Detail Information

Basic Information:


  VIRBase ID:  

HHID00015016

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           PIGM:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p PIGM
miRBase
Accession/Entrez ID		 MIMAT0009199 93183
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GPI-MT-I

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR PIGM
chr1:159999689(-) A-I      3'UTR
chr1:159999263(-) A-I      3'UTR
chr1:159999419(-) A-I      3'UTR
chr1:159999790(-) A-I      3'UTR
chr1:159999688(-) A-I      3'UTR
chr1:159999328(-) A-I      3'UTR
chr1:159999654(-) A-I      3'UTR
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED PIGM
chr1:159999790(-) A-I intron -    21960545

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase PIGM
chr1:159997908-159997909(-) Y 3'UTR       26075521
chr1:159999282-159999283(-) m6A 3'UTR       24981863
chr1:159999379-159999380(-) m6A 3'UTR       24981863//22608085
chr1:159999402-159999403(-) m6A 3'UTR       24981863//27773535//22608085
chr1:159999448-159999449(-) m6A 3'UTR       24981863//27773535//22608085
chr1:159999489-159999490(-) m6A 3'UTR       24981863//27773535//22608085
chr1:159999559-159999560(-) m6A 3'UTR       27773535
chr1:159999946-159999947(-) m6A 3'UTR       24981863//27773535//22608085
chr1:159999977-159999978(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr1:159999993-159999994(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr1:160000042-160000043(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr1:160000057-160000058(-) m6A 3'UTR       24284625//24981863//27773535//22608085
chr1:160000095-160000096(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160000130-160000131(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160000172-160000173(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr1:160000185-160000186(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr1:160000204-160000205(-) m6A 3'UTR       24284625//24209618//24981863//27773535//22608085
chr1:160000287-160000288(-) m6A CDS       24209618//24981863//27773535//22608085
chr1:160000378-160000379(-) m6A CDS       -
chr1:160000594-160000595(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160000764-160000765(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160000824-160000825(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160001037-160001038(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160001089-160001090(-) m6A CDS       24284625//24209618//24981863//27773535//22575960//22608085
chr1:160001383-160001384(-) m6A CDS       24284625//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr1:160001405-160001406(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:160001410-160001411(-) m6A CDS       24284625//25456834//24981863//27371828//27773536//22575960//22608085
chr1:160001491-160001492(-) m6A CDS       24284625//24209618//25456834//24981863//27371828//27773536//22575960//22608085
chr1:160001598-160001599(-) m6A 5'UTR       24284625//24209618//24981863//27371828//22608085
chr1:160001705-160001706(-) m6A 5'UTR       24284625//24981863//22608085
chr1:160001722-160001723(-) m6A 5'UTR       24284625//24981863//22608085
chr1:160001770-160001771(-) m6A 5'UTR       24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
PIGM
Endoplasmic reticulum Human myelogenous leukemia cell line (K-562)     21613539
Exosome Blood     -
Nucleolus K562 cells     -
Ribosome HEK-293 cells     22199352
Ribosome Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: PIGM

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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