Basic Information:

  VIRBase ID:  

HHID00014569

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:  MIMAT0009199          ZFR2:  NR_027149     

      *It may take a few minutes to display results.

Interactor Information:

	Interactor1	Interactor2
Symbol	hsa-miR-365a-5p	ZFR2
miRBase Accession/Entrez ID	MIMAT0009199	23217
Organism	Homo sapiens	Homo sapiens
Category	miRNA	mRNA
Alias	-	KIAA1086

ncRNA SNP information:

Resource	Symbol	SNP ID	SNP Position	Ref/Alt
miRNASNP-v3	hsa-miR-365a-5p	rs1166908611 chr16:14309308    T/C rs1368596991 chr16:14309314    G/A rs1380926089 chr16:14309318    A/G rs1396179427 chr16:14309310    G/C rs1428928383 chr16:14309320    G/A rs773834113 chr16:14309301    G/C

RNA Editing:

Resource	Symbol	Editing Position	Change	Genetic Region
RADAR	ZFR2	chr19:3854025(-) A-I      intronic chr19:3865373(-) A-I      intronic chr19:3865383(-) A-I      intronic chr19:3865378(-) A-I      intronic chr19:3865400(-) A-I      intronic chr19:3865363(-) A-I      intronic chr19:3856857(-) A-I      intronic chr19:3857635(-) A-I      intronic chr19:3861562(-) A-I      intronic chr19:3863514(-) A-I      intronic chr19:3860173(-) A-I      intronic chr19:3812074(-) A-I      intronic chr19:3812079(-) A-I      intronic chr19:3812080(-) A-I      intronic chr19:3829715(-) A-I      intronic chr19:3812112(-) A-I      intronic chr19:3812894(-) A-I      intronic chr19:3832812(-) A-I      intronic chr19:3832815(-) A-I      intronic chr19:3832816(-) A-I      intronic chr19:3832832(-) A-I      intronic chr19:3855161(-) A-I      intronic chr19:3855170(-) A-I      intronic chr19:3860121(-) A-I      intronic chr19:3841756(-) A-I      intronic chr19:3843417(-) A-I      intronic chr19:3843416(-) A-I      intronic chr19:3842139(-) A-I      intronic chr19:3841767(-) A-I      intronic chr19:3841601(-) A-I      intronic chr19:3841648(-) A-I      intronic chr19:3813052(-) A-I      intronic chr19:3812310(-) A-I      intronic chr19:3841649(-) A-I      intronic chr19:3865440(-) A-I      intronic chr19:3865420(-) A-I      intronic chr19:3811521(-) A-I      intronic chr19:3860167(-) A-I      intronic chr19:3819837(-) A-I      intronic chr19:3811999(-) A-I      intronic chr19:3811538(-) A-I      intronic chr19:3811529(-) A-I      intronic chr19:3811515(-) A-I      intronic chr19:3811510(-) A-I      intronic chr19:3824047(-) A-I      intronic chr19:3819689(-) A-I      intronic chr19:3829633(-) A-I      intronic chr19:3833407(-) A-I      intronic chr19:3833452(-) A-I      intronic chr19:3840640(-) A-I      intronic chr19:3840794(-) A-I      intronic chr19:3841600(-) A-I      intronic chr19:3805531(-) A-I      3'UTR chr19:3822387(-) A-I      intronic chr19:3861481(-) A-I      intronic chr19:3833057(-) A-I      intronic chr19:3861422(-) A-I      intronic chr19:3857485(-) A-I      intronic chr19:3842826(-) A-I      intronic chr19:3864989(-) A-I      intronic chr19:3836411(-) A-I      intronic chr19:3830311(-) A-I      intronic chr19:3830086(-) A-I      intronic chr19:3862522(-) A-I      intronic chr19:3857121(-) A-I      intronic chr19:3829682(-) A-I      intronic chr19:3809776(-) A-I      intronic chr19:3829127(-) A-I      intronic chr19:3854339(-) A-I      intronic chr19:3830295(-) A-I      intronic chr19:3829540(-) A-I      intronic chr19:3842285(-) A-I      intronic chr19:3860059(-) A-I      intronic chr19:3818464(-) A-I      intronic chr19:3832513(-) A-I      intronic chr19:3812930(-) A-I      intronic chr19:3861861(-) A-I      intronic chr19:3864874(-) A-I      intronic chr19:3857599(-) A-I      intronic chr19:3830327(-) A-I      intronic chr19:3830202(-) A-I      intronic chr19:3812327(-) A-I      intronic chr19:3829546(-) A-I      intronic chr19:3822602(-) A-I      intronic chr19:3845731(-) A-I      intronic chr19:3854315(-) A-I      intronic chr19:3836375(-) A-I      intronic chr19:3822363(-) A-I      intronic chr19:3854291(-) A-I      intronic chr19:3829139(-) A-I      intronic chr19:3812009(-) A-I      intronic chr19:3829027(-) A-I      intronic chr19:3829579(-) A-I      intronic chr19:3830387(-) A-I      intronic chr19:3809860(-) A-I      intronic chr19:3811520(-) A-I      intronic chr19:3833000(-) A-I      intronic chr19:3812885(-) A-I      intronic chr19:3854132(-) A-I      intronic chr19:3832366(-) A-I      intronic chr19:3830132(-) A-I      intronic chr19:3829687(-) A-I      intronic chr19:3829761(-) A-I      intronic chr19:3830274(-) A-I      intronic chr19:3832417(-) A-I      intronic chr19:3861667(-) A-I      intronic chr19:3865450(-) A-I      intronic chr19:3864243(-) A-I      intronic chr19:3842149(-) A-I      intronic chr19:3822521(-) A-I      intronic chr19:3812995(-) A-I      intronic chr19:3855150(-) A-I      intronic chr19:3836369(-) A-I      intronic chr19:3854847(-) A-I      intronic chr19:3824077(-) A-I      intronic chr19:3862569(-) A-I      intronic chr19:3858704(-) A-I      intronic chr19:3854830(-) A-I      intronic chr19:3832749(-) A-I      intronic chr19:3822632(-) A-I      intronic chr19:3856964(-) A-I      intronic chr19:3812014(-) A-I      intronic chr19:3833426(-) A-I      intronic chr19:3828271(-) A-I      intronic chr19:3846157(-) A-I      intronic chr19:3864294(-) A-I      intronic chr19:3861541(-) A-I      intronic chr19:3829056(-) A-I      intronic chr19:3812155(-) A-I      intronic chr19:3865445(-) A-I      intronic chr19:3832458(-) A-I      intronic chr19:3822715(-) A-I      intronic chr19:3854338(-) A-I      intronic chr19:3829071(-) A-I      intronic chr19:3826629(-) A-I      intronic chr19:3854896(-) A-I      intronic chr19:3815696(-) A-I      intronic chr19:3829784(-) A-I      intronic chr19:3804950(-) A-I      3'UTR chr19:3822439(-) A-I      intronic chr19:3854124(-) A-I      intronic chr19:3804975(-) A-I      3'UTR chr19:3832355(-) A-I      intronic chr19:3854014(-) A-I      intronic chr19:3830038(-) A-I      intronic chr19:3846193(-) A-I      intronic chr19:3855030(-) A-I      intronic chr19:3822651(-) A-I      intronic chr19:3866033(-) A-I      intronic chr19:3830275(-) A-I      intronic chr19:3829603(-) A-I      intronic chr19:3866016(-) A-I      intronic chr19:3826708(-) A-I      intronic chr19:3813070(-) A-I      intronic chr19:3829246(-) A-I      intronic chr19:3805016(-) A-I      3'UTR chr19:3843347(-) A-I      intronic chr19:3812814(-) A-I      intronic chr19:3809779(-) A-I      intronic chr19:3812106(-) A-I      intronic chr19:3829692(-) A-I      intronic chr19:3861812(-) A-I      intronic chr19:3857115(-) A-I      intronic chr19:3822628(-) A-I      intronic chr19:3854031(-) A-I      intronic chr19:3830427(-) A-I      intronic chr19:3822378(-) A-I      intronic chr19:3854976(-) A-I      intronic chr19:3861538(-) A-I      intronic chr19:3812944(-) A-I      intronic chr19:3864370(-) A-I      intronic chr19:3804930(-) A-I      3'UTR chr19:3822708(-) A-I      intronic chr19:3805542(-) A-I      3'UTR chr19:3857688(-) A-I      intronic chr19:3826602(-) A-I      intronic chr19:3829608(-) A-I      intronic chr19:3845760(-) A-I      intronic chr19:3827957(-) A-I      intronic chr19:3864196(-) A-I      intronic chr19:3805023(-) A-I      3'UTR chr19:3832493(-) A-I      intronic chr19:3866085(-) A-I      intronic chr19:3862424(-) A-I      intronic chr19:3811725(-) A-I      intronic chr19:3805145(-) A-I      3'UTR chr19:3855175(-) A-I      intronic chr19:3812146(-) A-I      intronic chr19:3854859(-) A-I      intronic chr19:3846178(-) A-I      intronic chr19:3822627(-) A-I      intronic chr19:3804935(-) A-I      3'UTR chr19:3853845(-) A-I      intronic chr19:3855000(-) A-I      intronic chr19:3824284(-) A-I      intronic chr19:3864276(-) A-I      intronic chr19:3853960(-) A-I      intronic chr19:3811861(-) A-I      intronic chr19:3812820(-) A-I      intronic chr19:3812367(-) A-I      intronic chr19:3805089(-) A-I      3'UTR chr19:3805486(-) A-I      3'UTR chr19:3830426(-) A-I      intronic chr19:3829124(-) A-I      intronic chr19:3854172(-) A-I      intronic chr19:3862575(-) A-I      intronic chr19:3829057(-) A-I      intronic chr19:3805552(-) A-I      3'UTR chr19:3856758(-) A-I      intronic chr19:3842135(-) A-I      intronic chr19:3854854(-) A-I      intronic chr19:3830080(-) A-I      intronic chr19:3805149(-) A-I      3'UTR chr19:3861407(-) A-I      intronic chr19:3816408(-) A-I      intronic chr19:3855031(-) A-I      intronic chr19:3864365(-) A-I      intronic chr19:3824185(-) A-I      intronic chr19:3812872(-) A-I      intronic chr19:3829675(-) A-I      intronic chr19:3812931(-) A-I      intronic chr19:3833079(-) A-I      intronic chr19:3805621(-) A-I      3'UTR chr19:3812996(-) A-I      intronic chr19:3830272(-) A-I      intronic chr19:3830240(-) A-I      intronic chr19:3813031(-) A-I      intronic chr19:3830291(-) A-I      intronic chr19:3857224(-) A-I      intronic chr19:3812957(-) A-I      intronic chr19:3826717(-) A-I      intronic chr19:3865489(-) A-I      intronic chr19:3822408(-) A-I      intronic chr19:3818353(-) A-I      intronic chr19:3854954(-) A-I      intronic chr19:3830087(-) A-I      intronic chr19:3861408(-) A-I      intronic chr19:3809267(-) A-I      intronic chr19:3827140(-) A-I      intronic chr19:3864164(-) A-I      intronic chr19:3865968(-) A-I      intronic chr19:3842119(-) A-I      intronic chr19:3819608(-) A-I      intronic chr19:3832409(-) A-I      intronic chr19:3812169(-) A-I      intronic chr19:3863570(-) A-I      intronic chr19:3864138(-) A-I      intronic chr19:3830063(-) A-I      intronic chr19:3809859(-) A-I      intronic chr19:3861618(-) A-I      intronic chr19:3827943(-) A-I      intronic chr19:3812967(-) A-I      intronic chr19:3829639(-) A-I      intronic chr19:3816342(-) A-I      intronic chr19:3832392(-) A-I      intronic chr19:3809268(-) A-I      intronic chr19:3829739(-) A-I      intronic chr19:3830219(-) A-I      intronic chr19:3854296(-) A-I      intronic chr19:3829626(-) A-I      intronic chr19:3812192(-) A-I      intronic chr19:3812254(-) A-I      intronic chr19:3826463(-) A-I      intronic chr19:3830118(-) A-I      intronic chr19:3861475(-) A-I      intronic chr19:3829651(-) A-I      intronic chr19:3846153(-) A-I      intronic chr19:3855166(-) A-I      intronic chr19:3858707(-) A-I      intronic chr19:3863504(-) A-I      intronic chr19:3861841(-) A-I      intronic chr19:3853907(-) A-I      intronic chr19:3822443(-) A-I      intronic chr19:3830308(-) A-I      intronic chr19:3833062(-) A-I      intronic chr19:3822486(-) A-I      intronic chr19:3828068(-) A-I      intronic chr19:3862393(-) A-I      intronic chr19:3865516(-) A-I      intronic chr19:3830403(-) A-I      intronic chr19:3832833(-) A-I      intronic chr19:3854144(-) A-I      intronic chr19:3840802(-) A-I      intronic chr19:3854922(-) A-I      intronic chr19:3857647(-) A-I      intronic chr19:3854145(-) A-I      intronic chr19:3829632(-) A-I      intronic chr19:3861630(-) A-I      intronic chr19:3811964(-) A-I      intronic chr19:3830180(-) A-I      intronic chr19:3865612(-) A-I      intronic chr19:3856906(-) A-I      intronic chr19:3832805(-) A-I      intronic chr19:3857580(-) A-I      intronic chr19:3857612(-) A-I      intronic chr19:3855004(-) A-I      intronic chr19:3865377(-) A-I      intronic

Resource	Symbol	Editing Position	Change	SeqReg	exReg	PMID
DARNED	ZFR2	chr19:3835757(-) T-C intron -    22484847 chr19:3835762(-) T-C intron -    22484847 chr19:3842683(-) T-C intron -    22484847 chr19:3862383(-) G-C intron -    22484847 chr19:3862393(-) A-G intron -    22484847 chr19:3862442(-) G-A intron -    22484847

RNA Modification:

Resource	Symbol	ModificationPosition	Type	Genomic Context	PMID
RMBase	ZFR2	chr19:3804566-3804567(-) m6A 3'UTR       25456834 chr19:3804574-3804575(-) m6A 3'UTR       25456834 chr19:3804587-3804588(-) m6A 3'UTR       25456834 chr19:3804632-3804633(-) m6A 3'UTR       25456834 chr19:3804721-3804722(-) m6A 3'UTR       25456834 chr19:3804779-3804780(-) m6A 3'UTR       25456834 chr19:3804859-3804860(-) m6A 3'UTR       25456834 chr19:3804864-3804865(-) m6A 3'UTR       25456834 chr19:3804872-3804873(-) m6A 3'UTR       25456834 chr19:3804880-3804881(-) m6A 3'UTR       25456834 chr19:3804888-3804889(-) m6A 3'UTR       25456834 chr19:3804904-3804905(-) m6A 3'UTR       25456834 chr19:3804929-3804930(-) m6A 3'UTR       25456834 chr19:3852293-3852294(-) m6A 3'UTR//intron       25456834 chr19:3852448-3852449(-) m6A 3'UTR//intron       25456834//24981863 chr19:3852465-3852466(-) m6A 3'UTR//CDS//intron       25456834//24981863 chr19:3852550-3852551(-) m6A 3'UTR//CDS//intron       25456834//24981863 chr19:3852598-3852599(-) m6A 3'UTR//CDS//intron       25456834//24981863 chr19:3855419-3855420(-) m6A 3'UTR//CDS//intron       25456834

RNA Localization:

Resource	Symbol	Subcellular Localization	Tissue or Cell Line	PMID
RNALocate	hsa-miR-365a-5p	Exosome Plasma     23663360 Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     - Microvesicle Seminal plasma     23539611 Microvesicle Fibroblasts|Mesenchymal stem cells     - Mitochondrion Skeletal muscle myoblasts     21637849 Mitochondrion Cell line (HEK-293|HeLa)     22984580
	ZFR2	Exosome Blood     -

Interaction Network (The top 100 interactions):

Interactor1: hsa-miR-365a-5p
Interactor2: ZFR2

Evidence Support:

Weak-Evidence	RNA-Seq
Prediction-Evidence	Targetscan
Support Database	ViRBase

References:

PMID	31570108	Target region	None
Source	ViRBase	Interactor1 expression	None
Tissue or cell line	ARPE-19 human RPE cells	Interactor2 expression	None
Description	Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).