Detail Information

Basic Information:


  VIRBase ID:  

HHID00017066

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1307-5p:           NKX2-3:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1307-5p NKX2-3
miRBase
Accession/Entrez ID		 MIMAT0022727 159296
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - CSX3//NK2.3//NKX2.3//NKX2C//NKX4-3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1307-5p
rs1309634229 chr10:103394348    C/CCGGTCGAGATTGGTACA
rs1361155526 chr10:103394342    G/T
rs1368355489 chr10:103394339    CGAGCCGGTCGA/C
rs752308702 chr10:103394349    G/A
rs753442502 chr10:103394342    GCCGGTCGAGGT/GCCGGTCGAGGTCCGGTCGAGGT
rs753442502 chr10:103394342    GCCGGTCGAGGT/G
rs758906629 chr10:103394350    A/AGGTCC
rs762691771 chr10:103394351    G/A
rs766738312 chr10:103394345    G/A
rs766738312 chr10:103394345    G/C
rs909057468 chr10:103394348    C/T
rs1485833698 chr10:103394358    T/C
rs745681690 chr10:103394354    C/T
rs750389441 chr10:103394360    G/A
rs750389441 chr10:103394360    G/C
rs751122680 chr10:103394356    G/A
rs757138030 chr10:103394359    C/G
rs757138030 chr10:103394359    C/T
rs763490878 chr10:103394355    C/G
rs763490878 chr10:103394355    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase NKX2-3
chr10:101292871-101292872(+) m6A 5'UTR       22608085
chr10:101292934-101292935(+) m6A CDS       24981863//22608085
chr10:101292991-101292992(+) m6A CDS       24981863//22608085
chr10:101293108-101293109(+) m6A CDS       24981863
chr10:101295642-101295643(+) m6A 3'UTR       22608085
chr10:101295681-101295682(+) m6A 3'UTR       24981863//22608085
chr10:101295753-101295754(+) m6A 3'UTR       22608085
chr10:101295767-101295768(+) m6A 3'UTR       22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1307-5p
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Blood|B lymphoblastoid cells|Chronic lymphocytic leukemia cells|Endothelial cells|Kidney tissue|Lymphoma tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
NKX2-3
Exosome Blood     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1307-5p
Interactor2: NKX2-3

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...