Detail Information

Basic Information:


  VIRBase ID:  

HHID00012841

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p XXcos-LUCA11.5
miRBase
Accession/Entrez ID		 MIMAT0004811 XXcos-LUCA11.5
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase XXcos-LUCA11.5
chr3:50388380-50388381(+) m6A 5'UTR       24284625//24981863
chr3:50388882-50388883(+) m6A CDS       24284625
chr3:50391128-50391129(+) m6A intron       24284625//24981863//22608085
chr3:50391235-50391236(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr3:50391244-50391245(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr3:50391266-50391267(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr3:50391283-50391284(+) m6A intron       24284625//24209618//25456834//24981863//22575960//22608085
chr3:50391376-50391377(+) m6A intron       24284625//24209618//25456834//24981863//22608085
chr3:50391416-50391417(+) m6A intron       24284625//24209618//25456834//22608085
chr3:50395569-50395570(+) m6A intron       -
chr3:50395783-50395784(+) m6A intron       24284625//27773535
chr3:50403234-50403235(+) m6A intron       25456834
chr3:50403316-50403317(+) m6A intron       25456834

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: XXcos-LUCA11.5

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

Starting a new search, please wait ...