Basic Information:

  VIRBase ID:  

HHID00018966

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:  MIMAT0026482          SERTM1:  NM_203451     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-190a-3p	SERTM1
miRBase Accession/Entrez ID	MIMAT0026482	400120
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	C13orf36

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-190a-3p	rs1367478528 chr15:62824008    C/T rs146591219 chr15:62824027    C/T rs1311298147 chr15:62824010    A/G rs771043955 chr15:62824015    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	SERTM1	chr13:37262539(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SERTM1	chr13:37269121-37269122(+) m6A 5'UTR       24981863 chr13:37269223-37269224(+) m6A CDS       25456834//24981863//22608085 chr13:37269266-37269267(+) m6A CDS       25456834//24981863//22608085 chr13:37269309-37269310(+) m6A CDS       22608085 chr13:37269525-37269526(+) m6A CDS       - chr13:37269711-37269712(+) m6A 3'UTR       22608085 chr13:37269739-37269740(+) m6A 3'UTR       25456834//22608085 chr13:37269783-37269784(+) m6A 3'UTR       25456834//22608085 chr13:37269867-37269868(+) m6A 3'UTR       25456834//24981863//22608085 chr13:37269873-37269874(+) m6A 3'UTR       25456834//24981863//22608085 chr13:37269925-37269926(+) m6A 3'UTR       25456834//24981863//22608085 chr13:37269988-37269989(+) m6A 3'UTR       25456834//22608085 chr13:37269995-37269996(+) m6A 3'UTR       25456834//22608085 chr13:37270045-37270046(+) m6A 3'UTR       22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-190a-3p	Exosome Plasma     23663360 Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	SERTM1	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-190a-3p
Interactor2: SERTM1

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	DIANA-microT//miRDB//Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).