Detail Information

Basic Information:


  VIRBase ID:  

HHID00012827

  Virus:  

Zaire ebolavirus (ZEBOV)

  Host:  

Homo sapiens

  Confidence Score:  

0.5711

  Interaction Type:  

Host-Host interaction

Interactor Information:


Interactor1 Interactor2
Symbol hsa-miR-33b-3p AC010327.2
miRBase
Accession/Entrez ID		 MIMAT0004811 AC010327.2
Organism Homo sapiens Homo sapiens
Category miRNA mRNA
Alias - -

ncRNA SNP information:


Resource Symbol SNP ID SNP Position Ref/Alt
miRNASNP-v3 hsa-miR-33b-3p
rs1014636340 chr17:17813869    C/T
rs1175344913 chr17:17813860    C/T
rs1212055173 chr17:17813859    G/C
rs1333766161 chr17:17813870    G/A
rs1359466877 chr17:17813864    A/G
rs751021350 chr17:17813857    G/A
rs1272832890 chr17:17813873    G/A
rs1296048342 chr17:17813872    G/A
rs1399118390 chr17:17813874    C/T

RNA Modification:


Resource Symbol ModificationPosition Type Genomic Context PMID
RMBase AC010327.2
chr19:55738786-55738787(+) m6A CDS       -
chr19:55740556-55740557(+) m6A 3'UTR       -
chr19:55740608-55740609(+) m6A 3'UTR       -
chr19:55741271-55741272(+) m6A 3'UTR       24284625
chr19:55741278-55741279(+) m6A 3'UTR       24284625
chr19:55741332-55741333(+) m6A 3'UTR       24284625
chr19:55741385-55741386(+) m6A 3'UTR       24284625
chr19:55741429-55741430(+) m6A 3'UTR       -
chr19:55741481-55741482(+) m6A 3'UTR       27773535
chr19:55741511-55741512(+) m6A 3'UTR       26404942//27773535
chr19:55741541-55741542(+) m6A 3'UTR       24981863//26404942//27773535

RNA Localization:


Resource Symbol Subcellular Localization Tissue or Cell Line PMID
RNALocate hsa-miR-33b-3p
Exosome Breast milk|Cell lines|Epididymal epithelial cells|Osteoblast|Plasma|Primary glioblastoma neurosphere cells|Primary keratinocyte|Saliva|Serum|Urine     -
Microvesicle Fibroblasts|Mesenchymal stem cells     -

Related Drug Information:


Resource Symbol Drug Name PubChem ID PMID
NoncoRNA hsa-miR-33b-3p
Cisplatin 5702198       27559850

Interaction Network (The top 100 interactions):


Interactor1: hsa-miR-33b-3p
Interactor2: AC010327.2

Evidence Support:


Weak-Evidence RNA-Seq
Prediction-Evidence Targetscan
Support Database ViRBase

References:


PMID 31570108 Target region None
Source ViRBase Interactor1 expression None
Tissue or cell line ARPE-19 human RPE cells Interactor2 expression None
Description Table 1 List of miRNAs that were differentially expressed between EBOV- and mock-infected human RPE cells at 24 h post-infection.Putative target genes in EBOV-infected human RPE cells were predicted from the 15 highly differentially expressed miRNAs using algorithms: 2629 targets by Diana microT; 1799 targets by miRDB; and 14315 targets by TargetScan (Additional file 5).

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