Detail Information

Basic Information:


  VIRBase ID:  

HHID00018648

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           ZIC5:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p ZIC5
miRBase
Accession/Entrez ID		 MIMAT0026482 85416
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZIC5
chr13:100615543-100615544(-) m6A 3'UTR       24981863
chr13:100615553-100615554(-) m6A 3'UTR       24981863
chr13:100615583-100615584(-) m6A 3'UTR       24981863
chr13:100616808-100616809(-) m6A 3'UTR       24981863
chr13:100616819-100616820(-) m6A 3'UTR       24981863
chr13:100617091-100617092(-) m6A 3'UTR       24284625//22608085
chr13:100617123-100617124(-) m6A 3'UTR       24284625//22608085
chr13:100617218-100617219(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr13:100617391-100617392(-) m6A 3'UTR       25456834//24981863//27773535//22608085
chr13:100617404-100617405(-) m6A 3'UTR       25456834//24981863//27773535//22608085
chr13:100617415-100617416(-) m6A 3'UTR       25456834//24981863//27773535//22608085
chr13:100617487-100617488(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr13:100617529-100617530(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr13:100617546-100617547(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22608085
chr13:100617563-100617564(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085
chr13:100617581-100617582(-) m6A 3'UTR       24284625//25456834//24981863//26404942//27773535//22608085
chr13:100617658-100617659(-) m6A CDS       24284625//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr13:100617683-100617684(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr13:100617695-100617696(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//22575960//22608085
chr13:100617811-100617812(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr13:100617845-100617846(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr13:100617870-100617871(-) m6A CDS       24284625//25456834//24981863//27773535//22575960//22608085
chr13:100618002-100618003(-) m6A CDS       24284625//27773535//22608085
chr13:100622629-100622630(-) m6A CDS       25456834
chr13:100623324-100623325(-) m6A CDS       25456834//24981863//27773536
chr13:100623342-100623343(-) m6A CDS       25456834//24981863//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
ZIC5
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: ZIC5

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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