Basic Information:

  VIRBase ID:  

HHID00016997

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1307-5p:  MIMAT0022727          SOX12:  NM_006943     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-1307-5p	SOX12
miRBase Accession/Entrez ID	MIMAT0022727	6666
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	SOX22

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-1307-5p	rs1309634229 chr10:103394348    C/CCGGTCGAGATTGGTACA rs1361155526 chr10:103394342    G/T rs1368355489 chr10:103394339    CGAGCCGGTCGA/C rs752308702 chr10:103394349    G/A rs753442502 chr10:103394342    GCCGGTCGAGGT/GCCGGTCGAGGTCCGGTCGAGGT rs753442502 chr10:103394342    GCCGGTCGAGGT/G rs758906629 chr10:103394350    A/AGGTCC rs762691771 chr10:103394351    G/A rs766738312 chr10:103394345    G/A rs766738312 chr10:103394345    G/C rs909057468 chr10:103394348    C/T rs1485833698 chr10:103394358    T/C rs745681690 chr10:103394354    C/T rs750389441 chr10:103394360    G/A rs750389441 chr10:103394360    G/C rs751122680 chr10:103394356    G/A rs757138030 chr10:103394359    C/G rs757138030 chr10:103394359    C/T rs763490878 chr10:103394355    C/G rs763490878 chr10:103394355    C/T

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SOX12	chr20:306310-306311(+) m6A 5'UTR       24284625//24209618//24981863 chr20:306377-306378(+) m6A 5'UTR       24284625//24209618//24981863 chr20:306624-306625(+) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr20:306670-306671(+) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr20:306746-306747(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:306815-306816(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:306884-306885(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307108-307109(+) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr20:307161-307162(+) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085 chr20:307364-307365(+) m6A CDS       24284625//24209618//25456834//24981863//27773536//22575960//22608085 chr20:307391-307392(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307433-307434(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307472-307473(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307496-307497(+) m6A CDS       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307548-307549(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//22575960//22608085 chr20:307664-307665(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:307683-307684(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:307808-307809(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085 chr20:307857-307858(+) m6A 3'UTR       24284625//24209618//25456834//24981863 chr20:308249-308250(+) m6A 3'UTR       24284625 chr20:308420-308421(+) m6A 3'UTR       24284625//24981863 chr20:308433-308434(+) m6A 3'UTR       24284625//24981863 chr20:308440-308441(+) m6A 3'UTR       24284625//24981863//22575960//22608085 chr20:308469-308470(+) m6A 3'UTR       24284625//25456834//24981863//22575960//22608085 chr20:308621-308622(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:308651-308652(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:308686-308687(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:308700-308701(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:308718-308719(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:308739-308740(+) m6A 3'UTR       24284625//24209618//25456834//24981863//26404942//27773535//22575960//22608085 chr20:309023-309024(+) m6A 3'UTR       24284625//24209618 chr20:309047-309048(+) m6A 3'UTR       24284625//24209618 chr20:309188-309189(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr20:309207-309208(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr20:309266-309267(+) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085 chr20:309326-309327(+) m6A 3'UTR       24284625//24981863//27773535//22608085 chr20:309348-309349(+) m6A 3'UTR       24284625//24981863//22608085 chr20:309422-309423(+) m6A 3'UTR       24981863 chr20:309769-309770(+) m6A 3'UTR       -

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-1307-5p	Exosome Plasma     23663360 Exosome Colon cancer cell line (LIM1863)     25330373 Exosome Blood|B lymphoblastoid cells|Chronic lymphocytic leukemia cells|Endothelial cells|Kidney tissue|Lymphoma tissue     - Microvesicle Serum     24797360 Microvesicle Colon cancer cell line (LIM1863)|Fibroblasts|Mesenchymal stem cells|Urine     -
	SOX12	Chromatin K562 cells     - Cytosol Human myelogenous leukemia cell line (K-562)     21613539 Cytosol K562 cells     - Exosome Blood     - Nucleolus K562 cells     - Nucleus HCC cell line (HepG2)     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-1307-5p
Interactor2: SOX12

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).