Detail Information

Basic Information:


  VIRBase ID:  

HHID00015300

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p CTC-360G5.8
miRBase
Accession/Entrez ID		 MIMAT0009199 CTC-360G5.8
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase CTC-360G5.8
chr19:39406109-39406110(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr19:39406175-39406176(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr19:39406184-39406185(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960//22608085
chr19:39406191-39406192(-) m6A 3'UTR       24284625//25456834//24981863//27773535//22575960
chr19:39406242-39406243(-) m6A 3'UTR       24284625//27773535
chr19:39406708-39406709(-) m6A CDS       27773535
chr19:39406929-39406930(-) m6A CDS       27773535
chr19:39408712-39408713(-) m6A intron       27773535
chr19:39408745-39408746(-) m6A CDS       27773535
chr19:39408766-39408767(-) m6A CDS       27773535
chr19:39409082-39409083(-) m6A CDS       27773535
chr19:39412180-39412181(-) m6A CDS       27773535
chr19:39412305-39412306(-) m6A CDS       27371828
chr19:39412474-39412475(-) m6A intron       -
chr19:39412896-39412897(-) m6A CDS       24209618//27371828//27773536
chr19:39412902-39412903(-) m6A CDS       24209618//27371828//27773536
chr19:39426087-39426088(-) m6A intron       24981863
chr19:39426117-39426118(-) m6A intron       24981863
chr19:39426170-39426171(-) m6A intron       24981863//27773535
chr19:39426257-39426258(-) m6A intron       24981863//27773535
chr19:39426268-39426269(-) m6A intron       24981863//27773535
chr19:39426280-39426281(-) m6A intron       24981863//27773535
chr19:39426304-39426305(-) m6A intron       24981863//27773535
chr19:39426315-39426316(-) m6A intron       24981863//27773535
chr19:39426327-39426328(-) m6A intron       24981863//27773535
chr19:39426472-39426473(-) m6A intron       24981863
chr19:39426510-39426511(-) m6A intron       24981863
chr19:39426535-39426536(-) m6A intron       24981863
chr19:39426549-39426550(-) m6A intron       24981863
chr19:39426581-39426582(-) m6A intron       24981863
chr19:39426612-39426613(-) m6A intron       24981863
chr19:39426683-39426684(-) m6A intron       24981863
chr19:39426701-39426702(-) m6A intron       24981863
chr19:39426759-39426760(-) m6A intron       24981863
chr19:39426944-39426945(-) m6A intron       24981863
chr19:39426994-39426995(-) m6A intron       24981863
chr19:39427004-39427005(-) m6A intron       24981863
chr19:39427016-39427017(-) m6A intron       24981863
chr19:39427155-39427156(-) m6A intron       24981863//27773535//22608085
chr19:39427247-39427248(-) m6A intron       24981863//27773535
chr19:39427263-39427264(-) m6A intron       24981863//27773535
chr19:39427298-39427299(-) m6A intron       24981863
chr19:39427318-39427319(-) m6A intron       24981863
chr19:39427348-39427349(-) m6A intron       24981863
chr19:39427364-39427365(-) m6A intron       24981863//27773535
chr19:39427397-39427398(-) m6A intron       24981863//27773535
chr19:39427404-39427405(-) m6A intron       24981863//27773535
chr19:39427448-39427449(-) m6A intron       27773535
chr19:39427457-39427458(-) m6A intron       27773535
chr19:39427789-39427790(-) m6A intron       27773535
chr19:39427822-39427823(-) m6A intron       27773535
chr19:39432220-39432221(-) m6A intron       27773535
chr19:39432279-39432280(-) m6A intron       27773535
chr19:39432286-39432287(-) m6A intron       27773535
chr19:39432307-39432308(-) m6A intron       27773535
chr19:39432332-39432333(-) m6A intron       27773535
chr19:39432419-39432420(-) m6A intron       24284625//25456834//24981863
chr19:39432430-39432431(-) m6A intron       24284625//25456834//24981863
chr19:39432442-39432443(-) m6A intron       24284625//25456834//24981863
chr19:39432466-39432467(-) m6A intron       24284625//24209618//25456834//24981863//27773535
chr19:39432511-39432512(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432584-39432585(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432639-39432640(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432650-39432651(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432663-39432664(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432715-39432716(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432768-39432769(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432861-39432862(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432898-39432899(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432930-39432931(-) m6A intron       24284625//24209618//25456834//24981863//26404942//27773535//22608085
chr19:39432996-39432997(-) m6A intron       24284625//24209618//25456834//24981863//27773535//22608085
chr19:39433094-39433095(-) m6A intron       24284625//24209618//24981863//27773535
chr19:39433117-39433118(-) m6A intron       24284625//24209618//24981863//27773535
chr19:39433213-39433214(-) m6A intron       24284625//24209618//24981863//27773535
chr19:39433239-39433240(-) m6A intron       24284625//24209618//24981863//27773535
chr19:39435399-39435400(-) m6A intron       27773535
chr19:39435418-39435419(-) m6A intron       27773535
chr19:39435597-39435598(-) m6A intron       24284625//24209618//27773535//22608085
chr19:39435628-39435629(-) m6A CDS       24284625//24209618//27773535//22608085
chr19:39435908-39435909(-) m6A intron       -
chr19:39435949-39435950(-) m6A intron       -
chr19:39435990-39435991(-) m6A intron       27773536
chr19:39436062-39436063(-) m6A intron       25456834//27773536
chr19:39436072-39436073(-) m6A intron       25456834//27773536
chr19:39436086-39436087(-) m6A intron       24284625//25456834//27773536
chr19:39436095-39436096(-) m6A intron       24284625//25456834//27773536
chr19:39436136-39436137(-) m6A intron       24284625//25456834//27773536
chr19:39436159-39436160(-) m6A intron       24284625//27773536
chr19:39436200-39436201(-) m6A intron       24284625//27773536
chr19:39436214-39436215(-) m6A intron       24284625//27773536
chr19:39436223-39436224(-) m6A intron       24284625//27773536
chr19:39436262-39436263(-) m6A intron       24284625//27773536
chr19:39436285-39436286(-) m6A intron       24284625//27773536
chr19:39436326-39436327(-) m6A intron       24284625//27773536
chr19:39436349-39436350(-) m6A intron       24284625//27773536
chr19:39436422-39436423(-) m6A intron       24284625
chr19:39436431-39436432(-) m6A intron       24284625
chr19:39436470-39436471(-) m6A intron       24284625//27773535
chr19:39436493-39436494(-) m6A intron       24284625//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: CTC-360G5.8

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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