Detail Information

Basic Information:


  VIRBase ID:  

HHID00014364

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5908

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-365a-5p:           ZNF24:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-365a-5p ZNF24
miRBase
Accession/Entrez ID		 MIMAT0009199 7572
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - KOX17//RSG-A//Zfp191//ZNF191//ZSCAN3

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-365a-5p
rs1166908611 chr16:14309308    T/C
rs1368596991 chr16:14309314    G/A
rs1380926089 chr16:14309318    A/G
rs1396179427 chr16:14309310    G/C
rs1428928383 chr16:14309320    G/A
rs773834113 chr16:14309301    G/C

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase ZNF24
chr18:32912236-32912237(-) m6A 3'UTR       27773535
chr18:32912259-32912260(-) m6A 3'UTR       27773535
chr18:32912370-32912371(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22608085
chr18:32912439-32912440(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:32912468-32912469(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//27773535//27371828//22575960//22608085
chr18:32912519-32912520(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:32912526-32912527(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:32912561-32912562(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22575960//22608085
chr18:32912573-32912574(-) m6A 3'UTR       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//22608085
chr18:32912700-32912701(-) m6A 3'UTR       24284625//22608085
chr18:32913298-32913299(-) m6A 3'UTR       24981863//27773535
chr18:32913394-32913395(-) m6A 3'UTR       24981863//27773535
chr18:32913416-32913417(-) m6A 3'UTR       27773535
chr18:32914823-32914824(-) m6A 3'UTR       25456834//24981863
chr18:32914833-32914834(-) m6A 3'UTR       25456834//24981863
chr18:32914838-32914839(-) m6A 3'UTR       25456834//24981863
chr18:32915775-32915776(-) m6A 3'UTR       26404942
chr18:32915783-32915784(-) m6A 3'UTR       26404942
chr18:32915804-32915805(-) m6A 3'UTR       26404942
chr18:32916432-32916433(-) m6A 3'UTR       27773535
chr18:32916548-32916549(-) Y 3'UTR       25219674
chr18:32916614-32916615(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr18:32916633-32916634(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr18:32916669-32916670(-) m6A 3'UTR       24284625//24981863//26404942//27773535//22608085
chr18:32916767-32916768(-) m6A 3'UTR       24981863//27773535//22608085
chr18:32916777-32916778(-) m6A 3'UTR       24981863//27773535//22608085
chr18:32916873-32916874(-) m6A 3'UTR       24981863//27773535//22608085
chr18:32916917-32916918(-) m6A 3'UTR       24981863//27773535//22608085
chr18:32916989-32916990(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr18:32917002-32917003(-) m6A 3'UTR       24981863//26404942//27773535//22608085
chr18:32917139-32917140(-) m6A 3'UTR       24209618//24981863//26404942//27773535//22608085
chr18:32917219-32917220(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917234-32917235(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917246-32917247(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917303-32917304(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr18:32917387-32917388(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22575960//22608085
chr18:32917433-32917434(-) Y 3'UTR//CDS       26075521
chr18:32917471-32917472(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917528-32917529(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917555-32917556(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917608-32917609(-) m6A 3'UTR//CDS       24284625//24209618//24981863//26404942//27773535//22608085
chr18:32917719-32917720(-) m6A 3'UTR//CDS       24284625//24981863//27773535//27371828//22608085
chr18:32918106-32918107(-) m6A 3'UTR//intron       27773535
chr18:32919839-32919840(-) m6A CDS       24284625//24981863//27371828//27773536
chr18:32919899-32919900(-) m6A CDS       24284625//24981863//27371828//27773536//22608085
chr18:32920200-32920201(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32920215-32920216(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//27773536//22608085
chr18:32920286-32920287(-) m6A CDS       24284625//24209618//25456834//24981863//28052920//26404942//27773535//27371828//27773536//22575960//22608085
chr18:32920347-32920348(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27773535//27371828//22575960//22608085
chr18:32920389-32920390(-) m6A CDS       24284625//24209618//25456834//24981863//27773535//27371828//22608085
chr18:32920474-32920475(-) m6A CDS       24284625//24209618//25456834//24981863//26404942//27371828//22608085
chr18:32920486-32920487(-) m6A CDS       24284625//24209618//24981863//27371828//22608085

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-365a-5p
Exosome Plasma     23663360
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Seminal plasma     23539611
Microvesicle Fibroblasts|Mesenchymal stem cells     -
Mitochondrion Skeletal muscle myoblasts     21637849
Mitochondrion Cell line (HEK-293|HeLa)     22984580
ZNF24
Cytosol Human myelogenous leukemia cell line (K-562)     21613539
Cytosol K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus Colon cancer cells     24393600

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-365a-5p
Interactor2: ZNF24

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence DIANA-microT//Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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