Detail Information

Basic Information:


  VIRBase ID:  

HHID00018478

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           NCEH1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p NCEH1
miRBase
Accession/Entrez ID		 MIMAT0026482 57552
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - AADACL1//NCEH

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR NCEH1
chr3:172413634(-) A-I      intronic
chr3:172409680(-) A-I      intronic
chr3:172409675(-) A-I      intronic
chr3:172409653(-) A-I      intronic
chr3:172409555(-) A-I      intronic
chr3:172409550(-) A-I      intronic
chr3:172409495(-) A-I      intronic
chr3:172407449(-) A-I      intronic
chr3:172407111(-) A-I      intronic
chr3:172368123(-) A-I      intronic
chr3:172368113(-) A-I      intronic
chr3:172356894(-) A-I      intronic
chr3:172356869(-) A-I      intronic
chr3:172356861(-) A-I      intronic
chr3:172374706(-) A-I      intronic
chr3:172374705(-) A-I      intronic
chr3:172374697(-) A-I      intronic
chr3:172374691(-) A-I      intronic
chr3:172374643(-) A-I      intronic
chr3:172413682(-) A-I      intronic
chr3:172423639(-) A-I      intronic
chr3:172423621(-) A-I      intronic
chr3:172423620(-) A-I      intronic
chr3:172423541(-) A-I      intronic
chr3:172419533(-) A-I      intronic
chr3:172419449(-) A-I      intronic
chr3:172418491(-) A-I      intronic
chr3:172418478(-) A-I      intronic
chr3:172418431(-) A-I      intronic
chr3:172417612(-) A-I      intronic
chr3:172416004(-) A-I      intronic
chr3:172415000(-) A-I      intronic
chr3:172410182(-) A-I      intronic
chr3:172419526(-) A-I      intronic
chr3:172369452(-) A-I      intronic
chr3:172426284(-) A-I      intronic
chr3:172417464(-) A-I      intronic
chr3:172413490(-) A-I      intronic
chr3:172358875(-) A-I      intronic
chr3:172419355(-) A-I      intronic
chr3:172418556(-) A-I      intronic
chr3:172374510(-) A-I      intronic
chr3:172419378(-) A-I      intronic
chr3:172414970(-) A-I      intronic
chr3:172402925(-) A-I      intronic
chr3:172417572(-) A-I      intronic
chr3:172425473(-) A-I      intronic
chr3:172374473(-) A-I      intronic
chr3:172410269(-) A-I      intronic
chr3:172415945(-) A-I      intronic
chr3:172355380(-) A-I      intronic
chr3:172413672(-) A-I      intronic
chr3:172418496(-) A-I      intronic
chr3:172409625(-) A-I      intronic
chr3:172413529(-) A-I      intronic
chr3:172413491(-) A-I      intronic
chr3:172387528(-) A-I      intronic
chr3:172411902(-) A-I      intronic
chr3:172407187(-) A-I      intronic
chr3:172417646(-) A-I      intronic
chr3:172409483(-) A-I      intronic
chr3:172411786(-) A-I      intronic
chr3:172418534(-) A-I      intronic
chr3:172405881(-) A-I      intronic
chr3:172411808(-) A-I      intronic
chr3:172417452(-) A-I      intronic
chr3:172410236(-) A-I      intronic
chr3:172413622(-) A-I      intronic
chr3:172409613(-) A-I      intronic
chr3:172417470(-) A-I      intronic
chr3:172413658(-) A-I      intronic
chr3:172426274(-) A-I      intronic
chr3:172424426(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED NCEH1
chr3:172413490(-) A-I intron -    15342557
chr3:172413491(-) A-I intron -    15342557
chr3:172413622(-) A-I intron -    15342557
chr3:172413658(-) A-I intron -    15342557
chr3:172413672(-) A-I intron -    15342557
chr3:172373849(-) A-G intron -    22484847
chr3:172373914(-) A-G intron -    22484847
chr3:172392158(-) C-T intron -    22484847
chr3:172409483(-) A-G intron -    22484847
chr3:172409613(-) A-G intron -    22484847
chr3:172409625(-) A-G intron -    22484847
chr3:172410236(-) A-G intron -    22484847
chr3:172413529(-) A-G intron -    22484847
chr3:172413651(-) A-G intron -    22484847
chr3:172413658(-) A-G intron -    22484847
chr3:172418360(-) A-G intron -    22484847
chr3:172418390(-) A-G intron -    22484847
chr3:172418496(-) A-G intron -    22484847
chr3:172426274(-) A-G intron -    22484847
chr3:172426284(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NCEH1
chr3:172348651-172348652(-) m6A 3'UTR       27773535
chr3:172349733-172349734(-) m6A 3'UTR       27773535
chr3:172349752-172349753(-) m6A 3'UTR       27773535
chr3:172350699-172350700(-) m6A 3'UTR       27773535
chr3:172350715-172350716(-) m6A 3'UTR       27773535
chr3:172350792-172350793(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr3:172350868-172350869(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22575960//22608085
chr3:172350973-172350974(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:172350980-172350981(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr3:172351070-172351071(-) m6A 3'UTR       24284625//24209618//24981863//26404942//27773535//22608085
chr3:172351203-172351204(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351254-172351255(-) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr3:172351271-172351272(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr3:172351305-172351306(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//27773536//22575960//22608085
chr3:172351473-172351474(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351502-172351503(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351575-172351576(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351595-172351596(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351626-172351627(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351631-172351632(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351730-172351731(-) m6A CDS//exon       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr3:172351775-172351776(-) m6A CDS//exon       24284625//24209618//24981863//27773535//22575960//22608085
chr3:172351846-172351847(-) m6A 3'UTR//CDS//exon       24284625//24981863//27773535//22608085
chr3:172353711-172353712(-) m6A 3'UTR//CDS//exon       27773535
chr3:172365785-172365786(-) m6A CDS//intron       27773535
chr3:172428953-172428954(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
NCEH1
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: NCEH1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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