Detail Information

Basic Information:


  VIRBase ID:  

HHID00018751

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           NANP:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p NANP
miRBase
Accession/Entrez ID		 MIMAT0026482 140838
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - C20orf147//dJ694B14.3//HDHD4

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NANP
chr20:25597612(-) A-I      intronic
chr20:25597579(-) A-I      intronic
chr20:25595499(-) A-I      3'UTR
chr20:25600037(-) A-I      intronic
chr20:25595496(-) A-I      3'UTR
chr20:25595420(-) A-I      3'UTR
chr20:25598428(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NANP
chr20:25596585-25596586(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr20:25596730-25596731(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25596759-25596760(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25596815-25596816(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25596898-25596899(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25596906-25596907(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25596947-25596948(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22575960//22608085
chr20:25597060-25597061(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr20:25597090-25597091(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr20:25597142-25597143(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr20:25597208-25597209(-) m6A CDS       24209618//24981863//27773535//22608085
chr20:25604543-25604544(-) m6A CDS       24209618//24981863//27371828//22608085
chr20:25604721-25604722(-) m6A 5'UTR       24981863
chr20:25604777-25604778(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
NANP
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: NANP

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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