Detail Information

Basic Information:


  VIRBase ID:  

HHID00017580

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-190a-3p:           FGF12:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-190a-3p FGF12
miRBase
Accession/Entrez ID		 MIMAT0026482 2257
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - DEE47//EIEE47//FGF12B//FHF1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-190a-3p
rs1367478528 chr15:62824008    C/T
rs146591219 chr15:62824027    C/T
rs1311298147 chr15:62824010    A/G
rs771043955 chr15:62824015    T/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR FGF12
chr3:192412763(-) A-I      intronic
chr3:192412789(-) A-I      intronic
chr3:192412797(-) A-I      intronic
chr3:192412803(-) A-I      intronic
chr3:192426041(-) A-I      intronic
chr3:192425962(-) A-I      intronic
chr3:192425491(-) A-I      intronic
chr3:192189891(-) A-I      intronic
chr3:192248741(-) A-I      intronic
chr3:192412760(-) A-I      intronic
chr3:192425489(-) A-I      intronic
chr3:192421693(-) A-I      intronic
chr3:192397311(-) A-I      intronic
chr3:192285786(-) A-I      intronic
chr3:192264778(-) A-I      intronic
chr3:192255801(-) A-I      intronic
chr3:192255796(-) A-I      intronic
chr3:192014128(-) A-I      intronic
chr3:192014169(-) A-I      intronic
chr3:192014177(-) A-I      intronic
chr3:192248736(-) A-I      intronic
chr3:192192638(-) A-I      intronic
chr3:192192622(-) A-I      intronic
chr3:192192566(-) A-I      intronic
chr3:192298591(-) A-I      intronic
chr3:192252421(-) A-I      intronic
chr3:192305345(-) A-I      intronic
chr3:192045665(-) A-I      intronic
chr3:192283710(-) A-I      intronic
chr3:191887008(-) A-I      intronic
chr3:192010850(-) A-I      intronic
chr3:192010844(-) A-I      intronic
chr3:192305574(-) A-I      intronic
chr3:192155353(-) A-I      intronic
chr3:192404874(-) A-I      intronic
chr3:192297428(-) A-I      intronic
chr3:192014195(-) A-I      intronic
chr3:192179667(-) A-I      intronic
chr3:192305494(-) A-I      intronic
chr3:192367461(-) A-I      intronic
chr3:192305488(-) A-I      intronic
chr3:192298661(-) A-I      intronic
chr3:192217616(-) A-I      intronic
chr3:192387209(-) A-I      intronic
chr3:192382433(-) A-I      intronic
chr3:192359476(-) A-I      intronic
chr3:192014178(-) A-I      intronic
chr3:191885827(-) A-I      intronic
chr3:192298660(-) A-I      intronic
chr3:192283828(-) A-I      intronic
chr3:192285840(-) A-I      intronic
chr3:192420377(-) A-I      intronic
chr3:191889734(-) A-I      intronic
chr3:192283788(-) A-I      intronic
chr3:192013768(-) A-I      intronic
chr3:192387362(-) A-I      intronic
chr3:192297410(-) A-I      intronic
chr3:192155397(-) A-I      intronic
chr3:192014208(-) A-I      intronic
chr3:192026320(-) A-I      intronic
chr3:192095954(-) A-I      intronic
chr3:192420378(-) A-I      intronic
chr3:192298655(-) A-I      intronic
chr3:192410251(-) A-I      intronic
chr3:192224364(-) A-I      intronic
chr3:192367465(-) A-I      intronic
chr3:192217436(-) A-I      intronic
chr3:192106047(-) A-I      intronic
chr3:192116443(-) A-I      intronic
chr3:192385312(-) A-I      intronic
chr3:192397130(-) A-I      intronic
chr3:192023788(-) A-I      intronic
chr3:192188220(-) A-I      intronic
chr3:191886990(-) A-I      intronic
chr3:192410373(-) A-I      intronic
chr3:192404707(-) A-I      intronic
chr3:192285801(-) A-I      intronic
chr3:192014209(-) A-I      intronic
chr3:192285790(-) A-I      intronic
chr3:192404756(-) A-I      intronic
chr3:192088280(-) A-I      intronic
chr3:192403004(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED FGF12
chr3:192170015(-) A-I intron -    15342557
chr3:192170031(-) A-I intron -    15342557
chr3:192172689(-) A-I intron -    15342557
chr3:192174693(-) A-I intron -    15342557
chr3:192174818(-) A-I intron -    15342557
chr3:192175678(-) A-I intron -    15342557
chr3:192176024(-) A-I intron -    15342557
chr3:192176039(-) A-I intron -    15342557
chr3:192176415(-) A-I intron -    15342557
chr3:192176491(-) A-I intron -    15342557
chr3:192176492(-) A-I intron -    15342557
chr3:192176551(-) A-I intron -    15342557
chr3:192176861(-) A-I intron -    15342557
chr3:192176871(-) A-I intron -    15342557
chr3:192176883(-) A-I intron -    15342557
chr3:192176919(-) A-I intron -    15342557
chr3:192179667(-) A-G intron -    22484847
chr3:192359196(-) A-T intron -    22484847
chr3:192359209(-) A-C intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase FGF12
chr3:191861413-191861414(-) m6A 3'UTR//exon       27773535
chr3:191861421-191861422(-) m6A 3'UTR//exon       27773535
chr3:191861457-191861458(-) m6A 3'UTR//exon       27773535
chr3:191861478-191861479(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861516-191861517(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861537-191861538(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861623-191861624(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861636-191861637(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861681-191861682(-) m6A 3'UTR//exon       24981863//27773535//22608085
chr3:191861790-191861791(-) m6A 3'UTR//exon       24981863//27773535
chr3:191861844-191861845(-) m6A CDS//exon       24981863//27773535
chr3:191861872-191861873(-) m6A CDS//exon       24981863//27773535
chr3:191861899-191861900(-) m6A CDS//exon       24981863//27773535
chr3:191888256-191888257(-) m6A CDS//exon       24981863//27773535
chr3:191888285-191888286(-) m6A CDS//exon       24981863//27773535
chr3:191888299-191888300(-) m6A CDS//exon       27773535
chr3:191888331-191888332(-) m6A CDS//exon       27773535
chr3:191888398-191888399(-) m6A CDS//exon       27773535
chr3:192126185-192126186(-) m6A 5'UTR//intron       24209618//25456834//24981863//22608085
chr3:192126267-192126268(-) m6A 5'UTR//intron       24209618//25456834//24981863//27773536//22608085
chr3:192126348-192126349(-) m6A 5'UTR//intron       24209618//25456834//24981863//27773536//22608085
chr3:192126448-192126449(-) m6A 5'UTR//intron       24209618//24981863//27773535//22608085
chr3:192126500-192126501(-) m6A 5'UTR//intron       24209618//24981863//27773535
chr3:192126634-192126635(-) m6A 5'UTR//intron       24209618//25456834//24981863//27773535
chr3:192126651-192126652(-) m6A 5'UTR//intron       24209618//25456834//24981863//27773535//22608085
chr3:192126671-192126672(-) m6A 5'UTR//intron       24209618//25456834//24981863//22608085
chr3:192126723-192126724(-) m6A 5'UTR//intron       24209618//25456834//24981863//22608085
chr3:192126767-192126768(-) m6A 5'UTR//intron       24209618//25456834//24981863//22608085
chr3:192126798-192126799(-) m6A 5'UTR//intron       24209618//25456834//24981863
chr3:192390782-192390783(-) m6A exon//intron       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-190a-3p
Exosome Plasma     23663360
Exosome Plasma     24683445
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
FGF12
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleus HeLa-S3 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-190a-3p
Interactor2: FGF12

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence miRDB
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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