Detail Information

Basic Information:


  VIRBase ID:  

HHID00018491

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.6002

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           DDX55:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p DDX55
miRBase
Accession/Entrez ID		 MIMAT0026482 57696
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR DDX55
chr12:124090866(+) A-I      intronic
chr12:124088371(+) A-I      intronic
chr12:124090856(+) A-I      intronic
chr12:124088561(+) A-I      intronic
chr12:124089830(+) A-I      intronic
chr12:124089760(+) A-I      intronic
chr12:124088714(+) A-I      intronic
chr12:124101576(+) A-I      intronic
chr12:124101603(+) A-I      intronic
chr12:124088139(+) A-I      intronic
chr12:124089832(+) A-I      intronic
chr12:124101606(+) A-I      intronic
chr12:124088467(+) A-I      intronic
chr12:124088715(+) A-I      intronic
chr12:124088889(+) A-I      intronic
chr12:124089739(+) A-I      intronic
chr12:124101521(+) A-I      intronic
chr12:124089805(+) A-I      intronic
chr12:124088835(+) A-I      intronic
chr12:124088077(+) A-I      intronic
chr12:124097258(+) A-I      intronic
chr12:124101560(+) A-I      intronic
chr12:124088211(+) A-I      intronic
chr12:124088475(+) A-I      intronic
chr12:124088816(+) A-I      intronic
chr12:124089792(+) A-I      intronic
chr12:124104916(+) A-I      3'UTR
chr12:124104908(+) A-I      3'UTR
chr12:124088454(+) A-I      intronic
chr12:124088698(+) A-I      intronic
chr12:124090812(+) A-I      intronic
chr12:124088039(+) A-I      intronic
chr12:124090798(+) A-I      intronic
chr12:124088840(+) A-I      intronic
chr12:124089741(+) A-I      intronic
chr12:124089742(+) A-I      intronic
chr12:124089667(+) A-I      intronic
chr12:124088369(+) A-I      intronic
chr12:124089743(+) A-I      intronic
chr12:124088406(+) A-I      intronic
chr12:124088772(+) A-I      intronic
chr12:124088489(+) A-I      intronic
chr12:124088826(+) A-I      intronic
chr12:124088834(+) A-I      intronic
chr12:124089831(+) A-I      intronic
chr12:124090789(+) A-I      intronic
chr12:124088449(+) A-I      intronic
chr12:124088856(+) A-I      intronic
chr12:124097289(+) A-I      intronic
chr12:124088476(+) A-I      intronic
chr12:124088739(+) A-I      intronic
chr12:124088450(+) A-I      intronic
chr12:124088621(+) A-I      intronic
chr12:124088680(+) A-I      intronic
chr12:124088857(+) A-I      intronic
chr12:124088853(+) A-I      intronic
chr12:124088126(+) A-I      intronic
chr12:124089606(+) A-I      intronic
chr12:124088721(+) A-I      intronic
chr12:124088559(+) A-I      intronic
chr12:124088609(+) A-I      intronic
chr12:124088753(+) A-I      intronic
chr12:124089685(+) A-I      intronic
chr12:124097327(+) A-I      intronic
chr12:124088608(+) A-I      intronic
chr12:124088550(+) A-I      intronic
chr12:124089754(+) A-I      intronic
chr12:124090843(+) A-I      intronic
chr12:124088908(+) A-I      intronic
chr12:124088904(+) A-I      intronic
chr12:124101469(+) A-I      intronic
chr12:124088072(+) A-I      intronic
chr12:124101496(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED DDX55
chr12:124088450(+) A-I intron -    22327324
chr12:124088698(+) A-I intron -    22327324
chr12:124088467(+) A-I intron -    21960545
chr12:124088772(+) A-I intron -    21960545
chr12:124090798(+) A-I intron -    21960545
chr12:124088072(+) A-G intron -    22484847
chr12:124088077(+) A-G intron -    22484847
chr12:124088211(+) A-G intron -    22484847
chr12:124088369(+) A-G intron -    22484847
chr12:124088450(+) A-G intron -    22484847
chr12:124088467(+) A-G intron -    22484847
chr12:124088476(+) A-G intron -    22484847
chr12:124088698(+) A-G intron -    22484847
chr12:124088739(+) A-G intron -    22484847
chr12:124088834(+) A-G intron -    22484847
chr12:124088835(+) A-G intron -    22484847
chr12:124088908(+) A-G intron -    22484847
chr12:124089743(+) A-G intron -    22484847
chr12:124089832(+) A-G intron -    22484847
chr12:124090798(+) A-G intron -    22484847
chr12:124088396(+) T-C intron -    22484847
chr12:124088550(+) A-G intron -    22484847
chr12:124088609(+) A-G intron -    22484847
chr12:124088621(+) A-G intron -    22484847
chr12:124088715(+) A-G intron -    22484847
chr12:124088721(+) A-G intron -    22484847
chr12:124088816(+) A-G intron -    22484847
chr12:124088856(+) A-G intron -    22484847
chr12:124088857(+) A-G intron -    22484847
chr12:124088889(+) A-G intron -    22484847
chr12:124089685(+) A-G intron -    22484847
chr12:124089792(+) A-G intron -    22484847
chr12:124090812(+) A-G intron -    22484847
chr12:124091231(+) A-G intron -    22484847
chr12:124091358(+) A-G intron -    22484847
chr12:124091384(+) A-G intron -    22484847
chr12:124091385(+) A-G intron -    22484847
chr12:124103839(+) T-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase DDX55
chr12:124090183-124090184(+) m6A exon//intron       -
chr12:124090191-124090192(+) m6A exon//intron       -
chr12:124090598-124090599(+) m6A exon//intron       -
chr12:124090604-124090605(+) m6A exon//intron       -
chr12:124090637-124090638(+) m6A 3'UTR//CDS//exon//intron       -
chr12:124097781-124097782(+) m6A 3'UTR//CDS//exon       27773535
chr12:124104135-124104136(+) m6A CDS//exon       24981863//27773535//22608085
chr12:124104163-124104164(+) m6A CDS//exon       24981863//27773535//22608085
chr12:124104532-124104533(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104542-124104543(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104560-124104561(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104572-124104573(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104636-124104637(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104645-124104646(+) m6A CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104705-124104706(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104715-124104716(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104782-124104783(+) m6A 3'UTR       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr12:124104870-124104871(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr12:124104966-124104967(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124104978-124104979(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124104988-124104989(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124105003-124105004(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124105011-124105012(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124105016-124105017(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr12:124105406-124105407(+) m6A 3'UTR       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
DDX55
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: DDX55

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//miRDB//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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