Basic Information:

  VIRBase ID:  

HHID00016132

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-23c:  MIMAT0018000          SFT2D3:  NM_032740     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-23c	SFT2D3
miRBase Accession/Entrez ID	MIMAT0018000	84826
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	-

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-23c	rs1395024960 chrX:20017114    C/A rs1449990033 chrX:20017107    T/C rs898099862 chrX:20017112    G/A

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	SFT2D3	chr2:128459109-128459110(+) m6A CDS       25456834//24981863//27371828 chr2:128459211-128459212(+) m6A CDS       24209618 chr2:128459752-128459753(+) m6A 3'UTR       24209618//25456834//24981863//22608085 chr2:128459802-128459803(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:128459823-128459824(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:128459957-128459958(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:128459977-128459978(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:128459996-128459997(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085 chr2:128460192-128460193(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr2:128460245-128460246(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr2:128460265-128460266(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr2:128460386-128460387(+) m6A 3'UTR       24284625//24209618//24981863//22608085 chr2:128460515-128460516(+) m6A 3'UTR       24981863//22608085 chr2:128460569-128460570(+) m6A 3'UTR       24981863//22608085 chr2:128461158-128461159(+) m6A 3'UTR       24981863 chr2:128461183-128461184(+) m6A 3'UTR       24981863

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-23c	Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Fibroblasts|Mesenchymal stem cells     -
	SFT2D3	Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539 Exosome Blood     - Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-23c
Interactor2: SFT2D3

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).