Detail Information

Basic Information:


  VIRBase ID:  

HHID00017916

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           SHOC2:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p SHOC2
miRBase
Accession/Entrez ID		 MIMAT0026482 8036
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - NSLH1//SIAA0862//SOC2//SUR8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR SHOC2
chr10:112685364(+) A-I      intronic
chr10:112685398(+) A-I      intronic
chr10:112757954(+) A-I      intronic
chr10:112735810(+) A-I      intronic
chr10:112685436(+) A-I      intronic
chr10:112685491(+) A-I      intronic
chr10:112756135(+) A-I      intronic
chr10:112736322(+) A-I      intronic
chr10:112746361(+) A-I      intronic
chr10:112757796(+) A-I      intronic
chr10:112684587(+) A-I      intronic
chr10:112684678(+) A-I      intronic
chr10:112685261(+) A-I      intronic
chr10:112685328(+) A-I      intronic
chr10:112685334(+) A-I      intronic
chr10:112761523(+) A-I      intronic
chr10:112758031(+) A-I      intronic
chr10:112685252(+) A-I      intronic
chr10:112685345(+) A-I      intronic
chr10:112736309(+) A-I      intronic
chr10:112761692(+) A-I      intronic
chr10:112720482(+) A-I      intronic
chr10:112764791(+) A-I      intronic
chr10:112685346(+) A-I      intronic
chr10:112735055(+) A-I      intronic
chr10:112684750(+) A-I      intronic
chr10:112759280(+) A-I      intronic
chr10:112685424(+) A-I      intronic
chr10:112760972(+) A-I      intronic
chr10:112720618(+) A-I      intronic
chr10:112761759(+) A-I      intronic
chr10:112684613(+) A-I      intronic
chr10:112685453(+) A-I      intronic
chr10:112684670(+) A-I      intronic
chr10:112684669(+) A-I      intronic
chr10:112761636(+) A-I      intronic
chr10:112685492(+) A-I      intronic
chr10:112685451(+) A-I      intronic
chr10:112699076(+) A-I      intronic
chr10:112685450(+) A-I      intronic
chr10:112685444(+) A-I      intronic
chr10:112764790(+) A-I      intronic
chr10:112685458(+) A-I      intronic
chr10:112685435(+) A-I      intronic
chr10:112685437(+) A-I      intronic
chr10:112732369(+) A-I      intronic
chr10:112702183(+) A-I      intronic
chr10:112684590(+) A-I      intronic
chr10:112759294(+) A-I      intronic
chr10:112687872(+) A-I      intronic
chr10:112699187(+) A-I      intronic
chr10:112684570(+) A-I      intronic
chr10:112685405(+) A-I      intronic
chr10:112685315(+) A-I      intronic
chr10:112684677(+) A-I      intronic
chr10:112684618(+) A-I      intronic
chr10:112684679(+) A-I      intronic
chr10:112728450(+) A-I      intronic
chr10:112699199(+) A-I      intronic
chr10:112684682(+) A-I      intronic
chr10:112764860(+) A-I      intronic
chr10:112761095(+) A-I      intronic
chr10:112685381(+) A-I      intronic
chr10:112759279(+) A-I      intronic
chr10:112685356(+) A-I      intronic
chr10:112685380(+) A-I      intronic
chr10:112685316(+) A-I      intronic
chr10:112685489(+) A-I      intronic
chr10:112696792(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED SHOC2
chr10:112696792(+) A-I intron -    22327324

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase SHOC2
chr10:112679797-112679798(+) m6A exon//intron       24981863
chr10:112723884-112723885(+) m6A 5'UTR//exon//intron       24981863
chr10:112724144-112724145(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr10:112724241-112724242(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr10:112724248-112724249(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr10:112724282-112724283(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr10:112724342-112724343(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr10:112724356-112724357(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr10:112724432-112724433(+) m6A CDS//exon//intron       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr10:112724496-112724497(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr10:112724655-112724656(+) m6A CDS//intron       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr10:112724744-112724745(+) m6A CDS//intron       24284625//24209618//24981863//26404942//22575960//22608085
chr10:112724753-112724754(+) m6A CDS//intron       24284625//24209618//24981863//26404942//22575960//22608085
chr10:112724763-112724764(+) m6A CDS//intron       24284625//24209618//24981863//22575960//22608085
chr10:112724789-112724790(+) m6A CDS//exon//intron       24284625//24981863//22575960//22608085
chr10:112724799-112724800(+) m6A CDS//exon//intron       24284625//24981863//22575960//22608085
chr10:112745434-112745435(+) m6A CDS//exon//intron       22608085
chr10:112745457-112745458(+) m6A CDS//exon//intron       22608085
chr10:112745497-112745498(+) m6A CDS//exon//intron       -
chr10:112745505-112745506(+) m6A CDS//exon//intron       -
chr10:112771475-112771476(+) m6A CDS       24284625

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
SHOC2
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: SHOC2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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