Detail Information

Basic Information:


  VIRBase ID:  

HHID00018825

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           BMPER:      

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Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p BMPER
miRBase
Accession/Entrez ID
MIMAT0026482 168667
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CRIM3//CV-2//CV2

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR BMPER
chr7:34160257(+) A-I      intronic
chr7:34063774(+) A-I      intronic
chr7:34063794(+) A-I      intronic
chr7:34063805(+) A-I      intronic
chr7:34063814(+) A-I      intronic
chr7:33994553(+) A-I      intronic
chr7:33994558(+) A-I      intronic
chr7:33994566(+) A-I      intronic
chr7:34003346(+) A-I      intronic
chr7:34003350(+) A-I      intronic
chr7:34151951(+) A-I      intronic
chr7:34063768(+) A-I      intronic
chr7:34160085(+) A-I      intronic
chr7:34063823(+) A-I      intronic
chr7:34160091(+) A-I      intronic
chr7:34151505(+) A-I      intronic
chr7:34063817(+) A-I      intronic
chr7:34003349(+) A-I      intronic
chr7:34063876(+) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase BMPER
chr7:34118524-34118525(+) m6A CDS//intron       24981863
chr7:34118567-34118568(+) m6A CDS//intron       24981863
chr7:34118623-34118624(+) m6A CDS//intron       24981863
chr7:34118641-34118642(+) m6A CDS//intron       24981863
chr7:34125391-34125392(+) m6A CDS//exon       24981863
chr7:34125464-34125465(+) m6A CDS//exon       24981863//22608085
chr7:34125499-34125500(+) m6A CDS//exon       24981863//22608085
chr7:34125566-34125567(+) m6A CDS//exon       25456834//24981863
chr7:34125590-34125591(+) m6A CDS//exon       25456834//24981863
chr7:34125603-34125604(+) m6A CDS//exon       25456834//24981863
chr7:34192829-34192830(+) m6A CDS       24981863
chr7:34192905-34192906(+) m6A 3'UTR       24981863
chr7:34192954-34192955(+) m6A 3'UTR       24981863
chr7:34192984-34192985(+) m6A 3'UTR       24981863
chr7:34193035-34193036(+) m6A 3'UTR       24981863
chr7:34193055-34193056(+) m6A 3'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
BMPER
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: BMPER

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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