Basic Information:
VIRBase ID: HHID00019057
Virus: Duck Tembusu virus
Host: Anas platyrhynchos
Confidence Score: 0.9630
Interaction Type: Host-Host interaction
Interactor Information:
Interactor1
Interactor2
Symbol
apl-miR-221-3p
SOCS5
miRBase Accession/Entrez ID
apl-miR-221-3p
101798051
Organism
Anas platyrhynchos
Anas platyrhynchos
Category
miRNA
mRNA
Alias
-
Anapl_08358
Interaction Network (The top 100 interactions) :
Interactor1: apl-miR-221-3p
Interactor2: SOCS5
Evidence Support:
Strong-Evidence
Luciferase reporter assay//qRT-PCR//Western blot
Prediction-Evidence
miRanda//RNAHybrid
Support Database
ViRBase
References:
PMID
32373087
Target region
3'UTR
Source
ViRBase
Interactor1 expression
Upregulation
Tissue or cell line
DEF cells
Interactor2 expression
None
Description
Besides, we further proved that SOCS5 is a target of miR-221-3p and that miR-221-3p could negatively modulate SOCS5 expression at both mRNA and protein levels.