Detail Information

Basic Information:


  VIRBase ID:  

HHID00019094

  Virus:  

Hepacivirus C (Hepatitis C virus genotype 2,HCV)

  Host:  

Homo sapiens

  Confidence Score:  

0.8935

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-30a-5p:           CFL2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-30a-5p CFL2
miRBase
Accession/Entrez ID		 MIMAT0000087 1073
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - NEM7

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-30a-5p
rs1328441296 chr6:71403607    G/A
rs1464132840 chr6:71403605    AG/A
rs190842689 chr6:71403603    C/A
rs190842689 chr6:71403603    C/G
rs190842689 chr6:71403603    C/T
rs745794419 chr6:71403595    C/T
rs762257046 chr6:71403602    TCGAGGA/T
rs764130578 chr6:71403596    T/TGTAC
rs768265589 chr6:71403604    G/A
rs768265589 chr6:71403604    G/C
rs772062415 chr6:71403598    C/T
rs774439748 chr6:71403601    G/GC
rs934018633 chr6:71403600    A/C
rs767944817 chr6:71403611    TTTACA/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CFL2
chr14:35179597-35179598(-) m6A 3'UTR       27773535
chr14:35179614-35179615(-) m6A 3'UTR       27773535
chr14:35181516-35181517(-) Y 3'UTR       26075521
chr14:35181827-35181828(-) m6A 3'UTR       26404942
chr14:35181863-35181864(-) m6A 3'UTR       26404942
chr14:35181892-35181893(-) m6A 3'UTR       26404942
chr14:35182079-35182080(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182118-35182119(-) Gm 3'UTR//CDS       -
chr14:35182137-35182138(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182175-35182176(-) m6A 3'UTR//CDS       24981863//26404942
chr14:35182477-35182478(-) m6A CDS//intron       27773535
chr14:35182499-35182500(-) m6A CDS//intron       27773535
chr14:35182573-35182574(-) m6A CDS//intron       24981863//26404942//27773535//22608085
chr14:35182635-35182636(-) m6A CDS//intron       24981863//27773535//22608085
chr14:35182942-35182943(-) m6A 5'UTR//intron       24981863//22608085
chr14:35182979-35182980(-) m6A 5'UTR//intron       24981863
chr14:35183934-35183935(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-30a-5p
Cytoplasm Cell line (HeLa)     21695135
Cytoplasm Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Cytoplasmic stress granule HeLa cells     28488892
Exosome Primary dendritic cells     21505438
Exosome Renal cancer cells     21670082
Exosome Brain tissue     23382797
Exosome Plasma     23663360
Exosome Human mast cell line (HMC-1)     24009880
Exosome Cerebrospinal fluid     25420022
Exosome Blood|B lymphoblastoid cells|Breast milk|Chronic lymphocytic leukemia cells|Endothelial cells|Epithelial cells|Kidney tissue|Mast cells|Seminal fluid|Tongue tissue     -
Extracellular vesicle HEK-293T cells     22849433
Microvesicle Plasma     23077538
Microvesicle Seminal plasma     23539611
Microvesicle Follicular fluid     23666971
Microvesicle Hepatoma cells     23771658
Microvesicle Blood|Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
Nucleolus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
Nucleus Breast adenocarcinoma cells (MCF-7)|Cervical adenocarcinoma cells (HeLa)     24918059
CFL2
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -
Ribosome HEK-293 cells     22199352

Related Drug Information:


Resource Symbol Drug Name PubChem
ID		 Function
ncDR hsa-miR-30a-5p
4-Methyl-3-{[6-(Methylsulfonyl)quinolin-4-Yl]amino}phenol 9927432 Drug sensitive
2-(2,4-Difluorophenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione 9905583 Drug resistant
7-Epi-10-deacetylbaccatin III 9872117 Drug resistant
5-(5,6-Dimethoxy-1-benzimidazolyl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide 9826308 Drug resistant
Tiotixene 941651 Drug resistant
Cyclo[N-methyl-L-alanyl-beta-alanyl-(2R)-2-hydroxy-4-pentenoyl-L-prolyl-L-isoleucyl-N-methyl-L-valyl] 91746256 Drug resistant
(3R,10S,13S,16S,19R)-16-[(2S)-Butan-2-yl]-10,11,14-trimethyl-3-(2-methylpropyl)-13-propan-2-yl-4-oxa-1,8,11,14,17-pentazabicyclo[17.3.0]docosane-2,5,9,12,15,18-hexone 90471303 Drug resistant
Benzethonium chloride 8478 Drug resistant
Tanakan 83818 Drug resistant
Clothixamide maleate 76972759 Drug resistant
Secalonic acid D 73431 Drug resistant
Redoxal 72571 Drug resistant
Piperidinium pentamethylenedithiocarbamate 72508 Drug resistant
7-Hydroxystaurosporine 72271 Drug resistant
2-Butenoic acid, 2-methyl-, 2,3,3a,4,5,8,9,11a-octahydro-8-hydroxy-6-(hydroxymethyl)-10-methyl-3-methylene-2-oxocyclodeca(b)furan-4-yl ester, (3aR-(3aR*,4R*(Z),6Z,8S*,10E,11aR*))- 71586750 Drug resistant
Resorufin 69462 Drug resistant
Edatrexate 6917908 Drug resistant
Phosphotrienin 6913994 Drug resistant
Sulbentine 67686 Drug resistant
Dihydroartemisinyl ether, stereoisomer of NSC-685989 6712439 Drug resistant
2-Debenzoyl-2-(3',5'-difluorobenzoyl)-A-nortaxol 6712230 Drug resistant
NO Data IN this field 6711510 Drug resistant
Methylestradiol 66413 Drug resistant
Vicenistatin 6438888 Drug resistant
Verrucarin A 6326658 Drug resistant
Chalcone analog 6296717 Drug resistant
Verrucarin A, 3'-(acetyloxy)-7'-deoxo-2'-deoxy-4'-hydroxy-7'-(1-hydroxyethyl)- 5933240 Drug resistant
8B-Hydroxy-9B,10B-epoxyverrucarin A 5477536 Drug resistant
Iejimalide A. 5473233 Drug resistant
Tetrocarcin A, sodium salt 54724658 Drug resistant
Artelasticin 5471311 Drug resistant
3-Deazauridine 54684286 Drug resistant
6-(4-Ethylphenyl)-2-benzenesulfonamidepyridazine-3(2H)-one 54612980 Drug resistant
2,3-Dehydrosarcovagine D 54612860 Drug resistant
Tetracarboxyphthalocyanine-Gadolinium 54608636 Drug resistant
p-Chloranilinum[bis(p-chloraniline)dioxalatoruthenate(III)] 54608061 Drug resistant
2,10-Anthrylenedimethylene)-bis[2-thiopseudourea] dihydrochloride 54603799 Drug resistant
Cuspidatin C 5459164 Drug resistant
Thiram 5455 Drug resistant
(E)-1-(2,5-Dihydroxyphenyl)ethene-2-isonitrile 5388136 Drug resistant
Acetylrolandrolide 5384465 Drug resistant
Melampodin B acetate 5359212 Drug resistant
Ovatifolin acetate 5358419 Drug resistant
3-[(4-Methoxyphenyl)thio]-2H-isoindole-1-carbaldehyde 53361730 Drug resistant
3-[1-(2-Chlorophenyl)ethoxy]-5-(6-methoxybenzimidazol-1-yl)thiophene-2-carboxamide 53338698 Drug resistant
N-(5-Ethylsulfonyl-2-methoxyphenyl)-5-[3-(2-fluorophenyl)phenyl]-1,3-oxazol-2-amine 5329875 Drug sensitive
Herbimycin 5311102 Drug resistant
Cyclosporin A 5284373 Drug resistant
Erioflorin acetate 5281443 Drug resistant
Kekule 499328 Drug resistant
Pyrimethamine 4993 Drug resistant
Ammonia; dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498559 Drug resistant
Dichloroplatinum; 2-(4-methoxyphenyl)ethanamine 498558 Drug resistant
Staurosporine, 98% 49831000 Drug sensitive
Patulin 4696 Drug resistant
Mycophenolic acid 446541 Drug resistant
[(1R,2S,3S,5R,6R,8S,10E,12R,13S,15R,16S,17R,18S)-18-Benzyl-6-hydroxy-6,8,15,16-tetramethyl-7,20-dioxo-4,14-dioxa-19-azapentacyclo[10.8.0.01,17.03,5.013,15]icos-10-en-2-yl] acetate 44559501 Drug resistant
Oxyacanthine 442333 Drug resistant
Elephantopin 442206 Drug resistant
1-Benzyl-3-hexadecyl-2-methylimidazolium chloride 44219704 Drug resistant
Isobrucein A 441802 Drug resistant
Oridonin (thiol adduct OF) 432952 Drug resistant
10-Hydroxy-5-methoxy-1-(2-methyloxiran-2-yl)-1,2-dihydrofuro[2,3-c]xanthen-6-one 429905 Drug resistant
N-[p-[[(2,4-Diamino-6-quinazolinyl)methyl]amino]benzoyl]-L-aspartic acid 419263 Drug resistant
Aminopyrimidine-CH3 406278 Drug resistant
Triacetyl crambescidin 800 hydrochloride 400721 Drug resistant
2-((4-(((2,4-Diaminopteridin-6-yl)methyl)methylamino)phenyl)carbonylamino)-4-sulfobutanoic acid 393791 Drug resistant
Asimicinone 393461 Drug resistant
6H-Pyrido[2,3,4-kl]acridin-6-one, 4-methoxy- 391209 Drug resistant
Lapachol 3884 Drug resistant
Acetic acid,4,7,10-tetraazacyclododecane-1,7-diyl]bis 387352 Drug resistant
N-(2-Bromo-5-methoxybenzylidene)-6,7-dimethoxy-1-naphthalenamine 387181 Drug resistant
2,5-Bis(3-Amino-2,4,6-trinitrophenyl)-1,3,4-thiadiazole 385374 Drug resistant
Stereoisomer of NSC 674066-O 384359 Drug resistant
Hexanoic acid, 6-[(7-methoxy-1-nitro-9-acridinyl)amino]- 384253 Drug resistant
N8-Actinomycin D 383040 Drug resistant
4,5-Dimethyl-11H-pyrido[4,3-a]carbazole 382590 Drug resistant
7-Chloro-6-(2-fluoroethylamino)quinoline-5,8-dione 379079 Drug resistant
2-Amino-5,8-dihydroxy-1,4-naphthoquinone 377209 Drug resistant
3,8-Dimethyl-1,2-naphthoquinone 373912 Drug resistant
4-Methylthio-N-(3,4,5-trimethoxybenzyl)aniline 373808 Drug resistant
N-Hydroxy-N-methylpropanethioamide 371713 Drug resistant
4-(1-Benzofuran-2-yl)-7-methoxychromen-2-one 364364 Drug sensitive
4-Nitro-6-(trifluoromethyl)-2,1,3-benzoselenadiazole 362897 Drug resistant
3-Nitro-5-formylisoxazole 362479 Drug resistant
Discorhabdin C-nitrodienone . TFA 362394 Drug resistant
4-N,N-Bis-2'-cyanoethylaminobenzylidene-4-fluoro aniline 359414 Drug resistant
3-Deazaneplanocin hydrochloride 358176 Drug resistant
Imidazole, 1-(4-chlorophenyl)-4-(4-nitrophenyl)- 355940 Drug sensitive
5-(4-Azido-3-chlorophenyl)-6-ethylpyrimidine-2,4-diamine 353605 Drug resistant
Trimetrexate glucuronic acid salt 336805 Drug resistant
4-Selenazolecarboxamide, 2-beta-D-ribofuranosyl- 334706 Drug resistant
Predorine 333830 Drug resistant
2,4-Quinazolinediamine, 6-[[4-(dimethylamino)phenyl]thio]- 328145 Drug resistant
6-(4-Chlorophenyl)sulfanylquinazoline-2,4-diamine 328131 Drug resistant
Helenin 327378 Drug resistant
Dmask 32465 Drug resistant
Phomazarin 318385 Drug sensitive
1,4-Naphthalenedione, 5,8-dihydroxy-2,3-bis(hydroxymethyl)- 313371 Drug resistant
N,N-Dibenzyldaunorubicin 3081598 Drug resistant
Dasatinib 3062316 Drug sensitive
Stannane, trimethyl[(4-morpholinylthioxomethyl)thio]- 300936 Drug resistant
1,1-Dimethyl-5-(2-naphthalenyl)dithiobiuret 3004012 Drug resistant
2-Chloro-5-[4-[2-chloro-4-(4,6-diamino-2,2-dimethyl-1,3,5-triazin-1-yl)phenyl]butyl]benzenesulfonyl fluoride;ethanesulfonic acid 278692 Drug resistant
Dichloroallyl lawsone 277767 Drug resistant
Tamoxifen 2733526 Drug resistant
Carmofur 2577 Drug resistant
5-(1H-1,3-Benzodiazol-1-yl)-3-[(2-bromophenyl)methoxy]thiophene-2-carboxamide 25263083 Drug resistant
Hookerianamide J 25016666 Drug resistant
Hookerianamide K 25016412 Drug resistant
6-(p-Toluenesulfonylaminoethyl)diquino-1,4-thiazine 24858161 Drug sensitive
Hydrazine sulfate 24842 Drug resistant
Metoprine 24466 Drug resistant
4'-(1H-Benzimidazol-2-yl)1,1biphenyl-4-amine 24205338 Drug resistant
[(4E,6Z,10Z)-20,22-Dihydroxy-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3-oxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18(22),19-hexaen-9-yl] carbamate 24199492 Drug resistant
7-Fluoro-2-benzoyl-3-trifluoromethylquioxaline 1,4-dioxide 23635154 Drug resistant
Drostanolone propionate 224004 Drug resistant
6,7-Dimethoxy-4-(3-hydroxy-4-methylanilino)quinazoline hydrochloride 21701565 Drug sensitive
Diethylcarbamodithioic acid, sodium salt 21192315 Drug resistant
Erlotinib 176870 Drug sensitive
Phenethyl isothiocyanate 16741 Drug resistant
Chonemorphine 165208 Drug resistant
Dihydroartemisinin (mixture of alpha and beta isomers) 16399850 Drug resistant
Trihexyltetradecylphosphonium hexafluorophosphate 16212610 Drug resistant
N-(3-(1-Aziridinyl)propyl)-1,4-butanediamine 160394 Drug sensitive
Ammonium tetrathiomolybdate 15251598 Drug resistant
Solvent red 1 14678 Drug sensitive
N-[3-[(3-Amino-3-oxoprop-1-en-2-yl)amino]-3-oxoprop-1-en-2-yl]-2-[(1S)-18-[(2S)-2,3-dihydroxybutan-2-yl]-11-ethylidene-59-hydroxy-8,31-bis(1-hydroxyethyl)-26,46-dimethyl-40,43-dimethylidene-6,9,16,23,28,38,41,44,47-nonaoxo-37-propan-2-yl-27-oxa-3,13,20,56-tetrathia-7,10,17,24,36,39,42,45,48,52,58,61,62,63,64-pentadecazanonacyclo[23.23.9.329,35.12,5.112,15.119,22.154,57.01,53.032,60]tetrahexaconta-2(64),4,12(63),19(62),21,29(61),30,32(60),33,51,54,57-dodecaen-51-yl]-1,3-thiazole-4-carboxamide 146156820 Drug resistant
Methyl (7E,9Z,11S,12R,13S,14R,15R,17R,18S,19S,20E)-2,16-diacetyloxy-11,12,14,18,19,31-hexahydroxy-3,7,11,13,17,19,21,27-octamethyl-6,28-dioxo-23,25-dioxa-5-azatetracyclo[20.7.1.14,29.026,30]hentriaconta-1,3,7,9,20,22(30),26,29(31)-octaene-15-carboxylate 138319233 Drug resistant
Methyl (7E,9Z,11R,12S,13R,14R,15R,17R,18S,19S,20E)-2,16-diacetyloxy-12,14,18,19,31-pentahydroxy-3,7,11,13,17,19,21,27-octamethyl-6,28-dioxo-23,25-dioxa-5-azatetracyclo[20.7.1.14,29.026,30]hentriaconta-1,3,7,9,20,22(30),26,29(31)-octaene-15-carboxylate 138319083 Drug resistant
Triethyltin chloride 13820 Drug resistant
4-[[(1-Benzylpyrazolo[3,4-d]pyrimidin-4-yl)hydrazinylidene]methyl]-2-methoxyphenol 136091540 Drug sensitive
Astrazon Orange R 135747272 Drug resistant
C8, Carbonyl prodigiosine 135540857 Drug resistant
Roseophilin, HCl salt 135499311 Drug resistant
[(3S)-7-Oxo-6-[[(E,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methoxy-8-methyl-non-6-enoyl]amino]azepan-3-yl] tetradecanoate 134816767 Drug resistant
Actinomycin D, 93% 131954673 Drug resistant
Sendanin 12806435 Drug resistant
15-Deacetylsergeolide 125729 Drug resistant
Triphenyltin chloride 12540 Drug resistant
2,4-Pyrimidinediamine, 5-(3-azido-4-chlorophenyl)-6-ethyl- 125330 Drug resistant
10-Desacetylbaccatin III 125001 Drug resistant
Astraphloxin 12299852 Drug resistant
Rubroskyrin 119082 Drug resistant
(5S,7S)-5,7,9,10-Tetrahydroxy-2-methoxy-7-methyl-6,8-dihydro-5H-anthracene-1,4-dione 11209399 Drug resistant
Acetylenedicarboxamide 10971 Drug resistant
(S)-Morpholin-3-ylmethyl (4-((1-(3-fluorobenzyl)-1H-indazol-5-yl)amino)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl)carbamate 10437018 Drug sensitive
Cladospirone bisepoxide 10316810 Drug resistant
(3S,6S)-1,4-Dimethyl-3,6-bis[(2R)-3,3,3-trichloro-2-methylpropyl]piperazine-2,5-dione 101425118 Drug resistant
Erigerol 101318126 Drug resistant
(1s,2e,4s,6r,7e,10r,11e)-2,7,11-cembratriene-4,6,10-triol - Drug resistant
(E)-2-(2-(benzo[d][1,3]dioxol-5-yl)vinyl)-5-(3-methyl-1H-pyrazol-5-yl)-1,3,4-oxadiazole - Drug resistant
(E)-3-(3,5-dimethoxyphenyl)-1-(4-(quinazolin-4-ylamino)phenyl)prop-2-en-1-one - Drug resistant
(E)-8-(3,4,5-trimethoxybenzylidene)-4-(3,4,5-trimethoxyphenyl)-3,4,5,6,7,8-hexahydroquinazolin-2-amine - Drug resistant
(z) 2',3,4,5-tetramethoxystilbene - Drug resistant
(Z)-3-((1-(3,5-dimethoxyphenyl)-9H-pyrido[3,4-b]indol-3-yl)methylene)-5-methoxyindolin-2-one - Drug resistant
1-(naphthalen-2-yl)-2-(3,4,5-trimethoxyphenyl)-1h-imidazole - Drug resistant
1,2,3-thiadiazole, 5-[(4-chlorophenyl)sulfonyl]-4-phenyl- - Drug resistant
1,2-benzo-8-(d,l-alanyl)-3-phenoxazone nitrate salt - Drug resistant
1,4-benzenediamine (9ci), n-butyl-n'-phenyl- - Drug resistant
1,8-octanediamine, n,n'-di-9-acridinyl- (9ci) - Drug resistant
1-piperidinecarbodithioic acid, antimony complex - Drug resistant
2-chloro-3-amino-5,8-dihydoxy-1,4-naphthoquinone - Drug resistant
2-methoxy-4-(7-methoxy-2-phenylbenzo[d]imidazo[2,1-b][1,3]thiazol-3-yl)phenol - Drug resistant
3,19-(4-n,n-dimethylamino)benzylidineandrographolide - Drug resistant
3,19-benzylidine-14-deoxy-11,12-didehydroandrographolide - Drug resistant
4-(2-pyridinyl)-5h-1,2,3-dithiazole-5-thione - Drug resistant
4h,9h-naphtho[2,3-b]furan-2-carboxaldehyde, 4,9-dioxo- - Drug resistant
4-morpholinecarbodithioic acid, antimony complex - Drug resistant
4-piperidinone, 3,5-bis[(4-fluorophenyl)methylene]-, (e,e)- - Drug resistant
4-thiomorpholinecarbodithioic acid, antimony complex - Drug resistant
5,6,7,8-tetrafluoronaphtho[2,3-c][1,2,5]thiadiazole-4,9-dione - Drug resistant
5,6-dimethyl-9-oxo-9h-xanthene-4-acetic acid, sodium salt - Drug resistant
5-[2-(4-methoxyphenyl)ethyl]-1,2,3-dimethoxy benzene - Drug resistant
7-benzyl-5,7-dihydro-4h-isoxazolo[5,4-e]isoindole - Drug resistant
7-n,n-dimethylamino brefeldin a hydrochloride - Drug resistant
anthracen-9-one, 10-[(2-methoxyphenyl)methylene]- - Drug resistant
b676297k277 3',4'-deoxypsorospermin 3',4'-chlorohydrin - Drug resistant
cis-2-hydroxymethyl-4-(isocytosin-1'-yl)-1,3-dioxolane - Drug resistant
ethyl, methoxy, prodigisine - Drug resistant
gold(1+), bis(trimethylphosphine)-, chloride - Drug resistant
indoline, 5-chloro-1,3,3-trimethyl-2-methylene- (8ci) - Drug resistant
nsc 708781 incorporated in micelles, 0.55% (w/w) of drug - Drug resistant
nsc 708783 incorporated in micelles, 0.20% (w/w) of drug - Drug resistant
salicylaldehyde, 5-bromo- (8ci) - Drug resistant
thiourea, n-(1-ethylpropyl)-n'-[(2-thienyl)thioxomethyl]- - Drug resistant
uridine, 5-fluoro-, 2',3',5'-triacetate - Drug resistant
(-)-dactylolide - Drug resistant
(Z)-6-chloro-3-((2-(4-methoxyphenyl)-3H-benzo[d]imidazol-5-yl)methylene)indolin-2-one - Drug resistant
[bis(aminomethyl)diethylsilane]dichloroplatinum (ii) - Drug resistant
1-[(2-phenylethoxy)methyl]-5-ethyl-6-(phenylseleno)uracil - Drug resistant
2-(4-hydroxy-benzylidene)-2-(2-pyridyl)acetonitrile - Drug resistant
4'-chloro-3-nitro-o-salicylotoluidide - Drug resistant
Aminopterin Derivative - Drug resistant
antineoplastic-615538 - Drug resistant
antineoplastic-d665837 - Drug resistant
aromoline - Drug resistant
arylmethylene-f - Drug resistant
Basic Fuchsin - Drug resistant
bavachyaone - Drug resistant
dichlorobisoxinatotitanium(iv) - Drug resistant
erytroxytriol-p - Drug resistant
Methotrexate Derivative - Drug resistant
nitralamine hydrochloride(usan) - Drug resistant
obtained by culturing a strain of micromonospora - Drug resistant
pancratium littorale - Drug resistant
pyrazoline derivative - Drug resistant
secafascaplysin - Drug resistant
streptorubrin - Drug resistant
Tetraplatin - Drug resistant
tyrosine kinase inhibitor bte-16 (mw=221.24) - Drug resistant
1,3,6-triphenyl-oxazolo(5,4-d)pyrimidin-2',4(1h,3h)-dion - Drug sensitive
1,3-diphenyl-4-(3-phenyl-4,5-dihydro-1H-pyrazol-5-yl)-1H-pyrazole - Drug sensitive
1-naphthalenecarboxamide, n,n'-1,8-(octanediyl)bis- - Drug sensitive
6-phenyl-6h-indeno[1,2-c]isoquinoline-5,11-dione - Drug sensitive
indole-2,3-dione, 5-methyl-, 3-[(o-nitrophenyl)hydrazone] - Drug sensitive
pyrazino[1,2-a]benzimidazole, 1,3-diphenyl- - Drug sensitive
(-)-furodysinin - Drug sensitive
antineoplastic-d655481 - Drug sensitive
geldanamycin dimethylglycinate - Drug sensitive
toxin .delta.53l - Drug sensitive
Resource Symbol Drug Name PubChem
ID		 Function Link  
RNAInter hsa-miR-30a-5p
Oxaliplatine 6857599 Drug interaction    RC00000897
Gemcitabine 60750 Drug interaction    RC00000889
Sunitinib 5329102 Drug interaction    RC00000896
Eloxatine 5310940 Drug interaction    RC00000895
Imatinib 5291 Drug interaction    RC00000885
Docosahexaenoic acid 445580 Drug interaction    RC00000894
Paclitaxel 36314 Drug interaction    RC00000888
5-Fluorouracil 3385 Drug interaction    RC00000884
Enoxacin 3229 Drug interaction    RC00000883
Doxorubicin 31703 Drug interaction    RC00000887
cis-Diaminedichloroplatinum 2767 Drug interaction    RC00000882
Verapamil 2520 Drug interaction    RC00000881
Sorafenib 216239 Drug interaction    RC00000893
Polylysine 162282 Drug interaction    RC00000892
Arsenic trioxide 14888 Drug interaction    RC00000886
Docetaxel 148124 Drug interaction    RC00000891
Leucovorin 135403648 Drug interaction    RC00000898
3-Methyladenine 135398661 Drug interaction    RC00000880
Ginsenoside Rh2 119307 Drug interaction    RC00000890
Rituximab - Drug interaction    RC00000899
Trastuzumab - Drug interaction    RC00000900
1,2,6-Tri-O-galloyl-beta-D-glucopyranose - Drug interaction    RC00000901
Trypaflavine - Drug interaction    RC00000902
Chemotherapy - Drug interaction    RC00008824
Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-30a-5p
Cisplatin 5702198       27602140
Cisplatin 5702198       28222434
Cisplatin 5702198       28977798
Cisplatin 5702198       29642855
Etoposide 36462       28977798
Paclitaxel 36314       28487996
Erlotinib 176870       27895663
Gefitinib 123631       27895663

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-30a-5p
Interactor2: CFL2

Evidence Support:


Strong-Evidence qRT-PCR
Weak-Evidence miRNA array
Prediction-Evidence miRanda//PicTar//RNAHybrid//Targetscan
Support Database VIRmiRNA

References:


PMID 23418453 Target region 3'UTR
Source VIRmiRNA Interactor1 expression None
Tissue or cell line Huh7.5 cells Interactor2 expression None
Description Seven miRNAs (miR-30b, miR-30c, miR-130a, miR-192, miR-301, miR-324-5p, and miR-565) were down-regulated in HCV-infected Huh7.5 cells (p<0.05) and subsequently up-regulated following interferon-alpha treatment (p<0.01). The miR-30(a-d) cluster and miR-130a/301 and their putative mRNA targets were predicted to be associated with cellular pathways that involve Hepatitis C virus entry, propagation and host response to viral infection.

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