Basic Information:

  VIRBase ID:  

HHID00018927

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:  MIMAT0026482          ZNF284:  NM_001037813     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-190a-3p	ZNF284
miRBase Accession/Entrez ID	MIMAT0026482	342909
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	ZNF284L

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-190a-3p	rs1367478528 chr15:62824008    C/T rs146591219 chr15:62824027    C/T rs1311298147 chr15:62824010    A/G rs771043955 chr15:62824015    T/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZNF284	chr19:44577771(+) A-I      intronic chr19:44577837(+) A-I      intronic chr19:44577886(+) A-I      intronic chr19:44582665(+) A-I      intronic chr19:44578926(+) A-I      intronic chr19:44582744(+) A-I      intronic chr19:44582748(+) A-I      intronic chr19:44577716(+) A-I      intronic chr19:44578385(+) A-I      intronic chr19:44578408(+) A-I      intronic chr19:44578412(+) A-I      intronic chr19:44583675(+) A-I      intronic chr19:44583961(+) A-I      intronic chr19:44578311(+) A-I      intronic chr19:44577740(+) A-I      intronic chr19:44577728(+) A-I      intronic chr19:44578317(+) A-I      intronic chr19:44578363(+) A-I      intronic chr19:44582754(+) A-I      intronic chr19:44579157(+) A-I      intronic chr19:44578320(+) A-I      intronic chr19:44577908(+) A-I      intronic chr19:44577814(+) A-I      intronic chr19:44578331(+) A-I      intronic chr19:44578866(+) A-I      intronic chr19:44579032(+) A-I      intronic chr19:44577830(+) A-I      intronic chr19:44577790(+) A-I      intronic chr19:44578455(+) A-I      intronic chr19:44578936(+) A-I      intronic chr19:44578463(+) A-I      intronic chr19:44577758(+) A-I      intronic chr19:44578935(+) A-I      intronic chr19:44577840(+) A-I      intronic chr19:44578867(+) A-I      intronic chr19:44579074(+) A-I      intronic chr19:44578960(+) A-I      intronic chr19:44579033(+) A-I      intronic chr19:44578456(+) A-I      intronic

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZNF284	chr19:44589880-44589881(+) m6A CDS       - chr19:44589904-44589905(+) m6A CDS       - chr19:44589909-44589910(+) m6A CDS       - chr19:44589945-44589946(+) m6A CDS       24284625 chr19:44589969-44589970(+) m6A CDS       24284625 chr19:44589977-44589978(+) m6A CDS       24284625 chr19:44590038-44590039(+) m6A CDS       24284625//24981863 chr19:44590063-44590064(+) m6A CDS       24284625//24981863 chr19:44590274-44590275(+) m6A CDS       - chr19:44590288-44590289(+) m6A CDS       - chr19:44590317-44590318(+) m6A CDS       - chr19:44590637-44590638(+) m6A CDS       24981863//22608085 chr19:44590653-44590654(+) m6A CDS       24981863//22608085 chr19:44590721-44590722(+) m6A CDS       24981863//22608085 chr19:44590733-44590734(+) m6A CDS       24981863//22608085 chr19:44590794-44590795(+) m6A CDS       24209618//24981863//22608085 chr19:44590819-44590820(+) m6A CDS       24284625//24981863//22608085 chr19:44590905-44590906(+) m6A CDS       24284625//24209618//24981863//27773535//22608085 chr19:44590989-44590990(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr19:44591046-44591047(+) m6A CDS       24284625//24209618//24981863//22608085 chr19:44591055-44591056(+) m6A CDS       24284625//24209618//24981863//22608085 chr19:44591073-44591074(+) m6A CDS       24284625//24209618//24981863//22608085 chr19:44591121-44591122(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr19:44591223-44591224(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr19:44591241-44591242(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr19:44591297-44591298(+) m6A CDS       24284625//24209618//25456834//24981863//22575960//22608085 chr19:44591326-44591327(+) m6A CDS       24284625//24209618//25456834//24981863//22608085 chr19:44591342-44591343(+) m6A CDS       24284625//24209618//25456834//24981863//22608085

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-190a-3p	Exosome Plasma     23663360 Exosome Plasma     24683445 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
	ZNF284	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-190a-3p
Interactor2: ZNF284

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).