Detail Information

Basic Information:


  VIRBase ID:  

HHID00013830

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

  Predicted Binding:

 

      hsa-miR-1305:           IMMP1L:      

      *It may take a few minutes to display results.

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-1305 IMMP1L
miRBase
Accession/Entrez ID		 MIMAT0005893 196294
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - IMMP1//IMP1//IMP1-LIKE

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-1305
rs1391055872 chr4:182169359    G/A
rs1460502740 chr4:182169360    A/G
rs190183451 chr4:182169358    G/A
rs760149578 chr4:182169357    G/T
rs774577022 chr4:182169356    T/C
rs911409575 chr4:182169355    A/C
rs911409575 chr4:182169355    A/G
rs931724077 chr4:182169352    C/G
rs971149992 chr4:182169361    G/A
rs985999312 chr4:182169354    A/G
rs1192955520 chr4:182169349    A/G
rs1240810346 chr4:182169350    C/A
rs1240810346 chr4:182169350    C/T

RNA Editing:


Resource Symbol Editing Position Change Genetic Region
RADAR IMMP1L
chr11:31466319(-) A-I      intronic
chr11:31511836(-) A-I      intronic
chr11:31469810(-) A-I      intronic
chr11:31469817(-) A-I      intronic
chr11:31510269(-) A-I      intronic
chr11:31469756(-) A-I      intronic
chr11:31469769(-) A-I      intronic
chr11:31491921(-) A-I      intronic
chr11:31494825(-) A-I      intronic
chr11:31494702(-) A-I      intronic
chr11:31527957(-) A-I      intronic
chr11:31520898(-) A-I      intronic
chr11:31528038(-) A-I      intronic
chr11:31520722(-) A-I      intronic
chr11:31511795(-) A-I      intronic
chr11:31520849(-) A-I      intronic
chr11:31511791(-) A-I      intronic
chr11:31527943(-) A-I      intronic
chr11:31527961(-) A-I      intronic
chr11:31491913(-) A-I      intronic
chr11:31527980(-) A-I      intronic
chr11:31528012(-) A-I      intronic
chr11:31528068(-) A-I      intronic
chr11:31528312(-) A-I      intronic
chr11:31528341(-) A-I      intronic
chr11:31528383(-) A-I      intronic
chr11:31528714(-) A-I      intronic
chr11:31491798(-) A-I      intronic
chr11:31491795(-) A-I      intronic
chr11:31491716(-) A-I      intronic
chr11:31469744(-) A-I      intronic
chr11:31494735(-) A-I      intronic
chr11:31466313(-) A-I      intronic
chr11:31528662(-) A-I      intronic
chr11:31528707(-) A-I      intronic
chr11:31528350(-) A-I      intronic
chr11:31494801(-) A-I      intronic
chr11:31466274(-) A-I      intronic
chr11:31527982(-) A-I      intronic
chr11:31510673(-) A-I      intronic
chr11:31494725(-) A-I      intronic
chr11:31469770(-) A-I      intronic
chr11:31528049(-) A-I      intronic
chr11:31510665(-) A-I      intronic
chr11:31496188(-) A-I      intronic
chr11:31469812(-) A-I      intronic
chr11:31469850(-) A-I      intronic
chr11:31527983(-) A-I      intronic
chr11:31510664(-) A-I      intronic
chr11:31510649(-) A-I      intronic
chr11:31466252(-) A-I      intronic
chr11:31527995(-) A-I      intronic
chr11:31491705(-) A-I      intronic
chr11:31511980(-) A-I      intronic
chr11:31528645(-) A-I      intronic
chr11:31528003(-) A-I      intronic
chr11:31528252(-) A-I      intronic
chr11:31528668(-) A-I      intronic
chr11:31466316(-) A-I      intronic
chr11:31491804(-) A-I      intronic
chr11:31528814(-) A-I      intronic
chr11:31520648(-) A-I      intronic
chr11:31481652(-) A-I      intronic
chr11:31466310(-) A-I      intronic
chr11:31528066(-) A-I      intronic
chr11:31528335(-) A-I      intronic
chr11:31469773(-) A-I      intronic
chr11:31491838(-) A-I      intronic
chr11:31491919(-) A-I      intronic
chr11:31469699(-) A-I      intronic
chr11:31528304(-) A-I      intronic
chr11:31466314(-) A-I      intronic
chr11:31527908(-) A-I      intronic
chr11:31511907(-) A-I      intronic
chr11:31528019(-) A-I      intronic
chr11:31527881(-) A-I      intronic
chr11:31527955(-) A-I      intronic
chr11:31528050(-) A-I      intronic
chr11:31527951(-) A-I      intronic
chr11:31469707(-) A-I      intronic
chr11:31469774(-) A-I      intronic
chr11:31481657(-) A-I      intronic
chr11:31528622(-) A-I      intronic
chr11:31528011(-) A-I      intronic
chr11:31491812(-) A-I      intronic
chr11:31496213(-) A-I      intronic
chr11:31462211(-) A-I      intronic
chr11:31466305(-) A-I      intronic
chr11:31528702(-) A-I      intronic
chr11:31527900(-) A-I      intronic
chr11:31466315(-) A-I      intronic
chr11:31519101(-) A-I      intronic
Resource Symbol Editing Position Change SeqReg exReg PMID
DARNED IMMP1L
chr11:31462211(-) A-G intron -    22484847
chr11:31466310(-) A-G intron -    22484847
chr11:31466315(-) A-G intron -    22484847
chr11:31466316(-) A-G intron -    22484847

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase IMMP1L
chr11:31474150-31474151(-) m6A exon//intron       22608085
chr11:31474170-31474171(-) m6A exon//intron       27773535//22608085
chr11:31474224-31474225(-) m6A exon//intron       24209618//27773535//22608085
chr11:31474323-31474324(-) m6A exon//intron       25456834//27773535//27371828//22608085
chr11:31499067-31499068(-) m6A 5'UTR//exon//intron       27773535//22608085
chr11:31499148-31499149(-) m6A 5'UTR//exon//intron       27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-1305
Exosome Breast cancer cell line (MCF-7)     20976003
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Cell lines(GBM46|GBM8|HaCaT|K562|MCF-10A|MCF-7|MGG75)|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocytes     -
IMMP1L
Chromatin K562 cells     -
Exosome Blood     -
Nucleoplasm K562 cells     -
Nucleus HCC cell line (HepG2)|K562 cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID
RNAactDrug hsa-miR-1305
Panobinostat       6918837
Irinotecan       60838
Topotecan       60700
l-685,458       5479543
Palbociclib       5330286
Paclitaxel       36314
Sorafenib       216239
5-Chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine       16038120
Dovitinib       135398510
Crizotinib       11626560

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-1305
Interactor2: IMMP1L

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...