Detail Information

Basic Information:


  VIRBase ID:  

HHID00019057

  Virus:  

Duck Tembusu virus

  Host:  

Anas platyrhynchos

  Confidence Score:  

0.9630

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol apl-miR-221-3p SOCS5
miRBase
Accession/Entrez ID
apl-miR-221-3p 101798051
Organism Anas platyrhynchos Anas platyrhynchos
Category miRNA mRNA
Alias - Anapl_08358

Interaction Network (The top 100 interactions):


Interactor1: apl-miR-221-3p
Interactor2: SOCS5

Evidence Support:


Strong-Evidence Luciferase reporter assay//qRT-PCR//Western blot
Prediction-Evidence miRanda//RNAHybrid
Support Database ViRBase

References:


PMID 32373087 Target region 3'UTR
Source ViRBase Interactor1 expression Upregulation
Tissue or cell line DEF cells Interactor2 expression None
Description Besides, we further proved that SOCS5 is a target of miR-221-3p and that miR-221-3p could negatively modulate SOCS5 expression at both mRNA and protein levels.

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