Detail Information

Basic Information:


  VIRBase ID:  

HHID00017065

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1307-5p:           RBM33:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1307-5p RBM33
miRBase
Accession/Entrez ID		 MIMAT0022727 155435
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - PRR8

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1307-5p
rs1309634229 chr10:103394348    C/CCGGTCGAGATTGGTACA
rs1361155526 chr10:103394342    G/T
rs1368355489 chr10:103394339    CGAGCCGGTCGA/C
rs752308702 chr10:103394349    G/A
rs753442502 chr10:103394342    GCCGGTCGAGGT/GCCGGTCGAGGTCCGGTCGAGGT
rs753442502 chr10:103394342    GCCGGTCGAGGT/G
rs758906629 chr10:103394350    A/AGGTCC
rs762691771 chr10:103394351    G/A
rs766738312 chr10:103394345    G/A
rs766738312 chr10:103394345    G/C
rs909057468 chr10:103394348    C/T
rs1485833698 chr10:103394358    T/C
rs745681690 chr10:103394354    C/T
rs750389441 chr10:103394360    G/A
rs750389441 chr10:103394360    G/C
rs751122680 chr10:103394356    G/A
rs757138030 chr10:103394359    C/G
rs757138030 chr10:103394359    C/T
rs763490878 chr10:103394355    C/G
rs763490878 chr10:103394355    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR RBM33
chr7:155465371(+) A-I      intronic
chr7:155465351(+) A-I      intronic
chr7:155448524(+) A-I      intronic
chr7:155522356(+) A-I      intronic
chr7:155520597(+) A-I      intronic
chr7:155520572(+) A-I      intronic
chr7:155520559(+) A-I      intronic
chr7:155520498(+) A-I      intronic
chr7:155484758(+) A-I      intronic
chr7:155484665(+) A-I      intronic
chr7:155484660(+) A-I      intronic
chr7:155484594(+) A-I      intronic
chr7:155484585(+) A-I      intronic
chr7:155484566(+) A-I      intronic
chr7:155467934(+) A-I      intronic
chr7:155467903(+) A-I      intronic
chr7:155467843(+) A-I      intronic
chr7:155474719(+) A-I      intronic
chr7:155566139(+) A-I      intronic
chr7:155494521(+) A-I      intronic
chr7:155528213(+) A-I      intronic
chr7:155566141(+) A-I      intronic
chr7:155474744(+) A-I      intronic
chr7:155522394(+) A-I      intronic
chr7:155566168(+) A-I      intronic
chr7:155522368(+) A-I      intronic
chr7:155520653(+) A-I      intronic
chr7:155474754(+) A-I      intronic
chr7:155494511(+) A-I      intronic
chr7:155499067(+) A-I      intronic
chr7:155474798(+) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED RBM33
chr7:155444214(+) T-C intron -    22484847
chr7:155474798(+) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase RBM33
chr7:155437425-155437426(+) m6A 5'UTR       24981863
chr7:155437505-155437506(+) m6A 5'UTR       -
chr7:155457937-155457938(+) m6A CDS       24981863
chr7:155457943-155457944(+) m6A CDS       24981863
chr7:155465563-155465564(+) m6A CDS       24981863
chr7:155473340-155473341(+) m6A CDS       24981863//27773535//22608085
chr7:155473373-155473374(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473391-155473392(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473397-155473398(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473412-155473413(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473468-155473469(+) m1A CDS       26863196
chr7:155473472-155473473(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473507-155473508(+) m6A CDS       24284625//24981863//27773535//22608085
chr7:155473513-155473514(+) Tm CDS       -
chr7:155473567-155473568(+) m6A CDS       24981863//27773535//22608085
chr7:155473583-155473584(+) m6A CDS       24981863//27773535//22608085
chr7:155477681-155477682(+) m6A CDS//intron       24981863
chr7:155493478-155493479(+) m6A CDS       24981863//27773535
chr7:155493486-155493487(+) m6A CDS       24981863//27773535
chr7:155493497-155493498(+) m6A CDS       24981863//27773535
chr7:155493562-155493563(+) m6A CDS       24981863//27773535
chr7:155493580-155493581(+) m6A CDS       24981863//27773535
chr7:155493620-155493621(+) m6A CDS       24981863//27773535
chr7:155493631-155493632(+) m6A CDS       24981863//27773535
chr7:155499614-155499615(+) m6A CDS//exon       24981863
chr7:155499682-155499683(+) m6A CDS//exon       24981863
chr7:155499721-155499722(+) m6A CDS//exon       24981863
chr7:155499728-155499729(+) m6A CDS//exon       24981863
chr7:155500047-155500048(+) m6A 3'UTR//intron       -
chr7:155504046-155504047(+) m6A 3'UTR//CDS//exon       24284625
chr7:155504098-155504099(+) m6A 3'UTR//CDS//exon       24284625
chr7:155511109-155511110(+) m6A 3'UTR//CDS//exon       24284625
chr7:155511121-155511122(+) m6A 3'UTR//CDS//exon       24284625
chr7:155530255-155530256(+) m6A 3'UTR//CDS       24284625
chr7:155530302-155530303(+) m6A 3'UTR//CDS       -
chr7:155530338-155530339(+) m6A 3'UTR//CDS       24284625//24981863
chr7:155530763-155530764(+) m6A 3'UTR//CDS       24284625//24981863
chr7:155530793-155530794(+) m6A 3'UTR//CDS       24284625//24981863
chr7:155530889-155530890(+) m6A 3'UTR//CDS       24284625//24981863
chr7:155530910-155530911(+) m6A 3'UTR//CDS       24284625
chr7:155531033-155531034(+) m6A 3'UTR//CDS       24284625
chr7:155531057-155531058(+) m6A 3'UTR//CDS       24284625
chr7:155531115-155531116(+) m6A 3'UTR//intron       24284625
chr7:155532377-155532378(+) m6A 3'UTR//intron       -
chr7:155532657-155532658(+) m6A 3'UTR//CDS       24284625//24209618
chr7:155534576-155534577(+) m6A 3'UTR//CDS       -
chr7:155534667-155534668(+) m6A 3'UTR//CDS       -
chr7:155534788-155534789(+) m6A 3'UTR//CDS       24284625//27773535//22608085
chr7:155534794-155534795(+) m6A 3'UTR//CDS       24284625//27773535//22608085
chr7:155537675-155537676(+) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085
chr7:155537704-155537705(+) m6A 3'UTR//CDS       24284625//24981863//27773535//22608085
chr7:155537734-155537735(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22575960//22608085
chr7:155537794-155537795(+) m6A 3'UTR//CDS       24284625//25456834//24981863//27773535//22575960//22608085
chr7:155537917-155537918(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr7:155537931-155537932(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr7:155537949-155537950(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//22575960//22608085
chr7:155537984-155537985(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538028-155538029(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538049-155538050(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538058-155538059(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538062-155538063(+) m6A 3'UTR//CDS       24981863
chr7:155538068-155538069(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538086-155538087(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538118-155538119(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085
chr7:155538152-155538153(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr7:155538189-155538190(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr7:155538212-155538213(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr7:155538227-155538228(+) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27371828//22575960//22608085
chr7:155539317-155539318(+) m6A 5'UTR//intron       25456834
chr7:155556576-155556577(+) m6A 5'UTR//CDS       24284625//24209618//25456834//22608085
chr7:155559224-155559225(+) m6A CDS       24284625
chr7:155559233-155559234(+) m6A CDS       24284625
chr7:155559339-155559340(+) m6A CDS       24284625
chr7:155559584-155559585(+) m6A 3'UTR//intron       -
chr7:155567812-155567813(+) m6A 3'UTR//CDS       24284625//25456834//24981863//22575960//22608085
chr7:155567905-155567906(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr7:155567914-155567915(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr7:155567971-155567972(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr7:155568023-155568024(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr7:155568082-155568083(+) m6A 3'UTR       24284625//24209618//24981863//22608085
chr7:155570132-155570133(+) m6A 3'UTR       27773535
chr7:155570170-155570171(+) m6A 3'UTR       24981863//27773535
chr7:155570260-155570261(+) m6A 3'UTR       24981863
chr7:155571340-155571341(+) m6A 3'UTR       -
chr7:155572920-155572921(+) Y 3'UTR       26075521

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1307-5p
Exosome Plasma     23663360
Exosome Colon cancer cell line (LIM1863)     25330373
Exosome Blood|B lymphoblastoid cells|Chronic lymphocytic leukemia cells|Endothelial cells|Kidney tissue|Lymphoma tissue     -
Microvesicle Serum     24797360
Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
RBM33
Chromatin K562 cells     -
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol HCC cell line (HepG2)|K562 cells     -
Exosome Blood     -
Membrane HCC cell line (HepG2)     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600
Nucleus HCC cell line (HepG2)|HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1307-5p
Interactor2: RBM33

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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