Detail Information

Basic Information:


  VIRBase ID:  

HHID00015309

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p LA16c-431H6.6
miRBase
Accession/Entrez ID		 MIMAT0009199 LA16c-431H6.6
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase LA16c-431H6.6
chr16:1703051-1703052(+) m6A 3'UTR       -
chr16:1703105-1703106(+) m6A 3'UTR       -
chr16:1703144-1703145(+) m6A 3'UTR       24284625
chr16:1704734-1704735(+) Tm intron       -
chr16:1705296-1705297(+) Gm 3'UTR       -
chr16:1705883-1705884(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr16:1705908-1705909(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr16:1705965-1705966(+) m6A intron       24284625//25456834//24981863//22608085
chr16:1706310-1706311(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706333-1706334(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706352-1706353(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706406-1706407(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706433-1706434(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706466-1706467(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706499-1706500(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1706649-1706650(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr16:1706719-1706720(+) m6A 3'UTR       24284625//25456834//24981863//22608085
chr16:1706793-1706794(+) m6A 3'UTR       24284625//25456834
chr16:1706801-1706802(+) m6A 3'UTR       24284625//25456834
chr16:1706898-1706899(+) m6A 3'UTR       24284625//24981863
chr16:1709899-1709900(+) m6A 3'UTR       24284625
chr16:1710004-1710005(+) m6A 3'UTR       24284625
chr16:1710030-1710031(+) m6A 3'UTR       24284625
chr16:1712499-1712500(+) m6A 3'UTR       24284625
chr16:1712509-1712510(+) m6A 3'UTR       -
chr16:1719029-1719030(+) m6A 3'UTR       24284625
chr16:1724127-1724128(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724150-1724151(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724221-1724222(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724360-1724361(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22608085
chr16:1724386-1724387(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724487-1724488(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724520-1724521(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724535-1724536(+) m6A 3'UTR       24284625//24209618//25456834//24981863//22575960//22608085
chr16:1724726-1724727(+) m6A 3'UTR       24209618//24981863
chr16:1724738-1724739(+) m6A 3'UTR       24209618//24981863
chr16:1724789-1724790(+) m6A 3'UTR       24209618
chr16:1724805-1724806(+) m6A 3'UTR       -
chr16:1724924-1724925(+) m6A 3'UTR       -
chr16:1724945-1724946(+) m6A 3'UTR       -
chr16:1725235-1725236(+) m6A 3'UTR       24284625
chr16:1725435-1725436(+) m6A 3'UTR       -
chr16:1725639-1725640(+) m6A 3'UTR       24981863
chr16:1725685-1725686(+) m6A 3'UTR       -
chr16:1725692-1725693(+) m6A 3'UTR       -
chr16:1725771-1725772(+) m6A intron       24981863
chr16:1725795-1725796(+) m6A intron       24981863
chr16:1725805-1725806(+) m6A intron       24981863
chr16:1725828-1725829(+) m6A intron       24981863
chr16:1730409-1730410(+) m6A intron       24981863
chr16:1730421-1730422(+) m6A intron       24981863
chr16:1735541-1735542(+) m6A 3'UTR       -
chr16:1735553-1735554(+) m6A 3'UTR       -
chr16:1735561-1735562(+) m6A 3'UTR       -
chr16:1735575-1735576(+) m6A 3'UTR       -

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: LA16c-431H6.6

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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