Detail Information

Basic Information:


  VIRBase ID:  

HHID00014766

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           KBTBD4:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p KBTBD4
miRBase
Accession/Entrez ID		 MIMAT0009199 55709
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - BKLHD4//HSPC252

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase KBTBD4
chr11:47594202-47594203(-) m6A 3'UTR       27773535
chr11:47594596-47594597(-) m6A CDS       24284625//24209618
chr11:47594692-47594693(-) m6A CDS       24284625//24209618//24981863//27773535//22608085
chr11:47594722-47594723(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//22608085
chr11:47594819-47594820(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:47594853-47594854(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:47594866-47594867(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:47594957-47594958(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:47594963-47594964(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr11:47595023-47595024(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr11:47595088-47595089(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr11:47595181-47595182(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr11:47595226-47595227(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr11:47599114-47599115(-) m6A 3'UTR//CDS       24284625//22608085
chr11:47599183-47599184(-) m6A 3'UTR//CDS       24284625//24981863//27371828//22608085
chr11:47599224-47599225(-) m6A 3'UTR//CDS       24284625//24981863//22608085
chr11:47599232-47599233(-) m6A 3'UTR//CDS       24284625//24981863//22608085
chr11:47599443-47599444(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr11:47599486-47599487(-) Am 3'UTR//CDS       -
chr11:47599498-47599499(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr11:47599510-47599511(-) m6A 3'UTR//CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr11:47599579-47599580(-) m6A 5'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr11:47599628-47599629(-) m6A 5'UTR//CDS//intron       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr11:47599644-47599645(-) m6A 5'UTR//intron       24209618//25456834//24981863//27371828//27773536//22608085
chr11:47599687-47599688(-) m6A 5'UTR//intron       24209618//25456834//24981863//22608085
chr11:47599703-47599704(-) m6A 5'UTR//intron       22608085
chr11:47599723-47599724(-) m6A 5'UTR//intron       22608085
chr11:47600086-47600087(-) m6A 5'UTR//intron       25456834
chr11:47600173-47600174(-) m6A 5'UTR//CDS//intron       25456834//24981863
chr11:47600224-47600225(-) m6A 5'UTR//intron       25456834
chr11:47600387-47600388(-) m6A 5'UTR//intron       24981863
chr11:47600470-47600471(-) m6A 5'UTR//intron       24209618//24981863

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
KBTBD4
Exosome Blood     -
Nucleus K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: KBTBD4

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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