Basic Information: VIRBase ID: HHID00019054 Virus: Duck Tembusu virus Host: Anas platyrhynchos Confidence Score: 0.9860 Interaction Type: Host-Host interaction
Interactor Information:
Interactor1
Interactor2
Symbol
apl-miR-148a-5p TLR3
miRBase
apl-miR-148a-5p
101790771
Organism
Anas platyrhynchos
Anas platyrhynchos
Category
miRNA
mRNA
Alias
-
Anapl_09935//TLR-3
Interaction Network (The top 100 interactions) :
Interactor1: apl-miR-148a-5p
Interactor2: TLR3
Evidence Support:
Strong-Evidence
Dual luciferase reporter assay//ELISA//qRT-PCR//Western blot
Prediction-Evidence
miRanda//RNAHybrid
Support Database
ViRBase
References:
PMID
31947624 Target region
None
Source
ViRBase
Interactor1 expression
None
Tissue or cell line
Duck embryos DEF cells
Interactor2 expression
None
Description
Then we found miR-148a-5p can target TLR3 and down-regulate the expression of TLR3, serving as a negative factor in innate immunity. DTMUV-Infected DEF Cells and DEF-Derived Exosomes Show Decreased Levels of miR-148a-5p.
