Detail Information

Basic Information:


  VIRBase ID:  

HHID00014494

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5908

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           UBAC1:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p UBAC1
miRBase
Accession/Entrez ID		 MIMAT0009199 10422
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - GBDR1//KPC2//UBADC1

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR UBAC1
chr9:138845360(-) A-I      intronic
chr9:138842985(-) A-I      intronic
chr9:138845345(-) A-I      intronic
chr9:138845301(-) A-I      intronic
chr9:138845287(-) A-I      intronic
chr9:138828438(-) A-I      intronic
chr9:138828468(-) A-I      intronic
chr9:138828472(-) A-I      intronic
chr9:138826824(-) A-I      intronic
chr9:138826757(-) A-I      intronic
chr9:138840736(-) A-I      intronic
chr9:138840833(-) A-I      intronic
chr9:138845339(-) A-I      intronic
chr9:138845436(-) A-I      intronic
chr9:138827295(-) A-I      intronic
chr9:138828496(-) A-I      intronic
chr9:138828523(-) A-I      intronic
chr9:138829205(-) A-I      intronic
chr9:138840733(-) A-I      intronic
chr9:138842799(-) A-I      intronic
chr9:138845437(-) A-I      intronic
chr9:138828372(-) A-I      intronic
chr9:138842801(-) A-I      intronic
chr9:138828612(-) A-I      intronic
chr9:138828478(-) A-I      intronic
chr9:138826970(-) A-I      intronic
chr9:138826942(-) A-I      intronic
chr9:138826473(-) A-I      intronic
chr9:138826988(-) A-I      intronic
chr9:138842844(-) A-I      intronic
chr9:138826492(-) A-I      intronic
chr9:138826317(-) A-I      intronic
chr9:138826799(-) A-I      intronic
chr9:138849954(-) A-I      intronic
chr9:138842954(-) A-I      intronic
chr9:138842968(-) A-I      intronic
chr9:138829108(-) A-I      intronic
chr9:138826262(-) A-I      intronic
chr9:138839252(-) A-I      intronic
chr9:138829129(-) A-I      intronic
chr9:138826406(-) A-I      intronic
chr9:138843336(-) A-I      intronic
chr9:138828439(-) A-I      intronic
chr9:138826939(-) A-I      intronic
chr9:138826394(-) A-I      intronic
chr9:138826947(-) A-I      intronic
chr9:138826854(-) A-I      intronic
chr9:138828477(-) A-I      intronic
chr9:138842959(-) A-I      intronic
chr9:138826864(-) A-I      intronic
chr9:138839275(-) A-I      intronic
chr9:138842747(-) A-I      intronic
chr9:138826419(-) A-I      intronic
chr9:138828512(-) A-I      intronic
chr9:138826339(-) A-I      intronic
chr9:138840852(-) A-I      intronic
chr9:138840750(-) A-I      intronic
chr9:138843404(-) A-I      intronic
chr9:138827015(-) A-I      intronic
chr9:138835155(-) A-I      intronic
chr9:138826761(-) A-I      intronic
chr9:138827016(-) A-I      intronic
chr9:138829138(-) A-I      intronic
chr9:138829204(-) A-I      intronic
chr9:138829124(-) A-I      intronic
chr9:138826895(-) A-I      intronic
chr9:138826263(-) A-I      intronic
chr9:138829121(-) A-I      intronic
chr9:138827395(-) A-I      intronic
chr9:138828440(-) A-I      intronic
chr9:138829139(-) A-I      intronic
chr9:138845359(-) A-I      intronic
chr9:138826358(-) A-I      intronic
chr9:138840840(-) A-I      intronic
chr9:138827480(-) A-I      intronic
chr9:138826250(-) A-I      intronic

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase UBAC1
chr9:138824938-138824939(-) m6A 3'UTR//exon       24284625//24209618//27773535//22608085
chr9:138825085-138825086(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr9:138825136-138825137(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr9:138825162-138825163(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//28052920//27773535//27371828//27773536//22575960//22608085
chr9:138825175-138825176(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr9:138825189-138825190(-) m6A 3'UTR//exon       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22575960//22608085
chr9:138825262-138825263(-) m6A CDS//exon       24284625//24209618//24981863//27773536//22608085
chr9:138825330-138825331(-) m6A CDS//exon       24284625//24209618//27773536
chr9:138825339-138825340(-) m6A CDS//exon       24284625//24209618//27773536
chr9:138825351-138825352(-) m6A CDS//exon       24284625//27773536
chr9:138830076-138830077(-) m6A CDS//exon       24284625//27773536
chr9:138830159-138830160(-) m6A CDS//exon       24284625//27773536
chr9:138830186-138830187(-) m6A CDS//exon       27773536
chr9:138831540-138831541(-) m6A CDS//exon       27773536
chr9:138834050-138834051(-) m6A exon//intron       27773536
chr9:138837036-138837037(-) m6A CDS//exon       27773536
chr9:138837048-138837049(-) m6A CDS//exon       27773536
chr9:138837059-138837060(-) m6A CDS//exon       27773536
chr9:138837158-138837159(-) m6A exon//intron       -
chr9:138837764-138837765(-) m6A CDS//exon       -
chr9:138838149-138838150(-) m6A CDS//exon       27773535
chr9:138838205-138838206(-) m6A CDS//exon       27773535
chr9:138838210-138838211(-) m6A CDS//exon       27773535
chr9:138839657-138839658(-) m6A CDS//exon       24981863
chr9:138839674-138839675(-) m6A CDS//exon       24981863//27773535
chr9:138839740-138839741(-) m6A CDS//exon       24981863//27773535
chr9:138839745-138839746(-) m6A CDS//exon       24981863//27773535
chr9:138839775-138839776(-) m6A exon//intron       24981863//27773535
chr9:138847016-138847017(-) Gm intron       -
chr9:138847145-138847146(-) m6A CDS//exon       24981863//26404942
chr9:138847154-138847155(-) m6A CDS//exon       24981863//26404942
chr9:138847170-138847171(-) m6A CDS//exon       24981863//26404942
chr9:138852910-138852911(-) m6A CDS//exon       27773536

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
UBAC1
Chromatin K562 cells     -
Cytosol K562 cells     -
Exosome Blood     -
Nucleolus K562 cells     -
Nucleoplasm K562 cells     -
Nucleus HeLa-S3 cells|K562 cells     -

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: UBAC1

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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