Detail Information

Basic Information:


  VIRBase ID:  

HHID00017860

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           TPR:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p TPR
miRBase
Accession/Entrez ID		 MIMAT0026482 7175
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase TPR
chr1:186281707-186281708(-) m6A 3'UTR       27773535
chr1:186281713-186281714(-) m6A 3'UTR       27773535
chr1:186281822-186281823(-) Y 3'UTR       26075521
chr1:186283011-186283012(-) m6A 3'UTR       24981863//27773535
chr1:186283027-186283028(-) m6A 3'UTR       24981863//27773535
chr1:186283090-186283091(-) m6A 3'UTR       24981863//28052920//27773535
chr1:186283121-186283122(-) m6A CDS       24981863//28052920//27773535
chr1:186283767-186283768(-) m6A CDS       24981863//26404942//27773535
chr1:186283797-186283798(-) m6A CDS       24981863//27773535
chr1:186283808-186283809(-) m6A CDS       24981863//27773535
chr1:186283815-186283816(-) m6A CDS       24981863//27773535
chr1:186287630-186287631(-) m6A CDS       27773535
chr1:186287694-186287695(-) m6A CDS//exon       27773535
chr1:186292829-186292830(-) m6A CDS       -
chr1:186292862-186292863(-) m6A CDS       -
chr1:186292919-186292920(-) m6A CDS       -
chr1:186292946-186292947(-) m6A CDS       -
chr1:186294667-186294668(-) m6A exon//intron       -
chr1:186294900-186294901(-) m6A CDS//exon       24981863//28052920//27773535
chr1:186294955-186294956(-) m6A CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr1:186294973-186294974(-) m6A CDS//exon       24209618//24981863//28052920//26404942//27773535//22575960//22608085
chr1:186295282-186295283(-) m6A CDS//exon       24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:186296597-186296598(-) m6A CDS       24209618//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr1:186296625-186296626(-) m1A CDS       26863196
chr1:186296746-186296747(-) m6A CDS       24981863//27773535
chr1:186296757-186296758(-) m6A CDS       24981863//26404942//27773535
chr1:186300670-186300671(-) m6A CDS       26404942//27773535
chr1:186301331-186301332(-) m6A CDS       26404942//27773535
chr1:186302500-186302501(-) m6A CDS       27773535
chr1:186303650-186303651(-) m6A CDS       24981863//27773535
chr1:186304227-186304228(-) m6A CDS       24981863//27773535
chr1:186304243-186304244(-) m6A CDS       24981863//27773535
chr1:186304252-186304253(-) m6A CDS       24981863//27773535
chr1:186304481-186304482(-) m6A CDS       24981863//27773535
chr1:186304511-186304512(-) m6A CDS       24981863//27773535
chr1:186304525-186304526(-) Gm CDS       -
chr1:186304532-186304533(-) m6A CDS       24981863//27773535
chr1:186304634-186304635(-) m6A CDS       24981863//27773535//22575960
chr1:186305675-186305676(-) m6A CDS       24981863//27773535
chr1:186305726-186305727(-) m6A CDS       24981863//27773535
chr1:186305760-186305761(-) m6A CDS       24981863//27773535//27371828
chr1:186305784-186305785(-) m6A CDS       24981863//27773535//27371828
chr1:186305807-186305808(-) m6A CDS       24981863//27773535//27371828
chr1:186306188-186306189(-) m6A CDS       24981863//27773535//27371828
chr1:186306216-186306217(-) m6A CDS       24981863//27773535//27371828
chr1:186306256-186306257(-) m6A CDS       24981863//27773535
chr1:186306278-186306279(-) m6A CDS       24981863//27773535
chr1:186307185-186307186(-) m6A CDS       24981863//27773535
chr1:186307199-186307200(-) m6A CDS       24981863//27773535
chr1:186307238-186307239(-) m6A CDS       24981863//27773535
chr1:186307279-186307280(-) m6A CDS       24981863//27773535
chr1:186307292-186307293(-) m6A CDS       24981863//27773535
chr1:186307304-186307305(-) m6A CDS       24981863//27773535//22575960
chr1:186307345-186307346(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186308793-186308794(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186310282-186310283(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310410-186310411(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310416-186310417(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310448-186310449(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310469-186310470(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310475-186310476(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310488-186310489(-) m6A CDS//exon       24981863//28052920//27773535//27371828//22575960
chr1:186310508-186310509(-) m6A CDS//exon       24981863//27773535//27371828//22575960
chr1:186310571-186310572(-) m6A exon//intron       24981863//27773535//27371828
chr1:186310579-186310580(-) m6A exon//intron       24981863//27773535//27371828
chr1:186312496-186312497(-) m6A CDS//exon       24981863
chr1:186312520-186312521(-) m6A CDS//exon       24981863
chr1:186312573-186312574(-) m6A CDS//exon       24981863//22575960
chr1:186313057-186313058(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186313172-186313173(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186313177-186313178(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186313577-186313578(-) m6A CDS       24981863//27773535//22575960
chr1:186314809-186314810(-) m6A CDS       27773535
chr1:186315272-186315273(-) m6A CDS       24981863//27773535
chr1:186315311-186315312(-) m6A CDS       24981863//27773535
chr1:186315317-186315318(-) m6A CDS       24981863//27773535
chr1:186315358-186315359(-) m6A CDS       24981863//27773535//22575960
chr1:186316426-186316427(-) m6A CDS       24981863//27773535//22575960
chr1:186316436-186316437(-) m6A CDS       24981863//27773535//22575960
chr1:186316477-186316478(-) m6A CDS       24981863//28052920//27773535//22575960
chr1:186316497-186316498(-) m6A CDS       24981863//28052920//27773535//22575960
chr1:186316504-186316505(-) m6A CDS       24981863//28052920//27773535//22575960
chr1:186316540-186316541(-) m6A CDS       24981863//28052920//27773535//22575960
chr1:186319363-186319364(-) m6A CDS       24981863//28052920//26404942//27773535//22575960
chr1:186319415-186319416(-) m6A CDS       24981863//26404942//27773535
chr1:186319454-186319455(-) m6A CDS       24981863//26404942//27773535//22575960
chr1:186319480-186319481(-) m6A CDS       24981863//27773535//22575960
chr1:186319496-186319497(-) m6A CDS       24981863//27773535//22575960
chr1:186320491-186320492(-) m6A CDS       24981863//27773535//22575960
chr1:186320536-186320537(-) m6A CDS       24981863//27773535//22575960
chr1:186320542-186320543(-) m6A CDS       24981863//27773535//22575960
chr1:186320569-186320570(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186320574-186320575(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186320580-186320581(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186321115-186321116(-) m6A CDS//exon       27773535
chr1:186321138-186321139(-) m6A CDS//exon       27773535
chr1:186321152-186321153(-) m6A CDS//exon       27773535//27371828
chr1:186322882-186322883(-) m6A CDS//exon       26404942//27773535//27371828//22575960
chr1:186322909-186322910(-) m6A CDS//exon       26404942//27773535//27371828//22575960
chr1:186324606-186324607(-) m6A CDS//exon       24981863
chr1:186324615-186324616(-) m6A CDS//exon       24981863
chr1:186326541-186326542(-) m6A CDS//exon       24981863
chr1:186326548-186326549(-) m6A CDS//exon       24981863
chr1:186326565-186326566(-) m6A CDS//exon       24981863
chr1:186327759-186327760(-) m6A CDS//exon       22575960
chr1:186328942-186328943(-) m6A CDS//exon       24981863//22575960
chr1:186329072-186329073(-) m6A CDS//exon       22575960
chr1:186329080-186329081(-) m6A CDS//exon       22575960
chr1:186329106-186329107(-) m6A CDS//exon       22575960
chr1:186330775-186330776(-) m6A CDS//exon       24981863//27773535
chr1:186330784-186330785(-) m6A CDS//exon       24981863//27773535
chr1:186330805-186330806(-) m6A CDS//exon       24981863//27773535
chr1:186330938-186330939(-) m6A CDS//exon       24981863//26404942//27773535
chr1:186330992-186330993(-) m6A CDS//exon       24981863//26404942//27773535
chr1:186331464-186331465(-) m6A CDS//exon       24981863//27773535
chr1:186331475-186331476(-) m6A CDS//exon       24981863//27773535
chr1:186331494-186331495(-) m6A CDS//exon       24981863//27773535
chr1:186331503-186331504(-) m6A CDS//exon       24981863//27773535
chr1:186332043-186332044(-) m6A CDS//exon       24981863//27773535
chr1:186332051-186332052(-) m6A CDS//exon       24981863//27773535
chr1:186332057-186332058(-) m6A CDS//exon       24981863//27773535
chr1:186332500-186332501(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186332521-186332522(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186332551-186332552(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186337033-186337034(-) m6A CDS//exon       24981863//27773535//22575960
chr1:186337045-186337046(-) m6A CDS//exon       24981863//27773535
chr1:186337056-186337057(-) m6A CDS//exon       24981863//27773535
chr1:186337067-186337068(-) m6A CDS//exon       24981863//27773535
chr1:186337098-186337099(-) m6A CDS//exon       24981863//27773535
chr1:186340137-186340138(-) m6A CDS//exon       24981863//27773535
chr1:186340144-186340145(-) m6A CDS//exon       24981863//27773535
chr1:186342494-186342495(-) m6A CDS//exon       24981863//27773535
chr1:186342532-186342533(-) m6A CDS//exon       24981863//27773535
chr1:186342545-186342546(-) m6A CDS//exon       24981863//27773535
chr1:186344021-186344022(-) Am CDS//exon       -
chr1:186344092-186344093(-) m6A CDS//exon       27773535
chr1:186344116-186344117(-) m6A CDS//exon       27773535//27773536
chr1:186344331-186344332(-) m6A 5'UTR//exon//intron       25456834//24981863//27371828//27773536//22608085
chr1:186344763-186344764(-) m6A 5'UTR       25456834//27371828//27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
TPR
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Exosome Blood     -
Insoluble cytoplasm K562 cells     -
Membrane K562 cells     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -
Ribosome HEK-293 cells     22199352

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: TPR

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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