Detail Information

Basic Information:


  VIRBase ID:  

HHID00019204

  Virus:  

Hepacivirus C (Hepatitis C virus genotype 2,HCV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8935

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30d-5p:           PIP4K2B:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30d-5p PIP4K2B
miRBase
Accession/Entrez ID		 MIMAT0000245 8396
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PI5P4KB//PIP5K2B//PIP5KIIB//PIP5KIIbeta//PIP5P4KB

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30d-5p
rs1203910650 chr8:134804928    G/A
rs1244539439 chr8:134804930    G/T
rs1441595222 chr8:134804927    C/A
rs1441595222 chr8:134804927    C/T
rs374432132 chr8:134804931    G/A
rs776972352 chr8:134804925    G/A
rs1187386485 chr8:134804934    G/A
rs1373057893 chr8:134804937    TACA/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIP4K2B
chr17:36943471(-) A-I      intronic
chr17:36943517(-) A-I      intronic
chr17:36933370(-) A-I      intronic
chr17:36951921(-) A-I      intronic
chr17:36933355(-) A-I      intronic
chr17:36943458(-) A-I      intronic
chr17:36943462(-) A-I      intronic
chr17:36949881(-) A-I      intronic
chr17:36933348(-) A-I      intronic
chr17:36933347(-) A-I      intronic
chr17:36928171(-) A-I      intronic
chr17:36933378(-) A-I      intronic
chr17:36944102(-) A-I      intronic
chr17:36928937(-) A-I      intronic
chr17:36928932(-) A-I      intronic
chr17:36940026(-) A-I      intronic
chr17:36941681(-) A-I      intronic
chr17:36941747(-) A-I      intronic
chr17:36943341(-) A-I      intronic
chr17:36943545(-) A-I      intronic
chr17:36944097(-) A-I      intronic
chr17:36947803(-) A-I      intronic
chr17:36944575(-) A-I      intronic
chr17:36944582(-) A-I      intronic
chr17:36944586(-) A-I      intronic
chr17:36944656(-) A-I      intronic
chr17:36928139(-) A-I      intronic
chr17:36945084(-) A-I      intronic
chr17:36945119(-) A-I      intronic
chr17:36928127(-) A-I      intronic
chr17:36928064(-) A-I      intronic
chr17:36931669(-) A-I      intronic
chr17:36945253(-) A-I      intronic
chr17:36950015(-) A-I      intronic
chr17:36948590(-) A-I      intronic
chr17:36948624(-) A-I      intronic
chr17:36949716(-) A-I      intronic
chr17:36949734(-) A-I      intronic
chr17:36950092(-) A-I      intronic
chr17:36949748(-) A-I      intronic
chr17:36950075(-) A-I      intronic
chr17:36943958(-) A-I      intronic
chr17:36945285(-) A-I      intronic
chr17:36946674(-) A-I      intronic
chr17:36946991(-) A-I      intronic
chr17:36946999(-) A-I      intronic
chr17:36947768(-) A-I      intronic
chr17:36947787(-) A-I      intronic
chr17:36947800(-) A-I      intronic
chr17:36947801(-) A-I      intronic
chr17:36950079(-) A-I      intronic
chr17:36947856(-) A-I      intronic
chr17:36947895(-) A-I      intronic
chr17:36947926(-) A-I      intronic
chr17:36948225(-) A-I      intronic
chr17:36948237(-) A-I      intronic
chr17:36948286(-) A-I      intronic
chr17:36948323(-) A-I      intronic
chr17:36948548(-) A-I      intronic
chr17:36932380(-) A-I      intronic
chr17:36932420(-) A-I      intronic
chr17:36932770(-) A-I      intronic
chr17:36933425(-) A-I      intronic
chr17:36933514(-) A-I      intronic
chr17:36937830(-) A-I      intronic
chr17:36937862(-) A-I      intronic
chr17:36938059(-) A-I      intronic
chr17:36939250(-) A-I      intronic
chr17:36939329(-) A-I      intronic
chr17:36939336(-) A-I      intronic
chr17:36939348(-) A-I      intronic
chr17:36939391(-) A-I      intronic
chr17:36939916(-) A-I      intronic
chr17:36944726(-) A-I      intronic
chr17:36939919(-) A-I      intronic
chr17:36932352(-) A-I      intronic
chr17:36932104(-) A-I      intronic
chr17:36931791(-) A-I      intronic
chr17:36931629(-) A-I      intronic
chr17:36930899(-) A-I      intronic
chr17:36928967(-) A-I      intronic
chr17:36945366(-) A-I      intronic
chr17:36928079(-) A-I      intronic
chr17:36945286(-) A-I      intronic
chr17:36939259(-) A-I      intronic
chr17:36946849(-) A-I      intronic
chr17:36952345(-) A-I      intronic
chr17:36932796(-) A-I      intronic
chr17:36931759(-) A-I      intronic
chr17:36948175(-) A-I      intronic
chr17:36941677(-) A-I      intronic
chr17:36931773(-) A-I      intronic
chr17:36932362(-) A-I      intronic
chr17:36943968(-) A-I      intronic
chr17:36939273(-) A-I      intronic
chr17:36928242(-) A-I      intronic
chr17:36946742(-) A-I      intronic
chr17:36949634(-) A-I      intronic
chr17:36943324(-) A-I      intronic
chr17:36945277(-) A-I      intronic
chr17:36949764(-) A-I      intronic
chr17:36952002(-) A-I      intronic
chr17:36945344(-) A-I      intronic
chr17:36945309(-) A-I      intronic
chr17:36949234(-) A-I      intronic
chr17:36931479(-) A-I      intronic
chr17:36932361(-) A-I      intronic
chr17:36933526(-) A-I      intronic
chr17:36946989(-) A-I      intronic
chr17:36948227(-) A-I      intronic
chr17:36948305(-) A-I      intronic
chr17:36944853(-) A-I      intronic
chr17:36939888(-) A-I      intronic
chr17:36945250(-) A-I      intronic
chr17:36929012(-) A-I      intronic
chr17:36937898(-) A-I      intronic
chr17:36950081(-) A-I      intronic
chr17:36949873(-) A-I      intronic
chr17:36929006(-) A-I      intronic
chr17:36951841(-) A-I      intronic
chr17:36933414(-) A-I      intronic
chr17:36949907(-) A-I      intronic
chr17:36932028(-) A-I      intronic
chr17:36939276(-) A-I      intronic
chr17:36947759(-) A-I      intronic
chr17:36944637(-) A-I      intronic
chr17:36933590(-) A-I      intronic
chr17:36944565(-) A-I      intronic
chr17:36945122(-) A-I      intronic
chr17:36928038(-) A-I      intronic
chr17:36938056(-) A-I      intronic
chr17:36949319(-) A-I      intronic
chr17:36949956(-) A-I      intronic
chr17:36944862(-) A-I      intronic
chr17:36931699(-) A-I      intronic
chr17:36939853(-) A-I      intronic
chr17:36948302(-) A-I      intronic
chr17:36939921(-) A-I      intronic
chr17:36949867(-) A-I      intronic
chr17:36929113(-) A-I      intronic
chr17:36950042(-) A-I      intronic
chr17:36928221(-) A-I      intronic
chr17:36949994(-) A-I      intronic
chr17:36949880(-) A-I      intronic
chr17:36947866(-) A-I      intronic
chr17:36946996(-) A-I      intronic
chr17:36939324(-) A-I      intronic
chr17:36929129(-) A-I      intronic
chr17:36944847(-) A-I      intronic
chr17:36948462(-) A-I      intronic
chr17:36950078(-) A-I      intronic
chr17:36937908(-) A-I      intronic
chr17:36932495(-) A-I      intronic
chr17:36950056(-) A-I      intronic
chr17:36931478(-) A-I      intronic
chr17:36944865(-) A-I      intronic
chr17:36945260(-) A-I      intronic
chr17:36943417(-) A-I      intronic
chr17:36945019(-) A-I      intronic
chr17:36944717(-) A-I      intronic
chr17:36946695(-) A-I      intronic
chr17:36928128(-) A-I      intronic
chr17:36928077(-) A-I      intronic
chr17:36938206(-) A-I      intronic
chr17:36947935(-) A-I      intronic
chr17:36931683(-) A-I      intronic
chr17:36939196(-) A-I      intronic
chr17:36951882(-) A-I      intronic
chr17:36929070(-) A-I      intronic
chr17:36928244(-) A-I      intronic
chr17:36943538(-) A-I      intronic
chr17:36947698(-) A-I      intronic
chr17:36948313(-) A-I      intronic
chr17:36938190(-) A-I      intronic
chr17:36944866(-) A-I      intronic
chr17:36928078(-) A-I      intronic
chr17:36948086(-) A-I      intronic
chr17:36948564(-) A-I      intronic
chr17:36943459(-) A-I      intronic
chr17:36932880(-) A-I      intronic
chr17:36950093(-) A-I      intronic
chr17:36938049(-) A-I      intronic
chr17:36939184(-) A-I      intronic
chr17:36949305(-) A-I      intronic
chr17:36943984(-) A-I      intronic
chr17:36950002(-) A-I      intronic
chr17:36932822(-) A-I      intronic
chr17:36943944(-) A-I      intronic
chr17:36928999(-) A-I      intronic
chr17:36937803(-) A-I      intronic
chr17:36945256(-) A-I      intronic
chr17:36946749(-) A-I      intronic
chr17:36950067(-) A-I      intronic
chr17:36944592(-) A-I      intronic
chr17:36948454(-) A-I      intronic
chr17:36945324(-) A-I      intronic
chr17:36949673(-) A-I      intronic
chr17:36928269(-) A-I      intronic
chr17:36943509(-) A-I      intronic
chr17:36949565(-) A-I      intronic
chr17:36952226(-) A-I      intronic
chr17:36949635(-) A-I      intronic
chr17:36949306(-) A-I      intronic
chr17:36945124(-) A-I      intronic
chr17:36932816(-) A-I      intronic
chr17:36933517(-) A-I      intronic
chr17:36951941(-) A-I      intronic
chr17:36928167(-) A-I      intronic
chr17:36933584(-) A-I      intronic
chr17:36933455(-) A-I      intronic
chr17:36949879(-) A-I      intronic
chr17:36948540(-) A-I      intronic
chr17:36940762(-) A-I      intronic
chr17:36945094(-) A-I      intronic
chr17:36952269(-) A-I      intronic
chr17:36944249(-) A-I      intronic
chr17:36928931(-) A-I      intronic
chr17:36950012(-) A-I      intronic
chr17:36949757(-) A-I      intronic
chr17:36949906(-) A-I      intronic
chr17:36947934(-) A-I      intronic
chr17:36940688(-) A-I      intronic
chr17:36944117(-) A-I      intronic
chr17:36949249(-) A-I      intronic
chr17:36948474(-) A-I      intronic
chr17:36938120(-) A-I      intronic
chr17:36933279(-) A-I      intronic
chr17:36929034(-) A-I      intronic
chr17:36949967(-) A-I      intronic
chr17:36937747(-) A-I      intronic
chr17:36948098(-) A-I      intronic
chr17:36940720(-) A-I      intronic
chr17:36946683(-) A-I      intronic
chr17:36931501(-) A-I      intronic
chr17:36945697(-) A-I      intronic
chr17:36928231(-) A-I      intronic
chr17:36945367(-) A-I      intronic
chr17:36950024(-) A-I      intronic
chr17:36941680(-) A-I      intronic
chr17:36943421(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PIP4K2B
chr17:36928079(-) A-G intron -    22484847
chr17:36929006(-) A-G intron -    22484847
chr17:36932317(-) C-T intron -    22484847
chr17:36932495(-) A-G intron -    22484847
chr17:36943421(-) A-G intron -    22484847
chr17:36946996(-) A-G intron -    22484847
chr17:36948462(-) A-G intron -    22484847
chr17:36950012(-) A-G intron -    22484847
chr17:36950024(-) A-G intron -    22484847
chr17:36950081(-) A-G intron -    22484847
chr17:36950093(-) A-G intron -    22484847
chr17:36952345(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIP4K2B
chr17:36924027-36924028(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924071-36924072(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924092-36924093(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924099-36924100(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924119-36924120(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924133-36924134(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924175-36924176(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924204-36924205(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924235-36924236(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr17:36924302-36924303(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924332-36924333(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924375-36924376(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924398-36924399(-) Am 3'UTR       -
chr17:36924415-36924416(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924444-36924445(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924508-36924509(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr17:36924541-36924542(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:36924638-36924639(-) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr17:36924860-36924861(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr17:36924911-36924912(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr17:36924997-36924998(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr17:36925006-36925007(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr17:36925042-36925043(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//27371828//22575960//22608085
chr17:36925068-36925069(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27371828//22575960//22608085
chr17:36925161-36925162(-) m6A 3'UTR       24284625//24209618//24981863//27371828//22575960//22608085
chr17:36925179-36925180(-) m6A 3'UTR       24284625//24209618//24981863//27371828//22575960//22608085
chr17:36925318-36925319(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27371828//22608085
chr17:36925418-36925419(-) m6A 3'UTR       24284625//24209618//24981863//22608085
chr17:36925453-36925454(-) m6A 3'UTR       24284625//24209618//24981863//22608085
chr17:36925477-36925478(-) m6A 3'UTR       24284625//24209618//24981863
chr17:36925785-36925786(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr17:36925810-36925811(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960
chr17:36925998-36925999(-) m6A CDS       24209618//24981863//27773535//27371828
chr17:36926694-36926695(-) m6A CDS       24209618//24981863//27773535
chr17:36927358-36927359(-) m6A CDS       27371828
chr17:36927466-36927467(-) m6A CDS//exon       24209618//25456834//24981863//27773535//27371828
chr17:36927499-36927500(-) m6A CDS//exon       24209618//25456834//24981863//27773535//27371828
chr17:36933957-36933958(-) m6A CDS//exon       24209618//24981863//27773535//27371828//22575960
chr17:36933970-36933971(-) m6A CDS//exon       24209618//24981863//27773535//27371828//22575960
chr17:36934027-36934028(-) m6A CDS//exon       24981863//27773535//27371828
chr17:36934045-36934046(-) m6A CDS//exon       24981863//27773535//27371828
chr17:36935703-36935704(-) m6A CDS//exon       27773535
chr17:36955525-36955526(-) m6A CDS//exon//intron       24209618
chr17:36955601-36955602(-) m1A CDS//exon//intron       26863410//26863196
chr17:36955610-36955611(-) m6A CDS//exon//intron       24284625//24209618//27371828
chr17:36955616-36955617(-) m6A CDS//exon//intron       24284625//24209618//27371828
chr17:36955831-36955832(-) m6A 5'UTR//intron       24981863
chr17:36955926-36955927(-) m6A 5'UTR//intron       27371828//27773536
chr17:36956140-36956141(-) m6A 5'UTR//intron       25456834//24981863//27371828//27773536
chr17:36956284-36956285(-) m6A 5'UTR       25456834//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30d-5p
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Exosome HCC tissues     30542726
Exosome Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Renal cancer cells     21670082
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Cerebrospinal fluid     25420022
Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Colon tissue|Endothelial cells|Epithelial cells|Kidney tissue|Lymphoma tissue|Mast cells|Seminal fluid|Tongue tissue     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Hepatocellular carcinoma cell line (HepG2)|Lung epithelial carcinoma cell line (A549)     20615901
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
PIP4K2B
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)     -

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-30d-5p
Midostaurin 9829523 Drug resistant
Herveline O 5459269 Drug sensitive
Cuspidatin C 5459164 Drug sensitive
2,7-Bis(methoxycarbonylmethyl)-10-methylphenothiazine 384444 Drug sensitive
2-Acetyl-1,2-dihydroellipticine 376328 Drug resistant
Antimycin A3 245869 Drug sensitive
5-Hydroxy-3-phenylpyrano[3,2-c]chromen-2(5H)-one 24205741 Drug sensitive
4,5-Bis(4-methoxyphenyl)-1,5-dihydroimidazol-2-one 231112 Drug sensitive
Kinetin riboside 20345 Drug resistant
Astrazon Orange R 135747272 Drug sensitive
Cladospirone bisepoxide 10316810 Drug sensitive
(3Z,4R)-4-Hydroxy-3-[2-[(1S,3R)-3-[2-[(1S,3S,3'R,4S)-1-hydroxy-4,6,6-trimethylspiro[2,5-dioxabicyclo[2.2.2]octane-3,6'-oxane]-3'-yl]ethyl]-2,2-dimethyl-6-methylidenecyclohexyl]ethylidene]oxolan-2-one 101206903 Drug sensitive
antineoplastic-d655481 - Drug resistant
4-[4-(3-Methoxy-phenyl)-piperazin-1 -yl]-5H-pyrrolo[3,2-d]pyrimidine - Drug sensitive
4-morpholinecarbodithioic acid, antimony complex - Drug sensitive
7-n,n-dimethylamino brefeldin a hydrochloride - Drug sensitive
E)-1-(4-(quinazolin-4-ylamino)phenyl)-3-(2,4,6-trimethoxyphenyl)prop-2-en-1-one - Drug sensitive
isatin dr - Drug sensitive
tetra(isobutenyl)antimony bromide - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30d-5p
Gemcitabine 60750 Drug interaction    RC00001621
Sunitinib 5329102 Drug interaction    RC00001626
Eloxatine 5310940 Drug interaction    RC00001625
Trichostatin A 444732 Drug interaction    RC00001624
Paroxetine 43815 Drug interaction    RC00001620
Etoposide 36462 Drug interaction    RC00001619
5-Fluorouracil 3385 Drug interaction    RC00001617
Doxorubicin 31703 Drug interaction    RC00001618
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00001616
Verapamil 2520 Drug interaction    RC00001615
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719 Drug interaction    RC00001627
Bicalutamide 2375 Drug interaction    RC00001614
Docetaxel 148124 Drug interaction    RC00001623
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00001628
Trastuzumab - Drug interaction    RC00001629
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30d-5p
N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide 24180719       26456124

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30d-5p
Interactor2: PIP4K2B

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence miRNA array
Prediction-Evidence miRanda//PicTar//RNAHybrid//Targetscan
Support Database VIRmiRNA

References:


PMID 23418453 Target region 3'UTR
Source VIRmiRNA Interactor1 expression None
Tissue or cell line Huh7.5 cells Interactor2 expression None
Description Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-alpha treatment (p<0.01). The miR-30(a-d) cluster and miR-130a/301 and their putative mRNA targets were predicted to be associated with cellular pathways that involve Hepatitis C virus entry, propagation and host response to viral infection.

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