A-I      intronic
chr3:119255434(-) A-I      intronic
chr3:119247589(-) A-I      intronic
chr3:119259728(-) A-I      intronic
chr3:119259724(-) A-I      intronic
chr3:119262899(-) A-I      intronic
chr3:119266924(-) A-I      intronic
chr3:119250748(-) A-I      intronic
chr3:119255065(-) A-I      intronic
chr3:119255401(-) A-I      intronic
chr3:119247935(-) A-I      intronic
chr3:119267010(-) A-I      intronic
chr3:119251090(-) A-I      intronic
chr3:119263026(-) A-I      intronic
chr3:119256483(-) A-I      intronic
chr3:119263002(-) A-I      intronic
chr3:119247921(-) A-I      intronic
chr3:119277981(-) A-I      intronic
chr3:119259733(-) A-I      intronic
chr3:119262841(-) A-I      intronic
chr3:119251157(-) A-I      intronic
chr3:119256566(-) A-I      intronic
chr3:119250712(-) A-I      intronic
chr3:119264108(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED CD80
chr3:119250783(-) A-I intron -    22327324
chr3:119250784(-) A-I intron -    22327324
chr3:119251092(-) A-I intron -    22327324
chr3:119255434(-) A-I intron -    22327324
chr3:119247486(-) A-G intron -    22484847
chr3:119247589(-) A-G intron -    22484847
chr3:119247603(-) A-G intron -    22484847
chr3:119247606(-) A-G intron -    22484847
chr3:119247651(-) A-G intron -    22484847
chr3:119247911(-) A-G intron -    22484847
chr3:119247921(-) A-G intron -    22484847
chr3:119247925(-) A-G intron -    22484847
chr3:119247935(-) A-G intron -    22484847
chr3:119247979(-) A-G intron -    22484847
chr3:119248000(-) A-G intron -    22484847
chr3:119250690(-) G-A intron -    22484847
chr3:119250704(-) A-G intron -    22484847
chr3:119250712(-) A-G intron -    22484847
chr3:119250783(-) A-G intron -    22484847
chr3:119250784(-) A-G intron -    22484847
chr3:119251092(-) A-G intron -    22484847
chr3:119251095(-) A-G intron -    22484847
chr3:119251098(-) A-G intron -    22484847
chr3:119251104(-) A-G intron -    22484847
chr3:119251157(-) A-G intron -    22484847
chr3:119251253(-) A-G intron -    22484847
chr3:119251257(-) A-G intron -    22484847
chr3:119251282(-) T-C intron -    22484847
chr3:119251345(-) C-T intron -    22484847
chr3:119253822(-) A-G intron -    22484847
chr3:119253849(-) T-C intron -    22484847
chr3:119254842(-) A-G intron -    22484847
chr3:119254854(-) A-G intron -    22484847
chr3:119254864(-) A-G intron -    22484847
chr3:119254869(-) G-A intron -    22484847
chr3:119254949(-) A-G intron -    22484847
chr3:119254950(-) A-G intron -    22484847
chr3:119254998(-) A-G intron -    22484847
chr3:119255012(-) A-G intron -    22484847
chr3:119255015(-) A-G intron -    22484847
chr3:119255051(-) A-G intron -    22484847
chr3:119255052(-) A-G intron -    22484847
chr3:119255065(-) A-G intron -    22484847
chr3:119255242(-) A-G intron -    22484847
chr3:119255356(-) A-G intron -    22484847
chr3:119255357(-) A-G intron -    22484847
chr3:119255369(-) A-G intron -    22484847
chr3:119255404(-) A-G intron -    22484847
chr3:119255422(-) A-G intron -    22484847
chr3:119255434(-) A-G intron -    22484847
chr3:119255452(-) A-G intron -    22484847
chr3:119255457(-) A-G intron -    22484847
chr3:119255458(-) A-G intron -    22484847
chr3:119255476(-) A-G intron -    22484847
chr3:119256432(-) A-G intron -    22484847
chr3:119256446(-) A-G intron -    22484847
chr3:119256483(-) A-G intron -    22484847
chr3:119256496(-) A-G intron -    22484847
chr3:119256566(-) A-G intron -    22484847
chr3:119256567(-) A-G intron -    22484847
chr3:119256602(-) A-G intron -    22484847
chr3:119256605(-) A-G intron -    22484847
chr3:119258875(-) A-G intron -    22484847
chr3:119258938(-) A-G intron -    22484847
chr3:119258997(-) A-G intron -    22484847
chr3:119259068(-) A-G intron -    22484847
chr3:119259069(-) A-G intron -    22484847
chr3:119259639(-) A-G intron -    22484847
chr3:119259684(-) A-G intron -    22484847
chr3:119259692(-) A-G intron -    22484847
chr3:119259693(-) A-G intron -    22484847
chr3:119259713(-) A-G intron -    22484847
chr3:119259723(-) A-G intron -    22484847
chr3:119259724(-) A-G intron -    22484847
chr3:119259728(-) A-G intron -    22484847
chr3:119259730(-) A-G intron -    22484847
chr3:119259733(-) A-G intron -    22484847
chr3:119259746(-) A-G intron -    22484847
chr3:119259747(-) A-G intron -    22484847
chr3:119259773(-) A-G intron -    22484847
chr3:119259787(-) A-G intron -    22484847
chr3:119259795(-) A-G intron -    22484847
chr3:119259812(-) A-G intron -    22484847
chr3:119259813(-) A-G intron -    22484847
chr3:119259833(-) A-G intron -    22484847
chr3:119259864(-) A-G intron -    22484847
chr3:119259873(-) A-G intron -    22484847
chr3:119259881(-) A-G intron -    22484847
chr3:119262460(-) A-G intron -    22484847
chr3:119262841(-) A-G intron -    22484847
chr3:119262842(-) A-G intron -    22484847
chr3:119262872(-) A-G intron -    22484847
chr3:119262899(-) A-G intron -    22484847
chr3:119262953(-) A-G intron -    22484847
chr3:119262954(-) A-G intron -    22484847
chr3:119262986(-) A-G intron -    22484847
chr3:119263002(-) A-G intron -    22484847
chr3:119263026(-) A-G intron -    22484847
chr3:119264108(-) A-G intron -    22484847
chr3:119264109(-) A-G intron -    22484847
chr3:119266901(-) A-G intron -    22484847
chr3:119266992(-) A-G intron -    22484847
chr3:119267005(-) A-G intron -    22484847
chr3:119267006(-) A-G intron -    22484847
chr3:119267007(-) A-G intron -    22484847
chr3:119267010(-) A-G intron -    22484847
chr3:119267021(-) A-G intron -    22484847
chr3:119267108(-) A-G intron -    22484847
chr3:119267801(-) A-G intron -    22484847
chr3:119272183(-) A-G intron -    22484847
chr3:119277470(-) A-G intron -    22484847
chr3:119277524(-) A-G intron -    22484847
chr3:119277532(-) A-G intron -    22484847
chr3:119277629(-) T-A intron -    22484847
chr3:119277981(-) A-G intron -    22484847

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-130a-5p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
CD80
Cytosol K562 cells     -
Exosome Blood     -
Membrane K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-130a-5p
Eloxatine 5310940 Drug interaction    RC00006934
5-Fluorouracil 3385 Drug interaction    RC00006933
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-130a-5p
Tamoxifen 2733526       30840279

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-130a-5p
Interactor2: CD80

Evidence Support:


Strong-Evidence qRT-PCR
Prediction-Evidence miRanda
Support Database ViRBase

References:


PMID 30974864 Target region 3'UTR
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line Huh7.5.1 cells Interactor2 expression None
Description The four downregulated genes following miR-130a overexpression were confirmed by qPCR: (A) ATG5; (B) CASP1; (C) CD80; and (D) IL18.

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